The C allele of the GNB3 C825T polymorphism of the G protein β3-subunit is associated with an increased risk for the development of oncocytic thyroid tumours

Journal of Pathology

Volumn 211, Issue 1, 2007, Pages 60-66

  Sheu, S Y ^a   Handke, S ^a   Brocker Preuss M ^a   Gorges R ^a   Frey, U H ^a   Ensinger, C ^b   Ofner D ^b   Farid, N R ^c   Siffert, W ^a   Schmid, K W ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c Osancor Biotech Inc   (United Kingdom)

Author keywords

Allele frequency; G protein; Genotyping; Oncocytic thyroid tumours; Polymorphism; Signal transduction

Indexed keywords

GENOMIC DNA; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA3 SUBUNIT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; STATISTICAL SIGNIFICANCE; THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; THYROID PAPILLARY CARCINOMA;

ADENOMA; ADENOMA, OXYPHILIC; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; CARCINOMA, PAPILLARY; CARCINOMA, PAPILLARY, FOLLICULAR; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENOTYPE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; ODDS RATIO; POLYMORPHISM, GENETIC; RISK; THYROID HORMONES; THYROID NEOPLASMS;

EID: 33846222359     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2084     Document Type: Article

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