S-(+)-fenfluramine-induced nociceptive behavior in mice: Involvement of interactions between spinal serotonin and substance P systems

Neuropeptides

Volumn 41, Issue 1, 2007, Pages 33-38

  Tan No, Koichi ^a   Takahashi, Katsuaki ^a   Shimoda, Masakazu ^a   Sugawara, Mai ^a   Nakagawasai, Osamu ^a   Niijima, Fukie ^a   Sato, Takumi ^b   Satoh, Susumu ^b   Tadano, Takeshi ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Intrathecal administration; Mouse; Nociceptive behavior; S (+) fenfluramine; Serotonin; Substance P

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; ANTISERUM; FENFLURAMINE; KETANSERIN TARTRATE; MORPHINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; RAMOSETRON; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN 3 ANTAGONIST; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; LICKING; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SCRATCHING; SEROTONIN RELEASE;

ANIMALS; FENFLURAMINE; MALE; MICE; MORPHINE; PAIN; SEROTONIN; SEROTONIN AGENTS; SPINAL CORD; SUBSTANCE P;

EID: 33846071623     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.npep.2006.10.003     Document Type: Article

References (28)

1. Araneda R., and Andrade R. 5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediated opposing responses on membrane excitability in rat association cortex. Neuroscience 40 (1991) 399-412
2. Barnes N.M., and Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 38 (1999) 1083-1152
3. Bertelsen A.K., Afrah A.W., Gustafsson H., Tjølsen A., Hole K., and Stiller C.-O. Stimulation of spinal 5-HT2A/2C receptors potentiates the capsaicin-induced in vivo release of substance P-like immunoreactivity in the rat dorsal horn. Brain Research 987 (2003) 10-16
4. Brandao M.L., Lopez-Garcia J.A., Graeff F.G., and Roberts M.H.T. Electrophysiological evidence for excitatory 5-HT2 and depressant 5-HT1A receptors on neurons of the rat midbrain tectum. Brain Research 556 (1991) 259-266
5. De Vivo M., and Maayani S. Characterization of the 5-hydroxytryptamine1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. Journal of Pharmacology and Experimental Therapeutics 238 (1986) 248-253
6. Eide P.K., and Hole K. Interactions between serotonin and substance P in the spinal regulation of nociception. Brain Research 550 (1991) 225-230
7. Eide P.K., and Hole K. Different role of 5-HT1A and 5-HT2 receptors in spinal cord in the control of nociceptive responsiveness. Neuropharmacology 30 (1991) 727-731
8. Eide P.K., and Hole K. The role of 5-hydroxytryptamine (5-HT) receptor subtypes and plasticity in the 5-HT systems in the regulation of nociceptive sensitivity. Cephalalgia 13 (1993) 75-85
9. El-Yassir N., Fleetwood-Walker S.M., and Mitchell R. Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes. Brain Research 456 (1988) 147-158
10. Fields H.L., Heinricher M.M., and Mason P. Neurotransmitters in nociceptive modulatory circuits. Annual Review of Neuroscience 14 (1991) 219-245
11. Fozard J.R. 5-HT: the enigma variations. Trends in Pharmacological Sciences 8 (1987) 501-506
12. Furst S. Transmitters involved in antinociception in the spinal cord. Brain Research Bulletin 48 (1999) 129-141
13. Hoyer D., Clarke D.E., Fozard J.R., Harting P.R., Martin G.R., Mylecharane E.J., Saxena P.R., and Humphrey P.P. International union of pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacological Review 46 (1994) 157-203
14. Hylden J.L.K., and Wilcox G.L. Intrathecal morphine in mice, a new technique. European Journal Pharmacology 67 (1980) 313-316
15. Johansson O., Hökfelt T., Pernow B., Jeffcoate S.L., White N., Steinbusch H.W.M., Verhofstad A.A.J., Emson P.C., and Spindel E. Immunohistochemical support for three putative transmitters in one neuron: coexistence of 5-hydroxytryptamine, substance P- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord. Neuroscience 6 (1981) 1857-1881
16. Mjellem N., Lund A., and Hole K. Different functions of spinal 5-HT1A and 5-HT2 receptor subtypes in modulating behaviour induced by excitatory amino acid receptor agonists in mice. Brain Research 626 (1993) 78-82
17. Sakurada T., Yamada T., Tan-No K., Manome Y., Sakurada S., Kisara K., and Ohba M. Differential effects of substance P analogs on neurokinin 1 receptor agonists in the mouse spinal cord. Journal of Pharmacology and Experimental Therapeutics 259 (1991) 205-210
18. Sakurada T., Manome Y., Tan-No K., Matsunaga Y., Sakurada S., and Kisara K. Possible involvement of the spinal substance P system in pilocarpine-induced scratching in mice. Pharmacology Biochemistry and Behavior 44 (1993) 439-445
19. Sakurada T., Wako K., Sakurada C., Manome Y., Tan-No K., Sakurada S., and Kisara K. Spinally-mediated behavioural responses evoked by intrathecal high-dose morphine: possible involvement of substance P in the mouse spinal cord. Brain Research 724 (1996) 213-221
20. Sakurada T., Sakurada C., Tan-No K., and Kisara K. Neurokinin receptor antagonists. Therapeutic potential in the treatment of pain syndromes. CNS Drugs 8 (1997) 436-447
21. Sakurada T., Katsuyama S., Sakurada S., Inoue M., Tan-No K., Kisara K., Sakurada C., Ueda H., and Sasaki J. Nociceptin-induced scratching, biting and licking in mice: involvement of spinal NK1 receptors. British Journal of Pharmacology 127 (1999) 1712-1718
22. Takahashi K., Sakurada T., Sakurada S., Kuwahara H., Yonezawa A., Ando R., and Kisara K. Behavioural characterization of substance P-induced nociceptive response in mice. Neuropharmacology 26 (1987) 1289-1293
23. Tan-No K., Taira A., Sakurada T., Inoue M., Sakurada S., Tadano T., Sato T., Sakurada C., Nylander I., Silberring J., Terenius L., and Kisara K. Inhibition of dynorphin-converting enzymes prolongs the antinociceptive effect of intrathecally administered dynorphin in the mouse formalin test. European Journal of Pharmacology 314 (1996) 61-67
24. Tan-No K., Taira A., Wako K., Niijima F., Nakagawasai O., Tadano T., Sakurada C., Sakurada T., and Kisara K. Intrathecally administered spermine produces the scratching, biting and licking behavior in mice. Pain 86 (2000) 55-61
25. Tan-No K., Esashi A., Nakagawasai O., Niijima F., Tadano T., Sakurada C., Sakurada T., Bakalkin G., Terenius L., and Kisara K. Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-d-aspartate receptor mechanism. Brain Research 952 (2002) 7-14
26. Tan-No K., Esashi A., Taira A., Nakagawasai O., Niijima F., Sakurada C., Sakurada T., and Tadano T. Intrathecal spermine and spermidine at high-doses induce antinociceptive effects in the mouse capsaicin test. Biogenic Amines 17 (2003) 313-320
27. Tan-No K., Takahashi H., Nakagawasai O., Niijima F., Sato T., Satoh S., Sakurada S., Marinova Z., Yakovleva T., Bakalkin G., Terenius L., and Tadano T. Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation. Pain 113 (2005) 301-309
28. Tan-No K., Taira A., Nakagawasai O., Niijima F., Demuth H.-U., Silberring J., Terenius L., and Tadano T. Differential effects of N-peptidyl-O-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test. Neuropeptides 39 (2005) 569-573