Pancreatic tissue formation from murine embryonic stem cells in vitro

Differentiation

Volumn 75, Issue 1, 2007, Pages 1-11

  Nakanishi, Mio ^a   Hamazaki, Tatsuo S ^a,b   Komazaki, Shinji ^c   Okochi, Hitoshi ^b   Asashima, Makoto ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c SAITAMA MEDICAL UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Activin; Mouse embryonic stem cells; Pancreas; Pancreatic and duodenal homeobox 1 (Pdx 1); ptf1a p48; Retinoic acid; Sonic hedgehog; cells

Indexed keywords

ACTIVIN; RETINOIC ACID; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENDOCRINE CELL; EXOCRINE CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PANCREAS; PANCREAS DUCT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE INDUCTION;

ERINACEIDAE; MURINAE;

EID: 33846331593     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1111/j.1432-0436.2006.00109.x     Document Type: Article

References (37)

1. Blyszczuk, P., Czyz, J., Kania, G., Wagner, M., Roll, U., St-Onge, L. and Wobus, A.M. (2003) Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci USA 100:998-1003.
2. Blyszczuk, P. and Wobus, A.M. (2004) Stem cells and pancreatic differentiation in vitro. J Biotechnol 113:3-13.
3. Chen, Y., Pan, F.C., Brandes, N., Afelik, S., Solter, M. and Pieler, T. (2004) Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev Biol 271:144-160.
4. D'Amour, K.A., Agulnick, A.D., Eliazer, S., Kelly, O.G., Kroon, E. and Baetge, E.E. (2005) Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 23:1534-1541.
5. Delacour, A., Nepote, V., Trumpp, A. and Herrera, P.L. (2004) Nestin expression in pancreatic exocrine cell lineages. Mech Dev 121:3-14.
6. Gittes, G.K. and Rutter, W.J. (1992) Onset of cell-specific gene expression in the developing mouse pancreas. Proc Natl Acad Sci USA 89:1128-1132.
7. Hebrok, M., Kim, S.K. and Melton, D.A. (1998) Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev 12:1705-1713.
8. Hori, Y., Rulifson, I.C., Tsai, B.C., Heit, J.J., Cahoy, J.D. and Kim, S.K. (2002) Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells. Proc Natl Acad Sci USA 99:16105-16110.
9. Ishii, T., Yasuchika, K., Fujii, H., Hoppo, T., Baba, S., Naito, M., Machimoto, T., Kamo, N., Suemori, H., Nakatsuji, N. and Ikai, I. (2005) In vitro differentiation and maturation of mouse embryonic stem cells into hepatocytes. Exp Cell Res 309:68-77.
10. Kania, G., Blyszczuk, P. and Wobus, A.M. (2004) The generation of insulin-producing cells from embryonic stem cells - a discussion of controversial findings. Int J Dev Biol 48:1061-1064.
11. Kim, D., Gu, Y., Ishii, M., Fujimiya, M., Qi, M., Nakamura, N., Yoshikawa, T., Sumi, S. and Inoue, K. (2003) In vivo functioning and transplantable mature pancreatic islet-like cell clusters differentiated from embryonic stem cell. Pancreas 27:e34-e41.
12. Kim, S.K. and Hebrok, M. (2001) Intercellular signals regulating pancreas development and function. Genes Dev 15:111-127.
13. Kim, S.K., Hebrok, M., Li, E., Oh, S.P., Schrewe, H., Harmon, E.B., Lee, J.S. and Melton, D.A. (2000) Activin receptor patterning of foregut organogenesis. Genes Dev 14:1866-1871.
14. Kim, S.K., Hebrok, M. and Melton, D.A. (1997) Notochord to endoderm signaling is required for pancreas development. Development 124:4243-4252.
15. Kubo, A., Shinozaki, K., Shannon, J.M., Kouskoff, V., Kennedy, M., Woo, S., Fehling, H.J. and Keller, G. (2004) Development of definitive endoderm from embryonic stem cells in culture. Development 131:1651-1662.
16. Kumar, M. and Melton, D. (2003) Pancreas specification: a budding question. Curr Opin Genet Dev 13:401-407.
17. Le Douarin, N. (2000) Des Chimeras, des Clones et des Genes. Odile Jacob, Paris.
18. Leon-Quinto, T., Jones, J., Skoudy, A., Burcin, M. and Soria, B. (2004) In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells. Diabetologia 47:1442-1451.
19. Loebel, D.A., Watson, C.M., De Young, R.A. and Tam, P.P. (2003) Lineage choice and differentiation in mouse embryos and embryonic stem cells. Dev Biol 264:1-14.
20. Lumelsky, N., Blondel, O., Laeng, P., Velasco, I., Ravin, R. and McKay, R. (2001) Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292:1389-1394.
21. Miralles, F., Czernichow, P. and Scharfmann, R. (1998) Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development. Development 125:1017-1024.
22. Miyazaki, S., Yamato, E. and Miyazaki, J. (2004) Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells. Diabetes 53:1030-1037.
23. Moriya, N., Komazaki, S., Takahashi, S., Yokota, C. and Asashima, M. (2000) In vitro pancreas formation from Xenopus ectoderm treated with activin and retinoic acid. Dev Growth Differ 42:593-602.
24. Percival, A.C. and Slack, J.M. (1999) Analysis of pancreatic development using a cell lineage label. Exp Cell Res 247:123-132.
25. Ritvos, O., Tuuri, T., Eramaa, M., Sainio, K., Hilden, K., Saxen, L. and Gilbert, S.F. (1995) Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse. Mech Dev 50:229-245.
26. Sanvito, F., Herrera, P.L., Huarte, J., Nichols, A., Montesano, R., Orci, L. and Vassalli, J.D. (1994) TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro. Development 120:3451-3462.
27. Selander, L. and Edlund, H. (2002) Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. 113:189-192.
28. Shi, Y., Hou, L., Tang, F., Jiang, W., Wang, P., Ding, M. and Deng, H. (2005) Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 23:656-662.
29. Shiozaki, S., Tajima, T., Zhang, Y.Q., Furukawa, M., Nakazato, Y. and Kojima, I. (1999) Impaired differentiation of endocrine and exocrine cells of the pancreas in transgenic mouse expressing the truncated type II activin receptor. Biochim Biophys Acta 1450:1-11.
30. Shiroi, A., Yoshikawa, M., Yokota, H., Fukui, H., Ishizaka, S., Tatsumi, K. and Takahashi, Y. (2002) Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone. Stem Cells 20:284-292.
31. Slack, J.M. (1995) Developmental biology of the pancreas. Development 121:1569-1580.
32. Soria, B., Roche, E., Berna, G., Leon-Quinto, T., Reig, J.A. and Martin, F. (2000) Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49:157-162.
33. Stafford, D., Hornbruch, A., Mueller, P.R. and Prince, V.E. (2004) A conserved role for retinoid signaling in vertebrate pancreas development. Dev Genes Evol 214:432-441.
34. Stafford, D. and Prince, V.E. (2002) Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Curr Biol 12:1215-1220.
35. Yamada, T., Yoshikawa, M., Kanda, S., Kato, Y., Nakajima, Y., Ishizaka, S. and Tsunoda, Y. (2002) In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green. Stem Cells 20:146-154.
36. Yamaoka, T., Idehara, C., Yano, M., Matsushita, T., Yamada, T., Ii, S., Moritani, M., Hata, J., Sugino, H., Noji, S. and Itakura, M. (1998) Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants. J Clin Invest 102:294-301.
37. Yasunaga, M., Tada, S., Torikai-Nishikawa, S., Nakano, Y., Okada, M., Jakt, L.M., Nishikawa, S., Chiba, T., Era, T. and Nishikawa, S. (2005) Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol 23:1542-1550.