Cytokine Production from Peripheral Blood Mononuclear Cells in Patients with Ankylosing Spondylitis and Their First-Degree Relatives

Archives of Medical Research

Volumn 38, Issue 2, 2007, Pages 190-195

  Chou, Chung Tei ^a   Huo, An Ping ^b   Chang, Hsiao Ning ^a   Tsai, Chang Youh ^a   Chen, Wei Sheng ^a   Wang, Hon Pin ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Ankylosing spondylitis; Cytokines; Disease activity; First degree relatives; Tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; PHYTOHEMAGGLUTININ; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; BATH ANKYLOSING SPONDYLITIS DISEASE ACTIVITY INDEX; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; RELATIVE; SUPERNATANT;

ADOLESCENT; ADULT; CYTOKINES; FAMILY HEALTH; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; SEVERITY OF ILLNESS INDEX; SPONDYLITIS, ANKYLOSING;

EID: 33846120589     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2006.09.008     Document Type: Article

References (42)

1. Khan M.A., and van der Linden S.M. Ankylosing spondylitis and other spondyloarthropathies. Rheumatol Clin North Am 16 (1990) 551-579
2. Khan M.A. Prevalence of HLA-B27 in world population. In: López-Larrea C. (Ed). HLA-B27 in the Development of Spondyloarthropathies (1997), R.G. Landes Company, Austin, TX 95-112
3. Gonzalez-Roces S., Alvarez M.V., Gonzalez S., Dieye A., Makni H., Woodfield D.G., et al. HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis. Tissue Antigens 49 (1997) 116-112
4. Chou C.T., Pai L., Chang D.M., Lee C.F., Liang M.H., and Schumacher H.R. Prevalence of rheumatic disease in Taiwan: a population-based study of urban, suburban, and rural differences. J Rheumatol 21 (1994) 302-306
5. Beasley R.P., and Bennett P.H. Low prevalence of rheumatoid arthritis in Chinese. J Rheumatol 10 suppl (1983) 11-15
6. van der Linden S.M., Valkenburg H., and Cats A. The risk of developing ankylosing spondylitis in HLA-B27 positive individuals: a family and population study. Br J Rheumatol 22 suppl 2 (1983) 18-19
7. Moller P., Vinje O., Dale K., Berg K., and Kass E. Family studies in Bechterew's syndrome (ankylosing spondylitis). Scand J Rheumatol 13 (1984) 1-10
8. LeClercq S.A., Chaput L., and Russell A.S. Ankylosing spondylitis: a family study. J Rheumatol 10 (1983) 629-632
9. Brown M.A., Kennedy L.G., MacGregor A.J., Darke C., Duncan E., Shatford J.L., et al. Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA and the environment. Arthritis Rheum 40 (1997) 1823-1828
10. Sieper J., and Braun J. Pathogenesis of spondylarthropathies: persistent bacterial antigen, autoimmunity, or both?. Arthritis Rheum 38 (1995) 1547-1554
11. Chou C.T., Uksila J., and Toivanen P. Enterobacterial antibodies in Chinese patients with rheumatoid arthritis and ankylosing spondylitis. Clin Exp Rheumatol 16 (1998) 161-164
12. Lopez-Larrea C., Gonzalez S., and Martinez-Borra J. The role of HLA-B27 polymorphism and molecular mimicry in spondylarthropathy. Mol Med Today (1998) 540-549
13. Schirmer M., Golddberger C., Wurzner R., Duftner C., Pfeiffer K.P., Clausen J., et al. Circulating cytotoxic CD8+ CD28- T cells in ankylosing spondylitis. Arthritis Res 3 (2002) 71-76
14. Brennan F.M., Maini R.N., and Feldmann M. Role of proinflammatory cytokines in rheumatoid arthritis. Springer Semin Immunopathol 20 (1998) 133-147
15. Braun J., Yin Z., Spiller I., Siegert S., Rudwaleit M., Liu L., et al. Low secretion of tumor necrosis factor α, but no other Th1 or Th2 cytokines, by peripheral blood mononuclear cells correlates with chronicity in reactive arthritis. Arthritis Rheum 42 (1999) 2039-2044
16. Siegert S., Yin A., Radbruch A., Sieper J., and Braun J. Evidence for a different cytokine secretion pattern of peripheral blood mononuclear cells of HLA B27+ patients with ankylosing spondylitis and HLA B27+ healthy controls compared to HLA B27- negative controls. Arthritis Rheum 41 suppl 9 (1998) S287
17. Gratacos J., Collado A., Fiella X., Sanmarti R., Canete J., Llena J., et al. Serum cytokines (IL-6, TNF alpha, IL-1 beta, IFN-gamma) in ankylosing spondylitis: a close correlation between serum IL-6 and disease activity and severity. Br J Rheumatol 33 (1994) 927-931
18. Vazquez-Del M.M., Garcia-Gonzalez A., Munoz-Valle J.F., Garcia-Iglesias T., Martinez-Bonilla G., Bernard-Medina G., et al. Interleukin 1β (IL-1β). IL-10, tumor necrosis factor-α, and cellular proliferation index in peripheral blood mononuclear cells in patients with ankylosing spondylitis. J Rheumatol 29 (2002) 522-526
19. Sonel B., Tutkak H., and Duzgun N. Serum levels of IL-1 beta, TNF-alpha, IL-8, and acute phase proteins in seronegative spondyloarthropathies. Joint Bone Spine 69 (2002) 463-467
20. Claudepierre P., Rymer J.C., and Chevalier X. IL-10 plasma levels correlate with disease activity in spondyloarthropathy. J Rheumatol 24 (1997) 1659-1661
21. Keller C., Webb A., and Davis J. Cytokines in the seronegative spondyloarthropathies and their modification by TNF blockade: a brief report and literature review. Ann Rheum Dis 62 (2003) 1128-1132
22. Rudwaleit M., Siegert S., Yin Z., Eick J., Thiel A., Radbruch A., et al. Low T cell production of TNF-α and IFN-γ in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism. Ann Rheum Dis 60 (2001) 36-42
23. Gu J., Marker-Hermann E., Baeten D., Tsai W.C., Gladman D., Xiong M., et al. A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients. Rheumatology (Oxford) 41 (2002) 759-766
24. Brandt J., Haibel H., Cornely D., Sieper J., and Braun J. Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody Infliximab. Arthritis Rheum 43 (2000) 1346-1352
25. Gorman J.D., Sack K.E., and Davis J.C. Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α. N Engl J Med 346 (2002) 1349-1356
26. Canete J.D., Martinez S.E., Farres J., Sanmarti R., Blay M., Gomez A., et al. Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon γ is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies. Ann Rheum Dis 59 (2000) 263-268
27. Huizinga T.W.J., Keijsers V., Yanni G., Hall M., Ramage W., Lanchbury L., et al. Are differences in interleukin 10 production associated with joint damage?. Rheumatology 39 (2000) 1180-1188
28. Grondal G., Kristjansdottir H., Gunnlaugsdottir B., Arnason A., Lundberg I., Klareskog L., et al. Increased number of interleukin-10-producing cells in systemic lupus erythematosus patients and their first-degree relatives and spouses in Icelandic multicase families. Arthritis Rheum 42 (1999) 1649-1654
29. van der Linden S.M., Valkenburg H.A., and Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 27 (1984) 361-368
30. Garretts, Jenkinson T., Kennedy L.G., Whitelock H., Gaisford P., and Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 21 (1994) 2286-2291
31. Ebringer R.W., Cawdell D.R., Cowling P., and Ebringer A. Sequential studies in ankylosing spondylitis. Association of Klebsiella pneumoniae with active disease. Ann Rheum Dis 37 (1978) 146-151
32. De Vos M., Cuvelier C., Mielants H., Veys E., Barbier F., and Elewaut A. Ileocolonoscopy in seronegative spondylarthropathy. Gastroenterology 96 (1989) 339-344
33. Maki-Ikola O., Lehtinen K., Granfors K., Vainionpaa R., and Toivanen P. Bacterial antibodies in ankylosing spondylitis. Clin Exp Immunol 84 (1991) 42-45
34. Wuorela M., and Granfors K. Infectious agents as triggers of reactive arthritis. Am J Med Sci 316 (1998) 264-270
35. Virtala M., Kirveskari J., and Granfors K. HLA-B27 modulates the survival of Salmonella enteritidis in transfected L cells, possibly by impaired nitric oxide production. Infect Immun 65 (1997) 4236-4242
36. Laitio P., Virtala M., Salmi M., Pelliniemi L.J., Yu D.T.Y., and Granfors K. HLA-B27 modulates intracellular survival of Salmonella enteritidis on human monocytic cells. Eur J Immunol 27 (1997) 1331-1338
37. Braun J., Bollow M., Neure L., Seipelt E., Seyrekbasan F., Herbst H., et al. Use of immunohistologic and in-situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum 38 (1995) 499-505
38. Verjans G.M., Brinkman B.M.N., van Doornik C.E.M., Kijlstra A., and Verweij C.L. Polymorphism of tumor necrosis factor-alpha at position -308 in relation to ankylosing spondylitis. Clin Exp Immunol 97 (1994) 45-47
39. Fraile A., Nieto A., Beran Y., Vinasco J., Mataran L., and Martin J. Tumor necrosis factor gene polymorphisms in ankylosing spondylitis. Tissue Antigens 51 (1998) 386-390
40. Kaijzel E.L., Brinkman B.M., van Krugten M.V., Smith L., Huizinga T.W., Verjans G.M., et al. Polymorphism within the tumor necrosis factor alpha promoter region in patients with ankylosing spondylitis. J Rheumatol 26 (1999) 1110-1116
41. McGarry F., Walker R., Sturrock R., and Field M. The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27. Hum Immunol 60 (1999) 140-144
42. Gonzalez S., Torre-Alonso J.C., Martinez-Borra J., Sanchez J.A.F., Lopez-Vazquez A., Perez A.R., et al. TNF-238A promoter polymorphism contributes to susceptibility to ankylosing spondylitis in HLA-B27 negative patients. J Rheumatol 28 (2001) 1288-1293