Optimal purification method for Herpes-based viral vectors that confers minimal cytotoxicity for systemic route of vector administration

Journal of Virological Methods

Volumn 139, Issue 2, 2007, Pages 166-174

  Sia, Kian Chuan ^a   Wang, Grace Y ^a   Ho, Ivy A W ^a   Khor, Hong Yuan ^a   Miao, Lv ^a   Hui, Kam M ^a   Lam, Paula Y P ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

Helper virus; HSV 1 amplicon viral vector; In vivo toxicity; Purification; Sucrose gradient; Systemic administration

Indexed keywords

HERPESVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENE TRANSFER; HELPER VIRUS; HERPES SIMPLEX VIRUS 1; IN VIVO STUDY; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUCROSE GRADIENT; VIRUS ENVELOPE; VIRUS RECOMBINANT;

ANIMALS; CERCOPITHECUS AETHIOPS; GENE TRANSFER TECHNIQUES; GENES, VIRAL; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; MICE; MICE, INBRED BALB C; VERO CELLS;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 33846091056     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2006.09.023     Document Type: Article

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