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Volumn 18, Issue 2, 2007, Pages 201-210

Potential for bone turnover markers to cost-effectively identify and select post-menopausal osteopenic women at high risk of fracture for bisphosphonate therapy

Author keywords

Bisphosphonates; Bone turnover; Cost effectiveness; Non vertebral fracture; Vertebral fracture

Indexed keywords

ALENDRONIC ACID; BIOLOGICAL MARKER; BISPHOSPHONIC ACID DERIVATIVE;

EID: 33846124899     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-006-0218-7     Document Type: Article
Times cited : (48)

References (47)
  • 1
    • 0142091169 scopus 로고    scopus 로고
    • Adverse outcomes of osteoporotic fractures in the general population
    • Melton LJ III (2003) Adverse outcomes of osteoporotic fractures in the general population. J Bone Miner Res 18(6):1139-1141
    • (2003) J Bone Miner Res , vol.18 , Issue.6 , pp. 1139-1141
    • Melton III, L.J.1
  • 2
    • 0034530951 scopus 로고    scopus 로고
    • Fracture risk reduction with alendronate in women with osteoporosis: The fracture intervention trial. FIT Research Group
    • Black DM, Thompson DE, Bauer DC et al (2000) Fracture risk reduction with alendronate in women with osteoporosis: the fracture intervention trial. FIT Research Group. J Clin Endocrinol Metab 85(11):4118-4124
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.11 , pp. 4118-4124
    • Black, D.M.1    Thompson, D.E.2    Bauer, D.C.3
  • 4
    • 0035852034 scopus 로고    scopus 로고
    • Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: Results from the National Osteoporosis Risk Assessment
    • Siris ES, Miller PD, Barrett-Connor E et al (2001) Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment. JAMA 286(22):2815-2822
    • (2001) JAMA , vol.286 , Issue.22 , pp. 2815-2822
    • Siris, E.S.1    Miller, P.D.2    Barrett-Connor, E.3
  • 5
    • 17844408127 scopus 로고    scopus 로고
    • Cost-effectiveness of alendronate therapy for osteopenic postmenopausal women
    • Schousboe JT, Nyman JA, Kane RL et al (2005) Cost-effectiveness of alendronate therapy for osteopenic postmenopausal women. Ann Intern Med 142(9):734-741
    • (2005) Ann Intern Med , vol.142 , Issue.9 , pp. 734-741
    • Schousboe, J.T.1    Nyman, J.A.2    Kane, R.L.3
  • 6
    • 0033982356 scopus 로고    scopus 로고
    • Serum bone alkaline phosphatase and calcaneus bone density predict fractures: A prospective study
    • Ross PD, Kress BC, Parson RE, Wasnich RD et al (2000) Serum bone alkaline phosphatase and calcaneus bone density predict fractures: a prospective study. Osteoporos Int 11(1):76-82
    • (2000) Osteoporos Int , vol.11 , Issue.1 , pp. 76-82
    • Ross, P.D.1    Kress, B.C.2    Parson, R.E.3    Wasnich, R.D.4
  • 7
    • 13244296806 scopus 로고    scopus 로고
    • Risk factors for hip fracture in women with high BMD: EPIDOS study
    • Robbins JA, Schott AM, Garnero P et al (2005) Risk factors for hip fracture in women with high BMD: EPIDOS study. Osteoporos Int 16(2):149-154
    • (2005) Osteoporos Int , vol.16 , Issue.2 , pp. 149-154
    • Robbins, J.A.1    Schott, A.M.2    Garnero, P.3
  • 8
    • 0033926478 scopus 로고    scopus 로고
    • Serum type I collagen breakdown product (serum CTX) predicts hip fracture risk in elderly women: The EPIDOS study
    • Chapurlat RD, Garnero P, Breart G et al (2000) Serum type I collagen breakdown product (serum CTX) predicts hip fracture risk in elderly women: the EPIDOS study. Bone 27(2):283-286
    • (2000) Bone , vol.27 , Issue.2 , pp. 283-286
    • Chapurlat, R.D.1    Garnero, P.2    Breart, G.3
  • 9
    • 10144251796 scopus 로고    scopus 로고
    • Markers of bone resorption predict hip fracture in elderly women: The EPIDOS Prospective Study
    • Garnero P, Hausherr E, Chapuy MC et al (1996) Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study. J Bone Miner Res 11(10):1531-1538
    • (1996) J Bone Miner Res , vol.11 , Issue.10 , pp. 1531-1538
    • Garnero, P.1    Hausherr, E.2    Chapuy, M.C.3
  • 10
    • 0343517092 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: The OFELY study
    • Aug
    • Garnero P, Sornay-Rendu E, Claustrat B et al (2000) Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study. J Bone Miner Res 15(8):1526-1536. Aug 2000
    • (2000) J Bone Miner Res , vol.15 , Issue.8 , pp. 1526-1536
    • Garnero, P.1    Sornay-Rendu, E.2    Claustrat, B.3
  • 11
    • 2942730031 scopus 로고    scopus 로고
    • Biochemical markers of bone metabolism and prediction of fracture in elderly women
    • Gerdhem P, Ivaska KK, Alatalo SL et al (2004) Biochemical markers of bone metabolism and prediction of fracture in elderly women. J Bone Miner Res 19(3):386-393
    • (2004) J Bone Miner Res , vol.19 , Issue.3 , pp. 386-393
    • Gerdhem, P.1    Ivaska, K.K.2    Alatalo, S.L.3
  • 12
    • 0027772390 scopus 로고
    • Markov models in medical decision making: A practical guide
    • Sonnenberg FA, Beck JR (1993)Markov models in medical decision making: a practical guide. Med Decis Making 13(4):322-338
    • (1993) Med Decis Making , vol.13 , Issue.4 , pp. 322-338
    • Sonnenberg, F.A.1    Beck, J.R.2
  • 13
    • 0032978718 scopus 로고    scopus 로고
    • Fracture incidence in Olmsted County, Minnesota: Comparison of urban with rural rates and changes in urban rates over time
    • Melton LJ III, Crowson CS, O'Fallon WM (1999) Fracture incidence in Olmsted County, Minnesota: comparison of urban with rural rates and changes in urban rates over time. Osteoporos Int 9(1):29-37
    • (1999) Osteoporos Int , vol.9 , Issue.1 , pp. 29-37
    • Melton III, L.J.1    Crowson, C.S.2    O'Fallon, W.M.3
  • 14
    • 0030098039 scopus 로고    scopus 로고
    • History of the Rochester epidemiology project
    • Melton LJ III (1996) History of the Rochester epidemiology project. Mayo Clin Proc 71(3):266-274
    • (1996) Mayo Clin Proc , vol.71 , Issue.3 , pp. 266-274
    • Melton III, L.J.1
  • 15
    • 0030786934 scopus 로고    scopus 로고
    • Bone density and risk of hip fracture in men and women: Cross sectional analysis
    • De Laet CE, van Hout BA, Burger H et al (1997) Bone density and risk of hip fracture in men and women: cross sectional analysis. BMJ 315(7102):221-225
    • (1997) BMJ , vol.315 , Issue.7102 , pp. 221-225
    • De Laet, C.E.1    van Hout, B.A.2    Burger, H.3
  • 16
    • 0031765564 scopus 로고    scopus 로고
    • Updated data on proximal femur bone mineral levels of US adults
    • Looker AC, Wahner HW, Dunn WL et al (1998) Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int 8(5):468-489
    • (1998) Osteoporos Int , vol.8 , Issue.5 , pp. 468-489
    • Looker, A.C.1    Wahner, H.W.2    Dunn, W.L.3
  • 17
    • 0029986509 scopus 로고    scopus 로고
    • Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures
    • Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312(7041):1254-1259
    • (1996) BMJ , vol.312 , Issue.7041 , pp. 1254-1259
    • Marshall, D.1    Johnell, O.2    Wedel, H.3
  • 18
    • 0032951747 scopus 로고    scopus 로고
    • Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures. Study of Osteoporotic Fractures Research Group
    • Black DM, Arden NK, Palermo L et al (1999) Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures. Study of Osteoporotic Fractures Research Group. J Bone Miner Res 14(5):821-828
    • (1999) J Bone Miner Res , vol.14 , Issue.5 , pp. 821-828
    • Black, D.M.1    Arden, N.K.2    Palermo, L.3
  • 20
    • 0032795956 scopus 로고    scopus 로고
    • Forearm fractures as predictors of subsequent osteoporotic fractures
    • Cuddihy MT, Gabriel SE, Crowson CS et al (1999) Forearm fractures as predictors of subsequent osteoporotic fractures. Osteoporos Int 9(6):469-475
    • (1999) Osteoporos Int , vol.9 , Issue.6 , pp. 469-475
    • Cuddihy, M.T.1    Gabriel, S.E.2    Crowson, C.S.3
  • 21
    • 0032583492 scopus 로고    scopus 로고
    • Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: Results from the fracture intervention trial
    • Cummings SR, Black DM, Thompson DE et al (1998) Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the fracture intervention trial. JAMA 280(24):2077-2082
    • (1998) JAMA , vol.280 , Issue.24 , pp. 2077-2082
    • Cummings, S.R.1    Black, D.M.2    Thompson, D.E.3
  • 22
    • 14644402372 scopus 로고    scopus 로고
    • Effect of alendronate on vertebral fracture risk in women with bone mineral density T scores of-1.6 to -2.5 at the femoral neck: The fracture intervention trial
    • Quandt SA, Thompson DE, Schneider DL et al (2005) Effect of alendronate on vertebral fracture risk in women with bone mineral density T scores of-1.6 to -2.5 at the femoral neck: the fracture intervention trial. Mayo Clin Proc 80(3):343-349
    • (2005) Mayo Clin Proc , vol.80 , Issue.3 , pp. 343-349
    • Quandt, S.A.1    Thompson, D.E.2    Schneider, D.L.3
  • 23
    • 33144489593 scopus 로고    scopus 로고
    • Pre-treatment levels of bone turnover and the antifracture efficacy of alendronate: The fracture intervention trial
    • Bauer DC, Garnero P, Hochberg MC et al (2006) Pre-treatment levels of bone turnover and the antifracture efficacy of alendronate: the fracture intervention trial. J Bone Miner Res 21(2):292-299
    • (2006) J Bone Miner Res , vol.21 , Issue.2 , pp. 292-299
    • Bauer, D.C.1    Garnero, P.2    Hochberg, M.C.3
  • 24
    • 0035178263 scopus 로고    scopus 로고
    • Challenges for model-based economic evaluations of postmenopausal osteoporosis interventions
    • Tosteson AN, Jonsson B, Grima DT et al (2001) Challenges for model-based economic evaluations of postmenopausal osteoporosis interventions. Osteoporos Int 12(10):849-857
    • (2001) Osteoporos Int , vol.12 , Issue.10 , pp. 849-857
    • Tosteson, A.N.1    Jonsson, B.2    Grima, D.T.3
  • 26
    • 1242335072 scopus 로고    scopus 로고
    • The components of excess mortality after hip fracture
    • Kanis JA, Oden A, Johnell O et al (2003) The components of excess mortality after hip fracture. Bone 32(5):468-473
    • (2003) Bone , vol.32 , Issue.5 , pp. 468-473
    • Kanis, J.A.1    Oden, A.2    Johnell, O.3
  • 27
    • 1342268230 scopus 로고    scopus 로고
    • Mortality after osteoporotic fractures
    • Johnell O, Kanis JA, Oden A et al (2004) Mortality after osteoporotic fractures. Osteoporos Int 15(1):38-42
    • (2004) Osteoporos Int , vol.15 , Issue.1 , pp. 38-42
    • Johnell, O.1    Kanis, J.A.2    Oden, A.3
  • 28
    • 1342310684 scopus 로고    scopus 로고
    • The risk and burden of vertebral fractures in Sweden
    • Jan
    • Kanis JA, Johnell O, Oden A et al (2004) The risk and burden of vertebral fractures in Sweden. Osteoporos Int 15(1):20-26. Jan
    • (2004) Osteoporos Int , vol.15 , Issue.1 , pp. 20-26
    • Kanis, J.A.1    Johnell, O.2    Oden, A.3
  • 29
    • 33846165618 scopus 로고    scopus 로고
    • Drug Topics 2001 Red Book (2001) Montvale, Medical Economics Co, New Jersey
    • Drug Topics 2001 Red Book (2001) Montvale, Medical Economics Co, New Jersey
  • 30
    • 0036245299 scopus 로고    scopus 로고
    • Direct medical costs attributable to osteoporotic fractures
    • Gabriel SE, Tosteson AN, Leibson CL et al (2002) Direct medical costs attributable to osteoporotic fractures. Osteoporos Int 13(4):323-330
    • (2002) Osteoporos Int , vol.13 , Issue.4 , pp. 323-330
    • Gabriel, S.E.1    Tosteson, A.N.2    Leibson, C.L.3
  • 31
    • 33846155070 scopus 로고    scopus 로고
    • Centers for Medicare and Medicaid Services. Available at:, Accessed August 12, 2003
    • Centers for Medicare and Medicaid Services. Available at: http://cms.hhs.gov/providers/pufdownload/rvudown.asp. Accessed August 12, 2003
  • 32
    • 0036799693 scopus 로고    scopus 로고
    • Mortality, disability, and nursing home use for persons with and without hip fracture: A population-based study
    • Leibson CL, Tosteson AN, Gabriel SE et al (2002) Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study. J Am Geriatr Soc 50(10):1644-1650
    • (2002) J Am Geriatr Soc , vol.50 , Issue.10 , pp. 1644-1650
    • Leibson, C.L.1    Tosteson, A.N.2    Gabriel, S.E.3
  • 33
    • 4143094414 scopus 로고    scopus 로고
    • Agency for Healthcare Research and Quality, Available at:, Accessed August 12
    • Agency for Healthcare Research and Quality. Medical Expenditure Panel Survey. Available at: http://www.meps.ahrq.gov/. Accessed August 12, 2003
    • (2003) Medical Expenditure Panel Survey
  • 34
    • 0842278685 scopus 로고    scopus 로고
    • Distribution and determinants of health and work status in a comprehensive population of injury patients
    • Meerding WJ, Looman CW, Essink-Bot ML et al (2004) Distribution and determinants of health and work status in a comprehensive population of injury patients. J Trauma 56(1):150-161
    • (2004) J Trauma , vol.56 , Issue.1 , pp. 150-161
    • Meerding, W.J.1    Looman, C.W.2    Essink-Bot, M.L.3
  • 35
    • 33846125750 scopus 로고    scopus 로고
    • U.S. Census Bureau, Bureau of Labor Statistics, Available at:, Accessed May 28
    • U.S. Census Bureau, Bureau of Labor Statistics. CPS Annual Demographic Survey. Available at: http://ferret.bls.census.gov/macro/032002/perinc/ new05_000.htm. Accessed May 28, 2004
    • (2004) CPS Annual Demographic Survey
  • 36
    • 33846128275 scopus 로고    scopus 로고
    • U.S. Census Bureau, Available at:, Accessed May 28
    • U.S. Census Bureau. Workforce Participation Rates. Available at: http://factfinder.census.gov/home/saff/main.html?_lang=en. Accessed May 28, 2004
    • (2004) Workforce Participation Rates
  • 37
    • 0034046985 scopus 로고    scopus 로고
    • Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures
    • Oleksik A, Lips P, Dawson A et al (2000) Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 15(7):1384-1392
    • (2000) J Bone Miner Res , vol.15 , Issue.7 , pp. 1384-1392
    • Oleksik, A.1    Lips, P.2    Dawson, A.3
  • 38
    • 0032524460 scopus 로고    scopus 로고
    • The association of radiographically detected vertebral fractures with back pain and function: A prospective study
    • Nevitt MC, Ettinger B, Black DM et al (1998) The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 128(10):793-800
    • (1998) Ann Intern Med , vol.128 , Issue.10 , pp. 793-800
    • Nevitt, M.C.1    Ettinger, B.2    Black, D.M.3
  • 39
    • 0029800194 scopus 로고    scopus 로고
    • Vertebral fracture and other predictors of physical impairment and health care utilization
    • Huang C, Ross PD, Wasnich RD (1996) Vertebral fracture and other predictors of physical impairment and health care utilization. Arch Intern Med 156(21):2469-2475
    • (1996) Arch Intern Med , vol.156 , Issue.21 , pp. 2469-2475
    • Huang, C.1    Ross, P.D.2    Wasnich, R.D.3
  • 40
    • 0035698323 scopus 로고    scopus 로고
    • Impact of hip and vertebral fractures on quality-adjusted life years
    • Tosteson AN, Gabriel SE, Grove MR et al (2001) Impact of hip and vertebral fractures on quality-adjusted life years. Osteoporos Int 12(12):1042-1049
    • (2001) Osteoporos Int , vol.12 , Issue.12 , pp. 1042-1049
    • Tosteson, A.N.1    Gabriel, S.E.2    Grove, M.R.3
  • 42
    • 29044436585 scopus 로고    scopus 로고
    • Potential cost-effective use of spine radiographs to detect vertebral deformity and select osteopenic post-menopausal women for amino-bisphosphonate therapy
    • Schousboe JT, Ensrud KE, Nyman JA et al (2005) Potential cost-effective use of spine radiographs to detect vertebral deformity and select osteopenic post-menopausal women for amino-bisphosphonate therapy. Osteoporos Int 16(12):1883-1893
    • (2005) Osteoporos Int , vol.16 , Issue.12 , pp. 1883-1893
    • Schousboe, J.T.1    Ensrud, K.E.2    Nyman, J.A.3
  • 43
    • 0035664686 scopus 로고    scopus 로고
    • Six and twelve month changes in bone turnover are related to reduction in vertebral fracture risk during 3 years of raloxifene treatment in postmenopausal osteoporosis
    • Bjarnason NH, Sarkar S, Duong T et al (2001) Six and twelve month changes in bone turnover are related to reduction in vertebral fracture risk during 3 years of raloxifene treatment in postmenopausal osteoporosis. Osteoporos Int 12(11):922-930
    • (2001) Osteoporos Int , vol.12 , Issue.11 , pp. 922-930
    • Bjarnason, N.H.1    Sarkar, S.2    Duong, T.3
  • 44
    • 0141625900 scopus 로고    scopus 로고
    • Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate
    • Eastell R, Barton I, Hannon RA et al (2003) Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate. J Bone Miner Res 18(6):1051-1056
    • (2003) J Bone Miner Res , vol.18 , Issue.6 , pp. 1051-1056
    • Eastell, R.1    Barton, I.2    Hannon, R.A.3
  • 45
    • 0031989253 scopus 로고    scopus 로고
    • Some reflections on cost-effectiveness analysis
    • Johannesson M, Meltzer D (1998) Some reflections on cost-effectiveness analysis. Health Economics 7:1-7
    • (1998) Health Economics , vol.7 , pp. 1-7
    • Johannesson, M.1    Meltzer, D.2
  • 46
    • 0041807885 scopus 로고    scopus 로고
    • What is the price of life and why doesn't it increase at the rate of inflation?
    • Ubel PA, Hirth RA, Chernew ME et al (2003) What is the price of life and why doesn't it increase at the rate of inflation? Arch Intern Med 163(14):1637-1641
    • (2003) Arch Intern Med , vol.163 , Issue.14 , pp. 1637-1641
    • Ubel, P.A.1    Hirth, R.A.2    Chernew, M.E.3
  • 47
    • 0037317254 scopus 로고    scopus 로고
    • Measuring population health: A comparison of three generic health status measures
    • Macran S, Weatherly H, Kind P (2003) Measuring population health: a comparison of three generic health status measures. Med Care 41(2):218-231
    • (2003) Med Care , vol.41 , Issue.2 , pp. 218-231
    • Macran, S.1    Weatherly, H.2    Kind, P.3


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