Interaction of omeprazole with a methylated derivative of β-cyclodextrin: Phase solubility, NMR spectroscopy and molecular simulation

Pharmaceutical Research

Volumn 24, Issue 2, 2007, Pages 377-389

  Figueiras, Ana ^a   Sarraguca J M G ^b   Carvalho, Rui A ^c   Pais, A A C C ^b   Veiga, Francisco J B ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Cyclodextrin; Inclusion complex; Molecular dynamics; NMR spectroscopy; Omeprazole; Phase solubility studies

Indexed keywords

BENZIMIDAZOLE; BETA CYCLODEXTRIN; EXCIPIENT; METHYL BETA CYCLODEXTRIN; OMEPRAZOLE;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; METHYLATION; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SIMULATION; STOICHIOMETRY; VARIANCE;

BETA-CYCLODEXTRINS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OMEPRAZOLE; SOLUBILITY; SOLUTIONS;

EID: 33846047876     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9161-8     Document Type: Article

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