-
1
-
-
4644325609
-
Polyethylene glycol) prodrugs of the CDK inhibitor, alsterpaullone (NSC 705707): Synthesis and pharmacokinetic studies
-
Greenwald, R.B.; Zhao, H.; Xia, J.; Wu, D.; Nervi, S.; Stinson, S.F.; Majerova, E.; Bramhall, C.; Zaharevitz, D.W. Polyethylene glycol) prodrugs of the CDK inhibitor, alsterpaullone (NSC 705707): synthesis and pharmacokinetic studies. Bioconjugate Chem. 2004, 15, 1076-1083.
-
(2004)
Bioconjugate Chem
, vol.15
, pp. 1076-1083
-
-
Greenwald, R.B.1
Zhao, H.2
Xia, J.3
Wu, D.4
Nervi, S.5
Stinson, S.F.6
Majerova, E.7
Bramhall, C.8
Zaharevitz, D.W.9
-
2
-
-
0035816143
-
Polymer-drug conjugates, PDEPT and PELT: Basic principles for design and transfer from the lab to the clinic
-
Duncan, R.; Gac-Breton, S.; Keane, R.; Musila, R.; Sat, Y.N.; Satchi, R.; Searle, F. Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the lab to the clinic. J. Control. Rel. 2001, 74, 135-146.
-
(2001)
J. Control. Rel
, vol.74
, pp. 135-146
-
-
Duncan, R.1
Gac-Breton, S.2
Keane, R.3
Musila, R.4
Sat, Y.N.5
Satchi, R.6
Searle, F.7
-
3
-
-
0035816165
-
Water soluble polymers in tumor targeted delivery
-
Kopecek, J.; Kopeckova, P.; Minko, T.; Lu, Z.R.; Peterson, C.M. Water soluble polymers in tumor targeted delivery. J. Control. Rel. 2001, 74, 147-158.
-
(2001)
J. Control. Rel
, vol.74
, pp. 147-158
-
-
Kopecek, J.1
Kopeckova, P.2
Minko, T.3
Lu, Z.R.4
Peterson, C.M.5
-
4
-
-
8844259685
-
CT-2103: Emerging utility and therapy for solid tumors
-
Langer, C.J. CT-2103: emerging utility and therapy for solid tumors. Expert Opin. Investig. Drugs 2004, 13, 1501-1508.
-
(2004)
Expert Opin. Investig. Drugs
, vol.13
, pp. 1501-1508
-
-
Langer, C.J.1
-
5
-
-
2442690116
-
Cathepsin K inhibitor-polymer conjugates: Potential drugs for the treatment of osteoporosis and rheumatoid arthritis
-
Wang, D.; Li, W.; Pechar, M.; Kopeckova, P.; Bromine, D.; Kopecek, J. Cathepsin K inhibitor-polymer conjugates: potential drugs for the treatment of osteoporosis and rheumatoid arthritis. Int. J. of Pharma. 2004, 277, 73-79.
-
(2004)
Int. J. of Pharma
, vol.277
, pp. 73-79
-
-
Wang, D.1
Li, W.2
Pechar, M.3
Kopeckova, P.4
Bromine, D.5
Kopecek, J.6
-
6
-
-
4544335351
-
Hydrophilic polymer drug from a derivative of salicylic acid: Synthesis, controlled release studies and biological behavior
-
Rodriguez, G.; Gallardo, A.; Fernandez, M.; Rebuelta, M.; Bujan, J.; Bellon, J.M.; Honduvilla, N.G.; Escudero, C.; San Roman, J. Hydrophilic polymer drug from a derivative of salicylic acid: synthesis, controlled release studies and biological behavior. Macromol. Biosci. 2004, 4, 579-586.
-
(2004)
Macromol. Biosci
, vol.4
, pp. 579-586
-
-
Rodriguez, G.1
Gallardo, A.2
Fernandez, M.3
Rebuelta, M.4
Bujan, J.5
Bellon, J.M.6
Honduvilla, N.G.7
Escudero, C.8
San Roman, J.9
-
7
-
-
0032959549
-
Phase I Clinical and Pharmacokinetic Study of PK1 [N-(2-Hydroxypropyl)methacrylamide Copolymer Doxorubicin]: First Member of a New Class of Chemotherapeutic Agents-Drug-Polymer Conjugates
-
Vasey, P.A.; Kaye, S.B.; Morrison, R.; Twelves, C.; Wilson, P.; Duncan, R.; Thomson, A.H.; Murray, L.S.; Hilditch, T.E.; Murray, T.; Burtles, S.; Fraier, D.; Frigerio, E.; Cassidy, J. Phase I Clinical and Pharmacokinetic Study of PK1 [N-(2-Hydroxypropyl)methacrylamide Copolymer Doxorubicin]: First Member of a New Class of Chemotherapeutic Agents-Drug-Polymer Conjugates. Clin. Cancer Res. 1999, 5, 83-94.
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 83-94
-
-
Vasey, P.A.1
Kaye, S.B.2
Morrison, R.3
Twelves, C.4
Wilson, P.5
Duncan, R.6
Thomson, A.H.7
Murray, L.S.8
Hilditch, T.E.9
Murray, T.10
Burtles, S.11
Fraier, D.12
Frigerio, E.13
Cassidy, J.14
-
8
-
-
0023450012
-
w) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
-
w) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. J. Biomed. Mater. Res. 1987, 21, 1341-1358.
-
(1987)
J. Biomed. Mater. Res
, vol.21
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
9
-
-
0037133087
-
PLGA-mPEG nanoparticles of cisplatin: In vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties
-
Avgoustakis, K.; Beletsi, A.; Panagi, Z.; Klepetsanis, P.; Karydas, A.G.; Ithakissios, D.S. PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties. J. Control. Rel. 2002, 79, 123-135.
-
(2002)
J. Control. Rel
, vol.79
, pp. 123-135
-
-
Avgoustakis, K.1
Beletsi, A.2
Panagi, Z.3
Klepetsanis, P.4
Karydas, A.G.5
Ithakissios, D.S.6
-
10
-
-
1642523582
-
Controlled drug release from hydrogel nanoparticle networks
-
Huang, G.; Gao, J.; Hu, Z.; St. John, J.V.; Ponder, B.C.; Moro, D. Controlled drug release from hydrogel nanoparticle networks. J. Control. Rel. 2004, 94, 303-311.
-
(2004)
J. Control. Rel
, vol.94
, pp. 303-311
-
-
Huang, G.1
Gao, J.2
Hu, Z.3
St. John, J.V.4
Ponder, B.C.5
Moro, D.6
-
11
-
-
0004226645
-
Synthetic polymeric drugs
-
U.S. Pat. 5,037,883
-
Kopecek, J.; Rejmanova, P.; Strohalm, J.; Ulbrich, K.; Rihova, B.; Chytry, V.; Lloyd, J.B.; Duncan, R. Synthetic polymeric drugs. U.S. Pat. 5,037,883, 1991.
-
(1991)
-
-
Kopecek, J.1
Rejmanova, P.2
Strohalm, J.3
Ulbrich, K.4
Rihova, B.5
Chytry, V.6
Lloyd, J.B.7
Duncan, R.8
-
12
-
-
0036875839
-
-
Gianasi, E.; Buckley, R.G.; Latigo, J.; Wasil, M.; Duncan, R. HPMA Copolymer Platinates Containing Dicarboxylato Ligands. Preparation, Characterization, and In Vitro and In Vivo Evaluation. J. Drug Targeting 2002, 10, 549-556.
-
Gianasi, E.; Buckley, R.G.; Latigo, J.; Wasil, M.; Duncan, R. HPMA Copolymer Platinates Containing Dicarboxylato Ligands. Preparation, Characterization, and In Vitro and In Vivo Evaluation. J. Drug Targeting 2002, 10, 549-556.
-
-
-
-
13
-
-
36949030565
-
O-amidomalonate platinum complexes
-
U.S. Pat. 6,692,734
-
Stewart, D.R.; Rice, J.R. St. John, J.V. N,O-amidomalonate platinum complexes. U.S. Pat. 6,692,734, 2004.
-
(2004)
-
-
Stewart, D.R.1
Rice2
St, J.R.3
John, J.V.N.4
-
15
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
-
Maeda, H.; Wu, J.; Sawa, T.; Matsumura, Y.; Hori, K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Rel. 2000, 65, 271-284.
-
(2000)
J. Control. Rel
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
16
-
-
0034989921
-
Synthetic Macromolecular Drug Carriers: Biodistribution of Poly[(N-2-hydroxypropyl)methacrylamide] Copolymers and Their Accumulation in Solid Rat Tumors
-
Kissel, M.; Peschke, P.; Subr, V.; Ulbrich, K.; Schuhmacher, J.; Debus, J.; Friedrich, E. Synthetic Macromolecular Drug Carriers: Biodistribution of Poly[(N-2-hydroxypropyl)methacrylamide] Copolymers and Their Accumulation in Solid Rat Tumors. PDA J. of Pharma. Sci. & Tech. 2001, 55, 191-201.
-
(2001)
PDA J. of Pharma. Sci. & Tech
, vol.55
, pp. 191-201
-
-
Kissel, M.1
Peschke, P.2
Subr, V.3
Ulbrich, K.4
Schuhmacher, J.5
Debus, J.6
Friedrich, E.7
-
17
-
-
0036288984
-
The cellular pharmacology of oxaliplatin resistance
-
Mishima, M.; Samimi, G.; Kondo, A.; Lin, X.; Howell, S.B. The cellular pharmacology of oxaliplatin resistance. Eur. J. Cancer 2002, 38, 1405-1412.
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 1405-1412
-
-
Mishima, M.1
Samimi, G.2
Kondo, A.3
Lin, X.4
Howell, S.B.5
-
18
-
-
0035286685
-
The potential use of receptor-mediated endocytosis for oral drug delivery
-
Russell-Jones, G.J. The potential use of receptor-mediated endocytosis for oral drug delivery. Adv. Drug Del. Rev. 2001, 47, 21-37.
-
(2001)
Adv. Drug Del. Rev
, vol.47
, pp. 21-37
-
-
Russell-Jones, G.J.1
-
19
-
-
0032580526
-
Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells
-
Wang, S.; Low, P.S. Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells. J. Control. Rel. 1998, 53, 39-48.
-
(1998)
J. Control. Rel
, vol.53
, pp. 39-48
-
-
Wang, S.1
Low, P.S.2
-
20
-
-
0032719515
-
Intestinal absorption of water soluble vitamins. Focus on molecular mechanism of the intestinal biotin transport process
-
Ramaswamy, K. Intestinal absorption of water soluble vitamins. Focus on molecular mechanism of the intestinal biotin transport process. Am. J. Physiol. 1999, 277, C603-604.
-
(1999)
Am. J. Physiol
, vol.277
-
-
Ramaswamy, K.1
-
21
-
-
0037122675
-
Hydrogels for biomedical applications
-
Hoffman, A.S. Hydrogels for biomedical applications. Adv. Drug Del. Rev. 2002, 43, 3-12.
-
(2002)
Adv. Drug Del. Rev
, vol.43
, pp. 3-12
-
-
Hoffman, A.S.1
-
22
-
-
4444229336
-
Konjac Glucomannan-graft-Acrylic Acid Hydrogels Containing Azo Crosslinker for Colon-Specific Delivery
-
Liu, Z.L.; Hu, H.; Zhuo, R.X. Konjac Glucomannan-graft-Acrylic Acid Hydrogels Containing Azo Crosslinker for Colon-Specific Delivery. J. Polym. Sci. Part A: Polym. Chem. 2004, 42, 4370-4378.
-
(2004)
J. Polym. Sci. Part A: Polym. Chem
, vol.42
, pp. 4370-4378
-
-
Liu, Z.L.1
Hu, H.2
Zhuo, R.X.3
-
23
-
-
0035988697
-
Composition Options for Tissue Engineered Bone
-
Orban, J.M.; Marra, K.G.; Hollinger, J.O. Composition Options for Tissue Engineered Bone. Tissue Eng. 2002, 8, 529-539.
-
(2002)
Tissue Eng
, vol.8
, pp. 529-539
-
-
Orban, J.M.1
Marra, K.G.2
Hollinger, J.O.3
|