Identification of CXCL11 as a STAT3-dependent gene induced by IFN

Journal of Immunology

Volumn 178, Issue 2, 2007, Pages 986-992

  Yang, Chuan He ^a   Wei, Lai ^a   Pfeffer, Susan R ^a   Du, Ziyun ^a   Murti, Aruna ^a   Valentine, William J ^a   Zheng, Yi ^b   Pfeffer, Lawrence M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL11 CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 2; PROTEIN P50; STAT3 PROTEIN; SYNAPTOTAGMIN I; TYROSINE;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CXCL11 GENE; DAUDI CELL; DIMERIZATION; FIBROBLAST; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; GENETIC TRANSCRIPTION; INTERFERON STIMULATED GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 33846213580     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.2.986     Document Type: Article

References (39)

1. Meraz, M. A., J. M. White, K. C. F. Sheehan, E. A. Bach, S. I. Rodig, A. S. Dighe, D. H. Kaplan, J. K. Riley, A. C. Greenlund, D. Campbell, et al. 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiological specificity in the JAK-STAT signaling pathway. Cell 84: 431-442.
2. Darnell, J. E. J., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421.
3. Pfeffer, L. M., J. E. Mullersman, S. R. Pfeffer, A. Murti, W. Shi, and C. H. Yang. 1997. STAT3 as an adapter to couple phosphatidylinositol-3 kinase to the IFNAR-1 chain of the type I IFN receptor. Science 276: 1418-1420.
4. Yang, C. H., A. Murti, and L. M. Pfeffer. 1998. STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities. Proc. Natl. Acad. Sci. USA 95: 5568-5572.
5. Yang, C. H., W. Shi, L. Basu, A. Murti, S. N. Constantinescu, L. Blatt, E. Croze, I. E. Mullersman, and L. M. Pfeffer. 1996. Direct association of STAT3 with the IFNAR1 signal transducing chain of the type I IFN receptor. J. Biol. Chem. 271: 8057-8061.
6. Kaptein, A., V. Paillard, and M. Saunders. 1996. Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J. Biol. Chem. 271: 5961-5964.
7. Constantinescu, S. N., E. Croze, C. Wang, A. Murti, L. Basu, J. E. Mullersman, and L. M. Pfeffer. 1994. The role of the interferon α/β receptor chain 1 in the structure and transmembrane signaling of the interferon α/β receptor complex. Proc. Natl. Acad. Sci. USA 91: 9602-9606.
8. Pfeffer, L. M., B. L. Eisenkraft, N. C. Reich, T. Improta, G. Baxter, S. Daniel-Issakani, and B. Strulovici. 1991. Transmembrane signaling by interferon α involves diacylglycerol production and activation of the ε isoform of protein kinase C in Daudi cells. Proc. Natl. Acad. SCi. USA 88: 7988-7992.
9. Pfeffer, L. M., N. Stebbing, and D. B. Donner. 1987. Cytoskeletal association of human α-interferon-receptor complexes in interferon-sensitive and -resistant lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 84: 3249-3253.
10. Pfeffer, L. M., and D. B. Donner. 1990. The down-regulation of α-interferon receptors in human lymphoblastoid cells: relation to cellular responsiveness to the antiproliferative action of α-interferon. Cancer Res. 50: 2654-2657.
11. Kessler, D. S., R. Pine, L. M. Pfeffer, D. E. Levy, and J. E. J. Darnell. 1988. Cells resistant to interferon are defective in activation of a promoter-binding factor. EMBO J. 7: 3779-3783.
12. Constantinescu, S. N., E. Croze, A. Murti, C. Wang, L. Basu, D. Hollander, D. Russell-Harde, V. Garcia-Martinez, J. E. Mullersman, and L. M. Pfeffer. 1995. Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex. Proc. Natl. Acad. Sci. USA 92: 10487-10491.
13. Wang, C., S. N. Constantinescu, D. J. MacEwan, B. Strulovici, L. V. Dekker, P. J. Parker, and L. M. Pfeffer. 1993. Interferonα induces protein kinase C-ε (PKC-ε) gene expression and a 4.7-kb PKC-ε-related transcript. Proc. Natl. Acad. Sci. USA 90: 6944-6948.
14. Pfeffer, L. M., D. B. Donner, and I. Tamm. 1987. Interferon-α down-regulates insulin receptors in lymphoblastoid (Daudi) cells. J. Biol. Chem. 262: 3665-3670.
15. Debidda, M., L. Wang, H. Zang, V. Poli, and Y. Zheng. 2005. A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J. Biol. Chem. 280: 17275-17285.
16. Chang, H. M., M. Paulson, M. Holko, C. M. Rice, B. R. Williams, I. Marie, and D. E. Levy. 2004. Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity. Proc. Natl. Acad. Sci. USA 101: 9578-9583.
17. Uddin, S., L. Yenush, X.-J. Sun, M. E. Sweet, M. F. White, and L. C. Platanias. 1995. Interferon-α engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3′ kinase. J. Biol. Chem. 270: 15938-15941.
18. Yang, C. H., A. Murti, S. R. Pfeffer, J. G. Kim, D. B. Donner, and L. M. Pfeffer. 2001. Interferon α/β promotes cell survival by activating NF-κB through phosphatidylinositol-3 kinase and Akt. J. Biol. Chem. 276: 13756-13761.
19. Strehlow, I., and C. Schindler. 1998. Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation. J. Biol. Chem. 273: 28049-28056.
20. Haspel, R. L., and J. E. Darnell, Jr. 1999. A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. Proc. Natl. Acad. Sci. USA 96: 10188-10193.
21. Wei, L., M. R. Sandbulte, P. G. Thomas, R. J. Webby, R. Homayouni, and L. M. Pfeffer. 2006. NFκB negatively regulates interferon-induced gene expression and anti-influenza activity. J. Biol. Chem. 281: 11678-11684.
22. Akira, S., Y. Nishio, M. Inoue, X.-J. Wang, S. Wei, T. Matsusaka, K. Yoshida, T. Sudo, M. Naruto, and T. Kishimoto. 1994. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77: 63-71.
23. Zhong, Z., Z. Wen, and J. E. J. Darnell. 1994. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264: 95-98.
24. Takeda, K., K. Noguchi, W. Shi, T. Tanaka, M. Matsumoto, N. Yoshida, T. Kishimoto, and S. Akira. 1997. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. USA 94: 3801-3804.
25. Levy, D. E., and J. E. Darnell, Jr. 2002. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3: 651-662.
26. Yu, H., and R. Jove. 2004. The STATs of cancer: new molecular targets come of age. Nat. Rev. Cancer 4: 97-105.
27. Bromberg, J. F., and J. E. Darnell, Jr. 1999. Potential roles of Stat1 and Stat3 in cellular transformation. Cold Spring Harb. Symp. Quant. Biol. 64: 425-428.
28. Grandis, J. R., S. D. Drenning, Q. Zeng, S. C. Watkins, M. F. Melhem, S. Endo, D. E. Johnson, L. Huang, Y. He, and J. D. Kim. 2000. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc. Natl. Acad. Sci. USA 97: 4227-4232.
29. Stahl, N., T. J. Farruggella, T. G. Boulton, Z. Zhong, J. E. J. Darnell, and G. D. Yancopoulos. 1995. Choice of STATs and other substrates by modular tyrosine-based motifs in cytokine receptors. Science 267: 1349-1353.
30. Mullersman, J. E., and L. M. Pfeffer. 1994. A novel cytoplasmic homology domain in interferon receptors. Trends Biochem. Sci. 20: 55-56.
31. Basu, L., C. H. Yang, A. Murti, J. V. Garcia, E. Croze, S. N. Constantinescu, J. E. Mullersman, and L. M. Pfeffer. 1998. The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon α/β receptor: effects on JAK-STAT activation and receptor downregulation. Virology 242: 14-21.
32. Bazan, J. F. 1990. Shared architecture of hormone binding domains in type I and II interferon receptors. Cell 61: 753-754.
33. Rani, M. R., L. Hibbert, N. Sizemore, G. R. Stark, and R. M. Ransohoff. 2002. Requirement of phosphoinositide 3-kinase and Akt for interferon-β- mediated induction of the β-R1 (SCYB11) gene. J. Biol. Chem. 277: 38456-38461.
34. Rani, M. R., G. R. Foster, S. Leung, D. Leaman, G. R. Stark, and R. M. Ransohoff. 1996. Characterization of β-R1, a gene that is selectively induced by interferon β (IFN-β) compared with IFN-α. J. Biol. Chem. 271: 22878-22884.
35. Rani, M. R., A. R. Asthagiri, A. Singh, N. Sizemore, S. S. Sathe, X. Li, J. D. DiDonato, G. R. Stark, and R. M. Ransohoff. 2001. A role for NF-κB in the induction of β-R1 by interferon-β. J. Biol. Chem. 276: 44365-44368.
36. Nadiminty, N., W. Lou, S. O. Lee, X. Lin, D. L. Trump, and A. C. Gao. 2006. Stat3 activation of NF-κB p100 processing involves CBP/p300-mediated acetylation. Proc. Natl. Acad. Sci. USA 103: 7264-7269.
37. Nguyen, H., J. Hiscott, and P. M. Pitha. 1997. The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 8: 293-312.
38. Harada, H., T. Fujita, M. Miyamoto, Y. Kimura, M. Maruyama, A. Furia, T. Miyata, and T. Taniguchi. 1989. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58: 729-739.
39. Harada, H., M. Kitagawa, N. Tanaka, H. Yamamoto, K. Harada, M. Ishihara, and T. Taniguchi. 1993. Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science 259: 971-974.