Practical stereoselective synthesis of an α-trifluoromethyl-α- alkyl epoxide via a diastereoselective trifluoromethylation reaction

Journal of Organic Chemistry

Volumn 72, Issue 1, 2007, Pages 292-294

  Song, Jinhua J ^a   Tan, Zhulin ^a   Xu, Jinghua ^a   Reeves, Jonathan T ^a   Yee, Nathan K ^a   Ramdas, Ranjit ^a   Gallou, Fabrice ^a   Kuzmich, Katie ^a   DeLattre, Lisa ^a   Lee, Heewon ^a   Feng, Xuwu ^a   Senanayake, Chris H ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIASTEREOMERS; DIASTEREOSELECTIVITY; TRIFLUOROMETHYLATION REACTION;

ALCOHOLS; CRYSTALLIZATION; REACTION KINETICS; SYNTHESIS (CHEMICAL);

EPOXY RESINS;

5 FLUORO 2 METHOXY GAMMA,GAMMA DIMETHYL ALPHA (TRIFLUOROMETHYL) ALPHA [(TRIMETHYLSILYL)OXY] BENZENEBUTANOIC ACID; EPOXIDE; ESTER; KETONE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; DIASTEREOISOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

ALKYLATION; EPOXY COMPOUNDS; ESTERS; FLUORINE; METHYLATION; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 33846113396     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo061839l     Document Type: Article

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