Dactinomycin impairs cellular respiration and reduces accompanying ATP formation

Molecular Pharmaceutics

Volumn 3, Issue 6, 2006, Pages 762-772

  Tao, Zhimin ^a   Ahmad, Syed S ^b   Penefsky, Harvey S ^c   Goodisman, Jerry ^a   Souid, Abdul Kader ^b  

^a SYRACUSE UNIVERSITY   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

k, zero order rate constant for cellular oxygen consumption; Pd phosphor, palladium derivative of meso tetra (4 sulfonatophenyl) tetrabenzoporphyrin; zVAD fmk, benzyloxycarbonyl val ala asp fluoromethyl ketone

Indexed keywords

ADENOSINE TRIPHOSPHATE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CYANIDE; DACTINOMYCIN; DIMETHYL SULFOXIDE; DOXORUBICIN; LUCIFERASE; LUCIFERIN;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CELL RESPIRATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MINIMUM INHIBITORY CONCENTRATION; MITOCHONDRIAL RESPIRATION; OXYGEN CONSUMPTION; PHOSPHORESCENCE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CELL RESPIRATION; DACTINOMYCIN; DOXORUBICIN; DRUG COMBINATIONS; DRUG SYNERGISM; HL-60 CELLS; HUMANS; JURKAT CELLS; MITOCHONDRIA; OXYGEN CONSUMPTION;

EID: 33846168792     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp0600485     Document Type: Article

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