Exogenous IL-10 overexpression reduces perforin production by activated allogenic CD8+ cells and prolongs cardiac allograft survival

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 1, 2007, Pages

  Oshima, Kiyohiro ^a   Cui, Guanggen ^a   Tung, Thomas ^a   Okotie, Onisuru ^a   Laks, Hillel ^a   Sen, Luyi ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCLA MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Cardiac allograft rejection; Cytokine; Gene therapy

Indexed keywords

CD8 ANTIGEN; INTERLEUKIN 10; PERFORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CYTOTOXICITY; GENE THERAPY; GRAFT REJECTION; GRAFT SURVIVAL; HEART MUSCLE; HEART MUSCLE CELL; HEART TRANSPLANTATION; HUMAN; LIPOSOMAL GENE DELIVERY SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; TRANSGENE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; GRAFT SURVIVAL; HEART TRANSPLANTATION; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MYOCARDIUM; PORE FORMING CYTOTOXIC PROTEINS; RABBITS; TRANSPLANTATION, HOMOLOGOUS; UP-REGULATION;

EID: 33846223508     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00441.2006     Document Type: Article

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