Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo

Journal of Immunology

Volumn 178, Issue 2, 2007, Pages 1199-1207

  Harris, James E ^a   Nuttall, Robert K ^b   Elkington, Paul T ^a   Green, Justin A ^a   Horncastle, Donna E ^a   Graeber, Manuel B ^a   Edwards, Dylan R ^b   Friedland, Jon S ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GELATINASE A; GELATINASE B; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; STROMELYSIN; SYNAPTOTAGMIN I; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ARTICLE; ASTROCYTE; BRAIN BIOPSY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUBERCULOSIS; TUBERCULOUS MENINGITIS;

EID: 33846186853     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.2.1199     Document Type: Article

References (49)

1. Zuger, A., and F. Lowy. 1995. Tuberculosis of the Brain, Meninges and Spinal Cord. Little. Brown, Boston.
2. Thwaites, G. E., and T. T. Hien. 2005. Tuberculous meningitis: many questions, too few answers. Lancet Neurol. 4: 160-170.
3. Thwaites, G. E., C. P. Simmons, N. Than Ha Quyen, T. Thi Hong Chau, P. Phuong Mai, N. Thi Dung, N. Hoan Phu, N. P. White, T. Tinh Hien. and J. J. Farrar. 2003. Pathophysiology and prognosis in Vietnamese adults with tuberculous meningitis. J. Infect. Dis. 188: 1105-1115.
4. Goetzl, E. J., M. J. Banda, and D. Leppert. 1996. Matrix metalloproteinases in immunity. J. Immunol. 156: 1-4.
5. Elkington, P. T., C. M. O'Kane, and J. S. Friedland. 2005. The paradox of matrix metalloproteinases in infectious disease. Clin. Exp. Immunol. 142: 12-20.
6. Rivera, S., J. Jourquin, C. Ogier, A. Bernard, G. Charton, E. Tremblay, and M. Khrestchatisky. 2004. [The MMP/TIMP system in the nervous system]. Med. Sci. 20: 55-60.
7. Cuzner, M. L., D. Gveric, C. Strand, A. J. Loughlin, L. Paemen, G. Opdenakker, and J. Newcombe. 1996. The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. J. Neuropathol. Exp. Neurol. 55: 1194-1204.
8. Weaver, A., A. Goncalves da Silva, R. K. Nuttall, D. R. Edwards, S. D. Shapiro, S. Rivest, and V. W. Yong. 2005. An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. FASEB J. 19: 1668-1670.
9. Brinckerhoff, C. E., and L. M. Matrisian. 2002. Matrix metalloproteinases: a tail of a frog that became a prince. Nat. Rev. Mol. Cell Biol. 3: 207-214.
10. Asahi, M., X. Wang, T. Mori, T. Sumii, J. C. Jung, M. A. Moskowitz, M. E. Fini, and E. H. Lo. 2001. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J. Neurosci. 21: 7724-7732.
11. Matsuura, E., F. Umehara, T. Hashiguchi, N. Fujimoto, Y. Okada, and M. Osame. 2000. Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis. J. Neurol. Sci. 173: 45-52.
12. Price, N. M., J. Farrar, T. T. Tran, T. H. Nguyen, T. H. Tran, and J. S. Friedland. 2001. Identification of a matrix-degrading phenotype in human tuberculosis in vitro and in vivo. J. Immunol. 166: 4223-4230.
13. Andela, V. B., E. M. Schwarz, J. E. Puzas, R. J. O'Keefe, and R. N. Rosier. 2000. Tumor metastasis and the reciprocal regulation of prometastatic and antimetastatic factors by nuclear factor κB. Cancer Res. 60: 6557-6562.
14. Wickremasinghe, M. I., L. H. Thomas, and J. S. Friedland. 1999. Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-κB-dependent network. J. Immunol 163: 3936-3947.
15. Sato, H., and M. Seiki. 1993. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8: 395-405.
16. Ghosh, S., M. J. May, and E. B. Kopp. 1998. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16: 225-260.
17. Svendsen, C. N. 2002. The amazing astrocyte. Nature 417: 29-32.
18. Uhm, J. H., N. P. Dooley, L. Y. Oh, and V. W. Yong. 1998. Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix. Glia 22: 53-63.
19. Yong, V. W. 1999. The potential use of MMP inhibitors to treat CNS diseases. Expert Opin. Investig. Drugs 8: 255-268.
20. Zhang, X., M. Cheng, and S. K. Chintala. 2004. Optic nerve ligation leads to astrocyte-associated matrix metalloproteinase-9 induction in the mouse retina. Neurosci. Lett. 356: 140-144.
21. Kurisaki, H. 2000. [Central nervous system tuberculosis with and without HIV infection-clinical, neuroimaging, and neuropathological study]. Rinsho Shinkeigaku 40: 209-217.
22. Hickey, W. F. 2001. Basic principles of immunological surveillance of the normal central nervous system. Glia 36; 118-124.
23. Elkington, P. T., J. A. Green, and J. S. Friedland. 2006. Filter sterilization of highly infectious samples to prevent false negative analysis of matrix metalloproteinase activity. J. Immunol. Methods 309: 115-119.
24. Elkington, P. T., R. K. Nuttall, J. J. Boyle, C. M. O'Kane, D. E. Horncastle, D. R. Edwards, and J. S. Friedland. 2005. Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1. Am. J. Respir. Crit. Care Med. 172: 1596-1604.
25. Nuttall, R. K., C. J. Pennington, J. Taplin, A. Wheal, V. W. Yong, P. A. Forsyth, and D. R. Edwards. 2003. Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells. Mol. Cancer Res. 1: 333-345.
26. Leber, T. M., and F. R. Balkwill. 1997. Zymography: a single-step staining method for quantitation of proteolytic activity on substrate gels. Anal. Biochem. 249: 24-28.
27. Lyss, G., A. Knorre, T. J. Schmidt, H. L. Pahl, and I. Merfort. 1998. The antiinflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κA by directly targeting p65. J. Biol Chem. 273: 33508-33516.
28. Simmons, C. P., G. E. Thwaites, N. T. Quyen, T. T. Chau, P. P. Mai, N. T. Dung, K. Stepniewska, N. J. White, T. T. Hien, and J. Farrar. 2005. The clinical benefit of adjunctive dexamethasone in tuberculous meningitis is not associated with measurable attenuation of peripheral or local immune responses. J. Immunol. 175: 579-590.
29. Coussens, L. M., C. L. Tinkle, D. Hanahan, and Z. Werb. 2000. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103: 481-490.
30. Opdenakker, G., I. Nelissen, and J. Van Damme. 2003. Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis. Lancet Neurol. 2: 747-756.
31. Lee, K. Y., E. H. Kim, W. S. Yang, H. Ryu, S. N. Cho, B. I. Lee, and J. H. Heo. 2004. Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis. J. Neurol. Sci. 220: 73-78.
32. Becher, B., A. Prat, and J. P. Antel. 2000. Brain-immune connection: immunoregulatory properties of CNS-resident cells. Glia 29: 293-304.
33. Babcock, A. A., W. A. Kuziel, S. Rivest, and T. Owens. 2003. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J. Neurosci. 23: 7922-7930.
34. Newman, T. A., S. T. Woolley, P. M. Hughes, N. R. Sibson, D. C. Anthony, and V. H. Perry. 2001. T-cell- and macrophage-mediated axon damage in trie absence of a CNS-specific immune response: involvement of metalloproteinases. Brain 124: 2203-2214.
35. Bsibsi, M., R. Ravid, D. Gveric, and J. M. Van Noort. 2002. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neural. 61: 1013-1021.
36. Quesniaux, V., C. Fremond, M. Jacobs, S. Parida, D. Nicolle, V. Yeremeev, F. Bihl, F. Erard, T. Botha, and M. Drennan. 2004. Toll-like receptor pathways in the immune responses to mycobacteria. Microbes Infect. 6: 946-959.
37. Vos, C. M., L. Sjulson, A. Nath, J. C. McArthur, C. A. Pardo, J. Rothstein, and K. Conant. 2000. Cytotoxicity by matrix metalloprotease-1 in organotypic spinal cord and dissociated neuronal cultures. Exp. Neurol. 163: 324-330.
38. Conant, K., C. St Hiliaire, H. Nagase, R. Visse, D. Gary, N. Haughey, C. Anderson, J. Turchan, and A. Nath. 2004. Matrix metalloproteinase 1 interacts with neuronal integrins and stimulates dephosphorylation of Akt. J. Biol Chem. 279: 8056-8062.
39. Itoh, Y., M. Kajita, H. Kinoh, H. Mori, A. Okada, and M. Seiki. 1999. Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase. J. Biol. Chem. 274: 34260-34266.
40. Graeber, M. B., and W. J. Streit. 1990. Microglia: immune network in the CNS. Brain Pathol. 1: 2-5.
41. Rock, R. B., S. Hu, G. Gekker, W. S. Sheng, B. May, V. Kapur, and P. K. Peterson. 2005. Mycobacterium tuberculosis-induced cytokine and chemokine expression by human microglia and astrocytes: effects of dexamethasone. J. Infect. Dis. 192: 2054-2058.
42. Cunningham, L. A., M. Wetzel, and G. A. Rosenberg. 2005. Multiple roles for MMPs and TIMPs in cerebral ischemia. Glia 50: 329-339.
43. Yoshizaki, T., H. Sato, and M. Furukawa. 2002. Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic research to clinical implication (review). Oncol. Rep. 9: 607-611.
44. Ganchi, P. A., S. C Sun, W. C. Greene, and D. W. Ballard. 1993. A novel NF-κB complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Mol Cell Biol 13: 7826-7835.
45. Bassett, S. E., S. M. Fennewald, D. J. King, X. Li, N. K. Herzog, R. Shope, J. F. Aronson, B. A. Luxon, and D. G. Gorenstein. 2004. Combinatorial selection and edited combinatorial selection of phosphorothioate aptamers targeting human nuclear factor-κB RelA/p50 and RelA/RelA. Biochemistry 43: 9105-9115.
46. Krappmann, D., and C. Scheidereit. 1997. Regulation of NF-κB activity by IκBα and IκBβ stability. Immunobiology 198: 3-13.
47. Li, Q., and I. M. Verma. 2002. NF-κB regulation in the immune system. Nat. Rev. Immunol 2: 725-734.
48. Rungeler, P., G. Lyss, V. Castro, G. Mora, H. L. Pahl, and I. Merfort. 1998. Study of three sesquiterpene lactones from Tithonia diversifolia on their antiinflammatory activity using the transcription factor NF-κB and enzymes of the arachidonic acid pathway as targets. Planta Med. 64: 588-593.
49. Thwaites, G. E., D. B. Nguyen, H. D. Nguyen, T. Q. Hoang, T. T. Do, T. C. Nguyen, Q. H. Nguyen, T. T. Nguyen, N. H. Nguyen, T. N. Nguyen, et al. 2004. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N. Engl. J. Med. 351: 1741-1751.