Selection, purification, characterisation, and cloning of a novel heat-stable stereo-specific amidase from Klebsiella oxytoca, and its application in the synthesis of enantiomerically pure (R)- and (S)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acids and (S)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamide

Organic Process Research and Development

Volumn 6, Issue 4, 2002, Pages 497-504

  Shaw, Nicholas M ^a   Brieden, Walter ^a   De Riedmatten, Patricia ^a   Roduit, Jean Paul ^a   Zimmermann, Bertin ^a   Neumüller, Roman ^a   Naughton, Andrew ^a   Robins, Karen ^a   Tinschert, Andreas ^a   Schmid, Evelyne ^a   Hischier, Marie Louise ^a   Venetz, Veronika ^a   Werlen, Josef ^a   Zimmermann, Thomas ^a  

^a LONZA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3,3,3 TRIFLUORO 2 HYDROXY 2 METHYLPROPIONAMIDE; 3,3,3 TRIFLUORO 2 HYDROXY 2 METHYLPROPIONIC ACID; ACETOACETIC ACID DERIVATIVE; AMIDASE; AMIDE; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; DRUG SYNTHESIS; ENANTIOMER; ENZYME ANALYSIS; ENZYME PURIFICATION; HYDROLYSIS; KLEBSIELLA OXYTOCUM; NONHUMAN;

EID: 0036328455     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op020025d     Document Type: Article

References (18)