Chemically programmed antibodies: Endothelin receptor targeting CovX-Bodies™

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 2, 2007, Pages 501-506

  Doppalapudi, Venkata R ^a   Tryder, Nancy ^a   Li, Lingna ^a   Aja, Teresa ^a   Griffith, David ^a   Liao, Francesca Fang ^a   Roxas, Giovanni ^a   Ramprasad, Mysore P ^a   Bradshaw, Curt ^a   Barbas III, Carlos F ^a  

^a CovX Research LLC ^*  (United States)

Author keywords

Aldolase antibody; Antitumor efficacy; CovX Body ; Endothelin A; Endothelin A (ETA) antagonists; Monoclonal antibodies

Indexed keywords

ANTIBODY; BIVALENT ANTIBODY; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; LYSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PROSTATE CANCER; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES; ANTINEOPLASTIC AGENTS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; INDICATORS AND REAGENTS; MICE; MICE, NUDE; MOLECULAR CONFORMATION; NEOPLASM TRANSPLANTATION; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846061734     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.10.009     Document Type: Article

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