Dose-response effects of ingested carbohydrate on exercise metabolism in women

Medicine and Science in Sports and Exercise

Volumn 39, Issue 1, 2007, Pages 131-138

  Wallis, Gareth A ^a   Yeo, Sophie E ^a   Blannin, Andrew K ^a   Jeukendrup, Asker E ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Endurance exercise; Glucose ingestion; Stable isotopes; Substrate oxidation

Indexed keywords

CARBOHYDRATE; CARBON 13; CARBON DIOXIDE; GLUCOSE; GLYCOGEN;

ADULT; ARTICLE; BEVERAGE; BLOOD ANALYSIS; CALORIMETRY; CARBOHYDRATE INTAKE; CARBOHYDRATE METABOLISM; CARBON DIOXIDE EXCRETION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYCLING; ENDURANCE; EXERCISE; FEMALE; FLUID INTAKE; GLUCOSE OXIDATION; GLYCOGEN MUSCLE LEVEL; HUMAN; HUMAN EXPERIMENT; LIVER; NORMAL HUMAN; OXIDATION; SEX DIFFERENCE; TASK PERFORMANCE;

ADULT; EXERCISE TEST; FEMALE; GLUCOSE; GREAT BRITAIN; HUMANS; METABOLISM; PHYSICAL ENDURANCE;

EID: 33846205075     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/01.mss.0000241645.28467.d3     Document Type: Article

References (30)

1. BAILEY, S. P., C. M. ZACHER, and K. D. MITTLEMAN. Effect of menstrual cycle phase on carbohydrate supplementation during prolonged exercise to fatigue. J. Appl. Physiol. 88:690-697, 2000.
2. BERGSTROM, J., E. HULTMAN, L. JORFELDT, B. PERNOW, and J. WAHREN. Effect of nicotinic acid on physical working capacity and on metabolism of muscle glycogen in man. J. Appl. Physiol. 26:170-176, 1969.
3. BOSCH, A. N., S. C. DENNIS, and T. D. NOAKES. Influence of carbohydrate ingestion on fuel substrate turnover and oxidation during prolonged exercise. J. Appl. Physiol. 76:2364-2372, 1994.
4. CAMPBELL, S. E., D. J. ANGUS, and M. A. FEBBRAIO. Glucose kinetics and exercise performance during phases of the menstrual cycle: effect of glucose ingestion. Am. J. Physiol. Endocrinol. Metab. 281:E817-E825, 2001.
5. COYLE, E. F. Fluid and fuel intake during exercise. J. Sports Sci. 22:39-55, 2004.
6. COYLE, E. F., A. R. COGGAN, M. K. HEMMERT, and J. L. IVY. Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. J. Appl. Physiol. 61:165-172, 1986.
7. COYLE, E. F., A. E. JEUKENDRUP, A. J. WAGENMAKERS, and W. H. SARIS. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. Am. J. Physiol. Endocrinol. Metab. 273:E268-E275, 1997.
8. CRAIG, H. W. Isotopic standards for carbon and oxygen correction factors. Geochim. Cosmochim. Acta. 12:133-149, 1957.
9. CURRAN-EVERETT, D., and D. J. BENOS. Guidelines for reporting statistics in journals published by the American Physiological Society. Am. J. Physiol. Endocrinol. Metab. 287:E189-E191, 2004.
10. DERMAN, K. D., J. A. HAWLEY, T. D. NOAKES, and S. C. DENNIS. Fuel kinetics during intense running and cycling when fed carbohydrate. Eur. J. Appl. Physiol. Occup. Physiol. 74:36-43, 1996.
11. FLYNN, M. G., D. L. COSTILL, J. A. HAWLEY, et al. Influence of selected carbohydrate drinks on cycling performance and glycogen use. Med. Sci. Sports Exerc. 19:37-40, 1987.
12. HOROWITZ, J. F., R. MORA-RODRIGUEZ, L. O. BYERLEY, and E. F. COYLE. Substrate metabolism when subjects are fed carbohydrate during exercise. Am. J. Physiol. 276:E828-E835, 1999.
13. JEUKENDRUP, A. E. Carbohydrate intake during exercise and performance. Nutrition 20:669-677, 2004.
14. JEUKENDRUP, A. E., A. RABEN, A. GIJSEN, et al. Glucose kinetics during prolonged exercise in highly trained human subjects: effect of glucose ingestion. J. Physiol. 515:579-589, 1999.
15. JEUKENDRUP, A. E., K. VET-JOOP, A. STURK, et al. Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men. Clin. Sci. (Lond.) 98:47-55, 2000.
16. JEUKENDRUP, A. E., A. J. WAGENMAKERS, J. H. STEGEN, A. P. GIJSEN, F. BROUNS, and W. H. SARIS. Carbohydrate ingestion can completely suppress endogenous glucose production during exercise. Am. J. Physiol. 276:E672-E683, 1999.
17. JEUKENDRUP, A. E., and G. A. WALLIS. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int. J. Sports Med. 26(Suppl 1):S28-S37, 2005.
18. M'KAOUAR, H., F. PERONNET, D. MASSICOTTE, and C. LAVOIE. Gender difference in the metabolic response to prolonged exercise with [13C]glucose ingestion. Eur. J. Appl. Physiol. 92:462-469, 2004.
19. MASSICOTTE, D., F. PERONNET, E. ADOPO, G. R. BRISSON, and C. HILLAIRE-MARCEL. Effect of metabolic rate on the oxidation of ingested glucose and fructose during exercise. Int. J. Sports Med. 15:177-180, 1994.
20. MCCONELL, G., S. FABRIS, J. PROIETTO, and M. HARGREAVES. Effect of carbohydrate ingestion on glucose kinetics during exercise. J. Appl. Physiol. 77:1537-1541, 1994.
21. PALLIKARAKIS, N., N. SPHIRIS, and P. LEFEBVRE. Influence of the bicarbonate pool and on the occurrence of 13CO2 in exhaled air. Eur. J. Appl. Physiol. Occup. Physiol. 63:179-183, 1991.
22. PICKERT, A., D. OVERKAMP, W. RENN, H. LIEBICH, and M. EGGSTEIN. Selected ion monitoring gas chromatography/mass spectrometry using uniformly labelled (13C)glucose for determination of glucose turnover in man. Biol. Mass Spectrom. 20:203-209, 1991.
23. PIRNAY, F., M. LACROIX, F. MOSORA, A. LUYCKX, and P. LEFEBVRE. Effect of glucose ingestion on energy substrate utilization during prolonged muscular exercise. Eur. J. Appl. Physiol. Occup. Physiol. 36:247-254, 1977.
24. RIDDELL, M. C., S. L. PARTINGTON, N. STUPKA, D. ARMSTRONG, C. RENNIE, and M. A. TARNOPOLSKY. Substrate utilization during exercise performed with and without glucose ingestion in female and male endurance trained athletes. Int. J. Sport Nutr. Exerc. Metab. 13:407-421, 2003.
25. ROBERT, J. J., J. KOZIET, D. CHAUVET, D. DARMAUN, J. F. DESJEUX, and V. R. YOUNG. Use of 13C-labeled glucose for estimating glucose oxidation: some design considerations. J. Appl. Physiol. 63:1725-1732, 1987.
26. TARNOPOLSKY, M. A. Gender differences in substrate metabolism during endurance exercise. Can. J. Appl. Physiol. 25:312-327, 2000.
27. TSINTZAS, O. K., C. WILLIAMS, L. BOOBIS, and P. GREENHAFF. Carbohydrate ingestion and glycogen utilization in different muscle fibre types in man. J. Physiol. (Lond.) 489:243-250, 1995.
28. WAGENMAKERS, A. J., F. BROUNS, W. H. SARIS, and D. HALLIDAY. Oxidation rates of orally ingested carbohydrates during prolonged exercise in men. J. Appl. Physiol. 75:2774-2780, 1993.
29. WALLIS, G. A., R. DAWSON, J. ACHTEN, J. WEBBER, and A. E. JEUKENDRUP. Metabolic response to carbohydrate ingestion during exercise in males and females. Am. J. Physiol. Endocrinol. Metab. 290:E708-E715, 2006.
30. WATT, M. J., K. F. HOWLETT, M. A. FEBBRAIO, L. L. SPRIET, and M. HARGREAVES. Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans. J. Physiol. (Lond.) 534:269-278, 2001.