Peri-implant bone formation and implant integration strength of peptide-modified p(AAm-co-EG/AAc) interpenetrating polymer network-coated titanium implants

Journal of Biomedical Materials Research - Part A

Volumn 80, Issue 2, 2007, Pages 306-320

  Barber, Thomas A ^a   Ho, James E ^a,b   De Ranieri, Aladino ^c   Virdi, Amarjit S ^c   Sumner, Dale R ^c   Healy, Kevin E ^a,b  

^a University of California at Berkeley   (United States)

^b Lawrence Berkeley National Laboratory   (United States)

^c RUSH MEDICAL COLLEGE   (United States)

Author keywords

Hydroxyapatite; Osseointegration; RGD; Titanium; Tricalcium phosphate

Indexed keywords

BONE-IMPLANT BONDING; OSSEOINTEGRATION; TRICALCIUM PHOSPHATE;

AMINO ACIDS; COMPUTERIZED TOMOGRAPHY; CORRELATION METHODS; IMPLANTS (SURGICAL); INTERPENETRATING POLYMER NETWORKS; TITANIUM ALLOYS;

BONE;

ARGINYLGLYCYLASPARTIC ACID; BONE SIALOPROTEIN; CALCIUM PHOSPHATE; HYDROXYAPATITE; MACROGOL; PEPTIDE DERIVATIVE; POLY(ACRYLAMIDE CO ETHYLENE GLYCOL ACRYLIC ACID); POLYACRYLAMIDE; POLYACRYLIC ACID; POLYMER; TITANIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMUR; IMPLANT; IN VITRO STUDY; IN VIVO STUDY; MALE; MATERIALS TESTING; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; OSTEOBLAST; RAT; SHEAR STRENGTH; WOUND HEALING;

ACRYLATES; ACRYLIC RESINS; ANIMALS; BIOMECHANICS; COATED MATERIALS, BIOCOMPATIBLE; ETHYLENE GLYCOL; FEMUR; IMPLANTS, EXPERIMENTAL; MALE; MODELS, ANIMAL; OLIGOPEPTIDES; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; SIALOGLYCOPROTEINS; TITANIUM;

EID: 33846267301     PISSN: 00219304     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30927     Document Type: Article

References (67)

1. Nilsson KG, Karrholm J. RSA in the assessment of aseptic loosening. J Bone Joint Surg Br 1997;78:1-3.
2. Rezania A, Thomas CH, Branger AB, Waters CM, Healy KE. The detachment strength and morphology of bone cells contacting materials modified with a peptide sequence found within bone sialoprotein. J Biomed Mater Res 1997;37:9-19.
3. Bearinger JP, Castner DG, Healy KE. Biomolecular modification of p(AAm-co-EG/AA) IPNs supports osteoblast adhesion and phenotypic expression. J Biomater Sci Polym Ed 1998;9:629-652.
4. Rezania A, Healy KE. Integrin subunits responsible for adhesion of human osteoblast-like cells to biomimetic peptide surfaces. J Orthop Res 1999;17:615-623.
5. Rezania A, Healy KE. Biomimetic peptide surfaces that regulate adhesion, spreading, cytoskeletal organization, and mineralization of the matrix deposited by osteoblast-like cells. Biotechnol Prog 1999;15:19-32.
6. Harbers GM, Healy KE. The effect of ligand type and density on osteoblast adhesion, proliferation, and matrix mineralization. J Biomed Mater Res A 2005;75:855-869.
7. Dee KC, Andersen TT, Bizios R. Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials. J Biomed Mater Res 1998;40:371-377.
8. Okamoto K, Matsuura T, Hosokawa R, Akagawa Y. RGD peptides regulate the specific adhesion scheme of osteoblasts to hydroxyapatite but not titanium. J Dent Res 1998;77:481-487.
9. Dee KC, Anderson TT, Bizios R. Osteoblast population migration characteristics on substrates modified with immobilized adhesive peptides. Biomaterials 1999;20:221-227.
10. Rezania A, Healy KE. The effect of peptide surface density on mineralization of a matrix deposited by osteogenic cells. J Biomed Mater Res 2000;52:595-600.
11. Itoh D, Yoneda S, Kuroda S, Kondo H, Umezawa A, Ohya K, Ohyama T, Kasugai S. Enhancement of osteogenesis on hydroxyapatite surface coated with synthetic peptide (EEEEEEEPRGDT) in vitro. J Biomed Mater Res 2002;62:292-298.
12. Barber TA, Golledge SL, Castner DG, Healy KE. Peptide-modified p(AAm-co-EG/AAc) IPNs grafted to bulk titanium modulate osteoblast behavior in vitro. J Biomed Mater Res 2003;64:38-47.
13. Barber TA, Gamble LJ, Castner DG, Healy KE. In vitro characterization of peptide-modified p(AAm-co-EG/AAc) IPN coated titanium implants. J Orthop Res 2006;24:1366-1376.
14. Ferris DM, Moodie GD, Dimond PM, Gioranni CW, Ehrlich MG, Valentini RF. RGD-coated titanium implants stimulate increased bone formation in vivo. Biomaterials 1999;20:2323-2331.
15. Schliephake H, Scharnweber D, Dard M, Rossler S, Sewing A, Meyer J, Hoogestraat D. Effect of RGD peptide coating of titanium implants on peri-implant bone formation in the alveolar crest. An experimental pilot study in dogs. Clin Oral Implants Res 2002;13:312-319.
16. Schliephake H, Scharnweber D, Dard M, Sewing A, Aref A, Roessler S. Functionalization of dental implant surfaces using adhesion molecules. J Biomed Mater Res B Appl Biomater 2005;73:88-96.
17. Neff JA, Caldwell KD, Tresco PA. A novel method for surface modification to promote cell attachment to hydrophobic substrates. J Biomed Mater Res 1998;40:511-519.
18. Houseman BT, Mrksich M. The microenvironment of immobilized Arg-Gly-Asp peptides is an important determinant of cell adhesion. Biomaterials 2001;22:943-955.
19. Pale-Grosdemange C, Simon ES, Prime KL, Whitesides GM. Formation of self-assembled monolayers by chemisorption of derivatives of oligo(ethylene glycol) of structure Hs(Ch2)11(Och2ch2) meta-OH on gold. J Am Chem Soc 1991;113:12-20.
20. Prime KL, Whitesides GM. Self-assembled organic monolayers: Model systems for studying adsorption of proteins at surfaces. Science 1991;252:1164-1167.
21. Holmberg K, Bergstrom K, Brink C, Osterberg E, Tiberg F, Harris JM. Effects on protein adsorption, bacterial adhesion and contact-angle of grafting PEG chains to polystyrene. J Adhes Sci Technol 1993;7:503-517.
22. Drumheller PD, Hubbell JA. Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates. Anal Biochem 1994;222:380-388.
23. Osterberg E, Bergstrom K, Holmberg K, Schuman TP, Riggs JA, Burns NL, Vanalstine JM, Harris JM. Protein-rejecting ability of surface-bound dextran in end-on and side-on configurations: Comparison to PEG. J Biomed Mater Res 1995;29:741-747.
24. Malmsten M, Emoto K, Van Alstine JM. Effect of chain density on inhibition of protein adsorption by poly(ethylene glycol)-based coatings. J Colloid Interface Sci 1998;202:507-517.
25. Sofia SJ, Premnath V, Merrill EW. Poly(ethylene oxide) grafted to silicon surfaces: Grafting density and protein adsorption. Macromolecules 1998;31:5059-5070.
26. Zhu XY, Jun Y, Staarup DR, Major RC, Danielson S, Boiadjiev V, Gladfelter WL, Bunker BC, Guo A. Grafting of high-density poly(ethylene glycol) monolayers on Si(111). Langmuir 2001;17:7798-7803.
27. Kingshott P, Thissen H, Griesser HJ. Effects of cloud-point grafting, chain length, and density of PEG layers on competitive adsorption of ocular proteins. Biomaterials 2002;23:2043-2056.
28. Xie HQ, Zhang CX, Guo JS. Castor oil polyurethane-acrylic or vinyl polymer interpenetrating polymer networks cured at room temperature. In: Klempner D, Sperling LH, Utracki LA, editors. Interpenetrating Polymer Networks. Washington, DC: American Chemical Society; 1994. pp 557-570.
29. Bearinger JP, Castner DG, Golledge SL, Rezania A, Hubchak S, Healy KE. P(AAm-co-EG) interpenetrating polymer networks grafted to oxide surfaces: Surface characterization, protein adsorption, and cell detachment studies. Langmuir 1997;13:5175-5183.
30. Suthar B, Xiao HX, Klempner D, Frisch KC. A review of kinetic studies on the formation of interpenetrating polymer networks. In: Kim SC, Sperling LH, editors. IPNs Around the World: Science and Engineering. New York: Wiley; 1997.
31. Irwin EF, Ho JE, Kane SR, Healy KE. Analysis of interpenetrating polymer networks via quartz crystal microbalance with dissipation monitoring. Langmuir 2005;21:5529-5536.
32. Harbers GM, Gamble LJ, Irwin EF, Castner DG, Healy KE. Development and characterization of a high-throughput system for assessing cell-surface receptor-ligand engagement. Langmuir 2005;21:8374-8384.
33. Amsel S, Maniatis A, Tavassoli M, Crosby W. The significance of intramedullary cancellous bone formation in the repair of bone marrow tissue. Anat Rec 1969;164:101-112.
34. Patt H, Maloney M. Bone marrow regeneration after local injury: A review. Exp Hematol 1975;3:135-148.
35. Liang C, Barnes J, Seedor J, Quartuccio H, Bolander M, Jeffrey J, Rodan G. Impaired bone activity in aged rats: Alteration at the cellular and molecular levels. Bone 1992;13:435-441.
36. Suva LJ, Seedor JG, Endo N, Quartuccio HA, Thompson DD, Bab I, Rodan GA. Pattern of gene expression following rat tibial marrow ablation. J Bone Miner Res 1993;8:379-388.
37. Bab I. Postablation bone marrow regeneration: An in vivo model to study differential regulation of bone formation and resorption. Bone 1995;17:437S-441S.
38. Tanaka H, Barnes J, Liang C. Effect of age on the expression of insulin-like growth factor-I, interleukin-6, and transforming growth factor-b mRNAs in rat femurs following marrow ablation. Bone 1996;18:473-478.
39. Tanaka H, Wakisaka A, Ogasa H, Kawai S, Liang C. Local and systemic expression of insulin-like growth factor-I (IGF-I) mRNAs in rat after bone marrow ablation. Biochem Biophys Res Commun 2001;287:1157-1162.
40. Kuroda S, Virdi A, Dai Y, Shott S, Sumner D. Patterns of gene expression during intramembranous bone regeneration in the rat femoral marrow ablation model. Calcif Tissue Int 2005;77:1-15.
41. De Ranieri A, Virdi A, Kuroda S, Shott S, Dai Y, Sumner DR. Local application of rhTGF-beta2 modulates dynamic gene expression in a rat implant model. Bone 2005;36:931-940.
42. Ishizaka M, Tanizawa T, Sofue M, Dohmae Y, Endo N, Takahashi HE. Bone particles disturb new bone formation on the interface of the titanium implant after reaming of the marrow cavity. Bone 1996;19:589-594.
43. Kuroda S, Virdi AS, Li P, Healy KE, Sumner DR. A low temperature biomimetic calcium phosphate surface enhances early implant fixation in a rat model. J Biomed Mater Res A 2004;70:66-73.
44. Hara T, Hayashi K, Nakashima Y, Kanemaru T, Iwamoto Y. The effect of hydroxyapatite coating on the bonding of bone to titanium implants in the femora of ovariectomised rats. J Bone Joint Surg Br 1999;81:705-709.
45. De Ranieri A, Virdi A, Kuroda S, Healy K, Sumner D. Saline irrigation does not affect bone formation or implant fixation strength in a rat model. J Biomed Mater Res B Appl Biomater 2005;74:712-717.
46. DHHS. Guideline on validation of the Limulus Amebocyte test as an end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices. Department of Health and Human Services; 1987.
47. Glantz SA. Primer of Biostatistics. New York, NY: McGraw-Hill; 1997. 4th ed., 473 pp.
48. Thomas KA, Cook SD. An evaluation of variables influencing implant fixation by direct bone apposition. J Biomed Mater Res 1985;19:875-901.
49. Davies JE. Mechanisms of endosseous integration. Int J Prosthodont 1998;11:391-401.
50. Ragab AA, Van De Motter R, Lavish SA, Goldberg VM, Ninomiya JT, Carlin CR, Greenfield EM. Measurement and removal of adherent endotoxin from titanium particles and implant surfaces. J Orthop Res 1999;17:803-809.
51. Cook SD, Thomas KA, Kay JF, Jarcho M. Hydroxyapatite-coated titanium for orthopedic implant applications. Clin Orthop 1988;232:225-243.
52. Ricci JL, Spivak JM, Alexander H, Blumenthal NC, Parsons JR. Hydroxyapatite ceramics and the nature of the bone-ceramic interface. Bull Hosp Jt Dis Orthop Inst 1989;49:178-191.
53. Geesink RG. Osteoconductive coatings for total joint arthroplasty. Clin Orthop 2002;395:53-65.
54. LeGeros RZ. Properties of osteoconductive biomaterials: Calcium phosphates. Clin Orthop 2002;395:81-98.
55. Veis AA, Trisi P, Papadimitriou S, Tsirlis AT, Parissis NA, Desiris AK, Lazzara RJ. Osseointegration of Osseotite (R) and machined titanium implants in autogenous bone graft. A histologic and histomorphometric study in dogs. Clin Oral Implants Res 2004;151:54-61.
56. Yamada Y, Ueda M, Naiki T, Nagasaka T. Tissue-engineered injectable bone regeneration for osseointegrated dental implants. Clin Oral Implants Res 2004;15:589-597.
57. Walenciak MT, Zimmerman MC, Harten RD, Ricci JL, Stamer DT. Biomechanical and histological analysis of an HA coated, arc deposited CPTi canine hip prosthesis. J Biomed Mater Res 1996;31:465-474.
58. Bi Y, Collier TO, Goldberg VM, Anderson JM, Greenfield EM. Adherent endotoxin mediates biological responses of titanium particles without stimulating their phagocytosis. J Orthop Res 2002;20:696-703.
59. Bi Y, Seabold JM, Kaar SG, Ragab AA, Goldberg VM, Anderson JM, Greenfield EM. Adherent endotoxin on orthopedic wear particles stimulates cytokine production and osteoclast differentiation. J Bone Miner Res 2001;16:2082-2091.
60. Cho DR, Shanbhag AS, Hong CY, Baran GR, Goldring SR. The role of adsorbed endotoxin in particle-induced stimulation of cytokine release. J Orthop Res 2002;20:704-713.
61. Lucksanasombool P, Higgs WA, Higgs RJ, Swain MV. Interfacial fracture toughness between bovine cortical bone and cements. Biomaterials 2003;24:1159-1166.
62. Herold DA, Keil K, Bruns DE. Oxidation of polyethylene glycols by alcohol dehydrogenase. Biochem Pharmacol 1989;38:73-76.
63. Talarico T, Swank A, Privalle C. Autoxidation of pyridoxalated hemoglobin polyoxyethylene conjugate. Biochem Biophys Res Commun 1998;250:354-358.
64. Collier TO, Anderson JM, Brodbeck WG, Barber T, Healy KE. Inhibition of macrophage development and foreign body giant cell formation by hydrophilic interpenetrating polymer network. J Biomed Mater Res A 2004;69:644-650.
65. Tsai WB, Grunkemeier JM, Horbett TA. Human plasma fibrinogen adsorption and platelet adhesion to polystyrene. J Biomed Mater Res 1999;44:130-139.
66. Shen M, Pan YV, Wagner MS, Hauch KD, Castner DG, Ratner BD, Horbett TA. Inhibition of monocyte adhesion and fibrinogen adsorption on glow discharge plasma deposited tetraethylene glycol dimethyl ether. J Biomater Sci Polym Ed 2001;12:961-78.
67. Collier TO, Anderson JM. Protein and surface effects on monocyte and macrophage adhesion, maturation, and survival. J Biomed Mater Res 2002;60:487-496.