메뉴 건너뛰기




Volumn 353, Issue 4, 2007, Pages 1056-1062

Processing of nerve growth factor: The role of basic amino acid clusters in the pro-region

Author keywords

Basic amino acid clusters; Furin; Nerve growth factor (NGF); Propeptide; Protein processing

Indexed keywords

AMINO ACID; FURIN; NERVE GROWTH FACTOR; NEUROTROPHIN; PEPTIDE; PRONEUROTROPHIN; UNCLASSIFIED DRUG;

EID: 33846126878     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.12.136     Document Type: Article
Times cited : (14)

References (25)
  • 1
    • 0023888321 scopus 로고
    • Processing of the native nerve growth factor:precursor to form biologically active nerve growth factor
    • Edwards R.H., Selby M.J., Garcia P.D., and Rutter W.J. Processing of the native nerve growth factor:precursor to form biologically active nerve growth factor. J. Biol. Chem. 263 (1988) 6810-6815
    • (1988) J. Biol. Chem. , vol.263 , pp. 6810-6815
    • Edwards, R.H.1    Selby, M.J.2    Garcia, P.D.3    Rutter, W.J.4
  • 2
    • 0024027151 scopus 로고
    • Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector
    • Edwards R.H., Selby M.J., Mobley W.C., Weinrich S.L., Hruby D.E., and Rutter W.J. Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector. Mol. Cell Biol. 8 (1988) 2456-2464
    • (1988) Mol. Cell Biol. , vol.8 , pp. 2456-2464
    • Edwards, R.H.1    Selby, M.J.2    Mobley, W.C.3    Weinrich, S.L.4    Hruby, D.E.5    Rutter, W.J.6
  • 4
    • 0030050741 scopus 로고    scopus 로고
    • Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases
    • Seidah N.G., Benjannet S., Pareek S., Chretien M., and Murphy R.A. Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases. FEBS. Lett. 379 (1996) 247-250
    • (1996) FEBS. Lett. , vol.379 , pp. 247-250
    • Seidah, N.G.1    Benjannet, S.2    Pareek, S.3    Chretien, M.4    Murphy, R.A.5
  • 6
    • 0029074694 scopus 로고
    • Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway
    • Blochl A., and Thoenen H. Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur. J. Neurosci. 7 (1995) 1220-1228
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1220-1228
    • Blochl, A.1    Thoenen, H.2
  • 7
    • 0029845927 scopus 로고    scopus 로고
    • The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells
    • Heymach Jr. J.V., Kruttgen A., Suter U., and Shooter E.M. The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells. J. Biol. Chem. 271 (1996) 25430-25470
    • (1996) J. Biol. Chem. , vol.271 , pp. 25430-25470
    • Heymach Jr., J.V.1    Kruttgen, A.2    Suter, U.3    Shooter, E.M.4
  • 8
    • 0343267775 scopus 로고    scopus 로고
    • Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons
    • Blochl A., and Thoenen H. Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons. Mol. Cell Neurosci. 7 (1996) 173-190
    • (1996) Mol. Cell Neurosci. , vol.7 , pp. 173-190
    • Blochl, A.1    Thoenen, H.2
  • 9
    • 0034090874 scopus 로고    scopus 로고
    • Balance of two secretion pathways of nerve growth factor in PC12 cells changes during the progression of their differentiation, with a decrease in constitutive secretion in more differentiated cells
    • Nomoto H., Tomotoshi K., Ito H., and Furukawa S. Balance of two secretion pathways of nerve growth factor in PC12 cells changes during the progression of their differentiation, with a decrease in constitutive secretion in more differentiated cells. J. Neurosci. Res. 59 (2000) 632-642
    • (2000) J. Neurosci. Res. , vol.59 , pp. 632-642
    • Nomoto, H.1    Tomotoshi, K.2    Ito, H.3    Furukawa, S.4
  • 10
    • 0034212624 scopus 로고    scopus 로고
    • Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor
    • Farhadi H.F., Mowla S.J., Petrecca K., Morris S.J., Seidah N.G., and Murphy R.A. Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor. J. Neurosci. 20 (2000) 4059-4068
    • (2000) J. Neurosci. , vol.20 , pp. 4059-4068
    • Farhadi, H.F.1    Mowla, S.J.2    Petrecca, K.3    Morris, S.J.4    Seidah, N.G.5    Murphy, R.A.6
  • 11
    • 0035918236 scopus 로고    scopus 로고
    • Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor
    • Mowla S.J., Farhadi H.F., Pareek S., Atwal J.K., Morris S.J., Seidah N.G., and Murphy R.A. Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor. J. Biol. Chem. 276 (2001) 12660-12666
    • (2001) J. Biol. Chem. , vol.276 , pp. 12660-12666
    • Mowla, S.J.1    Farhadi, H.F.2    Pareek, S.3    Atwal, J.K.4    Morris, S.J.5    Seidah, N.G.6    Murphy, R.A.7
  • 12
    • 0042886033 scopus 로고    scopus 로고
    • Sympathetic neurons synthesize and secrete pro-nerve growth factor protein
    • Hasan W., Pedchenko T., Krizsan-Agbas D., Baum L., and Smith P.G. Sympathetic neurons synthesize and secrete pro-nerve growth factor protein. J. Neurobiol. 57 (2003) 38-53
    • (2003) J. Neurobiol. , vol.57 , pp. 38-53
    • Hasan, W.1    Pedchenko, T.2    Krizsan-Agbas, D.3    Baum, L.4    Smith, P.G.5
  • 13
    • 18044362926 scopus 로고    scopus 로고
    • `Mature' nerve growth factor is a minor species in most peripheral tissues
    • Bierl M.A., Jones E.E., Crutcher K.A., and Isaacson L.G. `Mature' nerve growth factor is a minor species in most peripheral tissues. Neurosci. Lett. 380 (2005) 133-1337
    • (2005) Neurosci. Lett. , vol.380 , pp. 133-1337
    • Bierl, M.A.1    Jones, E.E.2    Crutcher, K.A.3    Isaacson, L.G.4
  • 14
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R., Kermani P., Teng K.K., and Hempstead B.L. Regulation of cell survival by secreted proneurotrophins. Science 294 (2001) 1945-1948
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 15
    • 0034848604 scopus 로고    scopus 로고
    • The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
    • Fahnestock M., Michalski B., Xu B., and Coughlin M.D. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol. Cell Neurosci. 18 (2001) 210-220
    • (2001) Mol. Cell Neurosci. , vol.18 , pp. 210-220
    • Fahnestock, M.1    Michalski, B.2    Xu, B.3    Coughlin, M.D.4
  • 16
    • 2942536284 scopus 로고    scopus 로고
    • Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease
    • Peng S., Wuu J., Mufson E.J., and Fahnestock M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J. Neuropathol. Exp. Neurol. 63 (2004) 641-649
    • (2004) J. Neuropathol. Exp. Neurol. , vol.63 , pp. 641-649
    • Peng, S.1    Wuu, J.2    Mufson, E.J.3    Fahnestock, M.4
  • 20
    • 2042465006 scopus 로고    scopus 로고
    • The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor
    • Fahnestock M., Yu G., Michalski B., Mathew S., Colquhoun A., Ross G.M., and Coughlin M.D. The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor. J. Neurochem. 89 (2004) 581-592
    • (2004) J. Neurochem. , vol.89 , pp. 581-592
    • Fahnestock, M.1    Yu, G.2    Michalski, B.3    Mathew, S.4    Colquhoun, A.5    Ross, G.M.6    Coughlin, M.D.7
  • 22
    • 0034662681 scopus 로고    scopus 로고
    • Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis
    • Sawano A., and Miyawaki A. Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis. Nucleic Acids Res. 28 (2000) E78
    • (2000) Nucleic Acids Res. , vol.28
    • Sawano, A.1    Miyawaki, A.2
  • 23
    • 0025614095 scopus 로고
    • Highly sensitive enzyme immunoassay for beta-nerve growth factor (NGF): a tool for measurement of NGF level in rat serum
    • Murase K., Takeuchi R., Furukawa S., Furukawa Y., and Hayashi K. Highly sensitive enzyme immunoassay for beta-nerve growth factor (NGF): a tool for measurement of NGF level in rat serum. Biochem. Int. 22 (1990) 807-813
    • (1990) Biochem. Int. , vol.22 , pp. 807-813
    • Murase, K.1    Takeuchi, R.2    Furukawa, S.3    Furukawa, Y.4    Hayashi, K.5
  • 25
    • 0033607676 scopus 로고    scopus 로고
    • The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity
    • Zhong M., Munzer J.S., Basak A., Benjannet S., Mowla S.J., Decroly E., Chretien M., and Seidah N.G. The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity. J. Biol. Chem. 274 (1999) 33913-33920
    • (1999) J. Biol. Chem. , vol.274 , pp. 33913-33920
    • Zhong, M.1    Munzer, J.S.2    Basak, A.3    Benjannet, S.4    Mowla, S.J.5    Decroly, E.6    Chretien, M.7    Seidah, N.G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.