Impact of Lotensin and Salviae on the Changes of TGF-Beta1 and Its Receptors in a Rat Model of Chronic Cyclosporine-Induced Nephropathy

Transplantation Proceedings

Volumn 38, Issue 7, 2006, Pages 2183-2186

  Peng, B ^a   Li, M ^a   Niu, T ^a   He, S ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENAZEPRIL; CHINESE DRUG; CRYPTOTANSHINONE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MESSENGER RNA; SALVIA MILTIORRHIZA EXTRACT; TANSHINONE; TANSHINONE I; TANSHINONE II; TANSHINONE VI; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; GENE EXPRESSION REGULATION; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RECEPTOR DOWN REGULATION; RNA ANALYSIS; SALVIA MILTIORRHIZA; SODIUM DEPLETION; SODIUM RESTRICTION;

ACTIVIN RECEPTORS, TYPE I; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BENZAZEPINES; CYCLOSPORINE; KIDNEY; MODELS, ANIMAL; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SALVIA; TISSUE EXTRACTS; TRANSFORMING GROWTH FACTOR BETA;

EID: 33846054928     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.07.019     Document Type: Article

References (15)

1. Qiao B.P., Tang X.D., and Ruan Q. Experimental study of compound Salvia injection in preventing and treating chronic nephrotoxicity induced by cyclosporin A in rats. Zhongguo Zhong Xi Yi Jie He Za Zhi 21 (2001) 611
2. Burdmann E.A., Andoh T.F., Nast C.C., et al. Prevention of experimental cyclosporin-induced interstitial fibrosis by losartan and enalapril. Am J Physiol 269 (1995) F491
3. Kaneto H., Morrissey J., Mccracken R., et al. Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int 45 (1994) 1637
4. Shihab F.S., Andoh T.F., Tanner A.M., et al. Role of transforming growth factor-beta1 in experimental chronic cyclosporine nephropathy. Kidney Int 49 (1996) 1141
5. Hong S.W., Isomo M., Chen S., et al. Increased glomerular and tubular expression of transforming growth factor-beta1, its type 2 receptor, and activation of the Smad signaling pathway in the db/db mouse. Am J Pathol 158 (2001) 1653
6. Mason J., Muller-Schweinitzer E., Dupont M., et al. Cyclosporine and the renin-angiotensin system. Kidney Int 32 Suppl (1991) S28
7. Julien J., Farge D., Kreft-Jais C., et al. Cyclosporine-induced stimulation of the renin-angiotensin system after liver and heart transplantation. Transplantation 56 (1993) 885
8. Gardiner D.S., Watson M.A., Junor B.R., et al. The effect of conversion from cyclosporin to azathioprine on renin-containing cells in renal allograft biopsies. Nephrol Dial Transplant 6 (1991) 363
9. Qiao B.P., Tang X.D., Li D.M., et al. Effect of cyclosporine A on transforming growth factor-betal and rennin mRNA in a rat model of cyclosporine-induced chronic nephropathy. Transplant J China 22 (2001) 274
10. Kagami S., Border W.A., Miller D.E., et al. Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 93 (1994) 2431
11. Young B.A., Burdmann E.A., Johnson R.J., et al. Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity. Kidney Int 48 (1995) 439
12. Lee S.K., Park J.Y., Yu E.S., et al. Individual or combined effects of enalapril and verapamil on chronic cyclosporine nephrotoxicity in rats. J Korean Med Sci 14 (1999) 653
13. Rosen S., Greenfeld Z., and Mayer B. Chronic cyclosporine-induced nephropathy in the rat. A medullary ray and inner stripe injury. Transplantation 49 (1990) 445
14. Shihab F.S., Bennett W.M., Tanner A.M., et al. Angiotensin II blockade decreases TGF-beta1 and matrix proteins in cyclosporine nephropathy. Kidney Int 52 (1997) 660
15. Xiao S.G., Zhao M.T., and Zhang Y.H. Effect of Salviae on cyclosporine-induced chronic nephropathy in a rat model. Transplant J China 14 (1993) 71