The Spn4 gene from Drosophila melanogaster is a multipurpose defence tool directed against proteases from three different peptidase families

Biochemical Journal

Volumn 401, Issue 1, 2007, Pages 325-331

  Brüning, Mareke ^a   Lummer, Martina ^a   Bentele, Caterina ^a   Smolenaars, Marcel M W ^b   Rodenburg, Kees W ^b   Ragg, Hermann ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cysteine protease inhibitor; Endoplasmic reticulum (ER) retention signal; Furin; Serine protease inhibitor; Serpin

Indexed keywords

INTRACELLULAR RESIDENTS; MULTIPLE ANTIPROTEOLYTIC FUNCTIONS; SINGLE SERPIN SCAFFOLD;

CATALYSIS; GENES; GENETIC ENGINEERING;

ENZYME INHIBITION;

CHYMOTRYPSIN; CYSTEINE PROTEINASE; FURIN; PEPTIDASE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSCRIPTION; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PANCREATIC ELASTASE; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SERPINS;

DROSOPHILA MELANOGASTER;

EID: 33846284555     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060648     Document Type: Article

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