Interaction between DNA gyrase and quinolones: Effects of alanine mutations at GyrA subunit residues Ser83 and Asp87

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 7, 2001, Pages 1994-2000

  Barnard, F M ^a   Maxwell, A ^a  

^a JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); ENOXACIN; NORFLOXACIN; OFLOXACIN; QUINOLONE DERIVATIVE;

ARTICLE; DNA DEGRADATION; DNA SUPERCOILING; DRUG PROTEIN BINDING; ESCHERICHIA COLI; GRAM NEGATIVE INFECTION; NONHUMAN; PRIORITY JOURNAL;

4-QUINOLONES; ALANINE; AMINO ACID SUBSTITUTION; ANTI-INFECTIVE AGENTS; ASPARTIC ACID; BINDING, COMPETITIVE; CALCIUM; DNA TOPOISOMERASES, TYPE II; DNA, BACTERIAL; DNA, SUPERHELICAL; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; HUMANS; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; SERINE;

EID: 0034959675     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.7.1994-2000.2001     Document Type: Article

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