-
2
-
-
0024358652
-
Brain monoamine oxidase (MAO) B: A unique neurotoxin- and neurotransmitter-producing enzyme
-
Youdim MBH. Brain monoamine oxidase (MAO) B: a unique neurotoxin- and neurotransmitter-producing enzyme. Prog. Neuropsychopharmacol. Biol. Psychiatry 1989; 13: 363.
-
(1989)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.13
, pp. 363
-
-
Youdim, M.B.H.1
-
3
-
-
0021276089
-
Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
-
Chiba K, Trevor AJ, Castagnoli N Jr. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem. Biophys. Res. Commun. 1984; 120: 574.
-
(1984)
Biochem. Biophys. Res. Commun
, vol.120
, pp. 574
-
-
Chiba, K.1
Trevor, A.J.2
Castagnoli Jr., N.3
-
4
-
-
0025134990
-
-
Ottoboni S, Carlson TJ, Trager WF, Castagnoli K, Castagnoli N Jr. Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chem. Res. Toxicol. 1990; 3: 423.
-
Ottoboni S, Carlson TJ, Trager WF, Castagnoli K, Castagnoli N Jr. Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chem. Res. Toxicol. 1990; 3: 423.
-
-
-
-
5
-
-
0018697618
-
Cyclopropylamines as suicide substrates for cytochromes P-450
-
Hanzlik RP, Kishore V, Tullman R. Cyclopropylamines as suicide substrates for cytochromes P-450. J. Med. Chem. 1979; 22: 759.
-
(1979)
J. Med. Chem
, vol.22
, pp. 759
-
-
Hanzlik, R.P.1
Kishore, V.2
Tullman, R.3
-
6
-
-
0022376527
-
Revised mechanism for inactivation of mitochondrial monoamine oxidase by N-cyclopropylbenzylamine
-
Vazquez ML, Silverman RG. Revised mechanism for inactivation of mitochondrial monoamine oxidase by N-cyclopropylbenzylamine. Biochemistry 1985; 24: 6538.
-
(1985)
Biochemistry
, vol.24
, pp. 6538
-
-
Vazquez, M.L.1
Silverman, R.G.2
-
7
-
-
15244352849
-
-
13C NMR. Bioorg. Med. Chem. 2005; 13: 2975.
-
13C NMR. Bioorg. Med. Chem. 2005; 13: 2975.
-
-
-
-
8
-
-
0037028810
-
Microsomal P450-catalyzed N-dealkylation of N,N-dialkylanilines: Evidence for a C(alpha)-H abstraction mechanism
-
Bhakta MN, Wimalasena K. Microsomal P450-catalyzed N-dealkylation of N,N-dialkylanilines: evidence for a C(alpha)-H abstraction mechanism. J. Am. Chem. Soc. 2002; 214: 1844.
-
(2002)
J. Am. Chem. Soc
, vol.214
, pp. 1844
-
-
Bhakta, M.N.1
Wimalasena, K.2
-
9
-
-
0037125528
-
-
Shaffer CL, Harriman S, Koen YM, Hanzlik RP. Formation of Cyclopropanone during Cytochrome P450-catalyzed N-Dealkylation of a Cyclopropylamine. J. Am. Chem. Soc. 2002; 124: 8268.
-
Shaffer CL, Harriman S, Koen YM, Hanzlik RP. Formation of Cyclopropanone during Cytochrome P450-catalyzed N-Dealkylation of a Cyclopropylamine. J. Am. Chem. Soc. 2002; 124: 8268.
-
-
-
-
10
-
-
24644510168
-
Model electrochemical-mass spectrometric studies of the cytochrome P450-catalyzed oxidations of cyclic tertiary allylamines
-
Jurva U, Bissel P, Isin EM, Igarashi K, Kuttab S, Castagnoli N Jr. Model electrochemical-mass spectrometric studies of the cytochrome P450-catalyzed oxidations of cyclic tertiary allylamines. J. Am. Chem. Soc. 2005; 127: 12368.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 12368
-
-
Jurva, U.1
Bissel, P.2
Isin, E.M.3
Igarashi, K.4
Kuttab, S.5
Castagnoli Jr., N.6
-
11
-
-
0029740928
-
-
Nimkar SK, Anderson A, Rimoldi JM, Stanton M, Castagnoli KP Jr, Mabic S, Wang Y-X, Castagnoli N. Synthesis and monoamine oxidase-B catalyzed oxidation of C-4 heteroaromatic substituted 1,2,3,6-tetrahydropyridine derivatives. Chem. Res. Toxicol. 1996; 9: 1013.
-
Nimkar SK, Anderson A, Rimoldi JM, Stanton M, Castagnoli KP Jr, Mabic S, Wang Y-X, Castagnoli N. Synthesis and monoamine oxidase-B catalyzed oxidation of C-4 heteroaromatic substituted 1,2,3,6-tetrahydropyridine derivatives. Chem. Res. Toxicol. 1996; 9: 1013.
-
-
-
-
12
-
-
0034939971
-
-
Kuttab S, Shang J, Castagnoli N Jr. Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine. Bioorg. Med. Chem. 2001; 9: 1685.
-
Kuttab S, Shang J, Castagnoli N Jr. Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine. Bioorg. Med. Chem. 2001; 9: 1685.
-
-
-
-
13
-
-
0002600682
-
-
Markey SP, Castagnoli N Jr, Trevor AJ, Kopin IJ eds, Academic Press: New York
-
Pitts SM, Markey SP, Murphy DL, Weiss A. In Recommended Practices for the Safe Handling of MPTP, Markey SP, Castagnoli N Jr, Trevor AJ, Kopin IJ (eds). Academic Press: New York, 1995; 703.
-
(1995)
Recommended Practices for the Safe Handling of MPTP
, pp. 703
-
-
Pitts, S.M.1
Markey, S.P.2
Murphy, D.L.3
Weiss, A.4
-
14
-
-
0032425348
-
-
Zhao Z, Mabic S, Kuttab S, Franot C, Castagnoli K, Castagnoli N Jr. Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6- tetrahydropyridine. Bioorg. Med. Chem. 1998; 6: 2531.
-
Zhao Z, Mabic S, Kuttab S, Franot C, Castagnoli K, Castagnoli N Jr. Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6- tetrahydropyridine. Bioorg. Med. Chem. 1998; 6: 2531.
-
-
-
-
15
-
-
0007512358
-
Palladium-catalyzed alkylations in aqueous media
-
Casalnuovo AL, Calabrese JC. Palladium-catalyzed alkylations in aqueous media. J. Am. Chem. Soc. 1990; 112: 4324.
-
(1990)
J. Am. Chem. Soc
, vol.112
, pp. 4324
-
-
Casalnuovo, A.L.1
Calabrese, J.C.2
-
16
-
-
0036736284
-
13C labeled N-cyclopropylamine tetrahydropyridine derivative
-
13C labeled N-cyclopropylamine tetrahydropyridine derivative. J. Labelled Comp. Radiopharm. 2002; 45: 813.
-
(2002)
J. Labelled Comp. Radiopharm
, vol.45
, pp. 813
-
-
Kuttab, S.1
Mabic, S.2
-
17
-
-
0026774923
-
-
Hall L, Murry S, Castagnoli K, Castagnoli N Jr. Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators. Chem. Res. Toxicol. 1992; 5: 625.
-
Hall L, Murry S, Castagnoli K, Castagnoli N Jr. Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators. Chem. Res. Toxicol. 1992; 5: 625.
-
-
-
-
19
-
-
0037015447
-
One-Step Synthesis of 3-aryl- and 3,4-diaryl-(1H)-pyrroles using tosylmethyl isocyanide (TOSMIC)
-
Smith ND, Huang D, Cosford NDP. One-Step Synthesis of 3-aryl- and 3,4-diaryl-(1H)-pyrroles using tosylmethyl isocyanide (TOSMIC). Org. Lett. 2002; 4: 3537.
-
(2002)
Org. Lett
, vol.4
, pp. 3537
-
-
Smith, N.D.1
Huang, D.2
Cosford, N.D.P.3
-
20
-
-
0026450944
-
-
Zhao Z, Dalvie D, Naiman N, Castagnoli K, Castagnoli N Jr. Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6- tetrahydropyridine analogs of MPTP. J. Med. Chem. 1992; 35: 4473.
-
Zhao Z, Dalvie D, Naiman N, Castagnoli K, Castagnoli N Jr. Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6- tetrahydropyridine analogs of MPTP. J. Med. Chem. 1992; 35: 4473.
-
-
-
-
21
-
-
0042364092
-
Preparation of N-phenyl-1,2-dihydropyridine
-
SaundersM, Gold EH. Preparation of N-phenyl-1,2-dihydropyridine. J. Org. Chem. 1962; 27: 1439.
-
(1962)
J. Org. Chem
, vol.27
, pp. 1439
-
-
Saunders, M.1
Gold, E.H.2
-
22
-
-
84987573884
-
The unsubstituted 5-azoniafulvenyl ion has been generated from the N-pyrrolidinylmethyl precursor and trapped as C-arylated products
-
Burger U, Bringhen AO, Wirthner PJ, Schärer J-C. The unsubstituted 5-azoniafulvenyl ion has been generated from the N-pyrrolidinylmethyl precursor and trapped as C-arylated products. Helv. Chim. Acta 1985; 68: 2275.
-
(1985)
Helv. Chim. Acta
, vol.68
, pp. 2275
-
-
Burger, U.1
Bringhen, A.O.2
Wirthner, P.J.3
Schärer, J.-C.4
-
23
-
-
0008589014
-
Mass spectrometry in structural and stereochemical problems. LXIII. Hydrogen rearrangements induced by electron impact on N-n-butyl- and N-n-pentylpyrroles
-
Duffield AM, Beugelmans R, Budzikiewicz H, Lightner DA, Williams DH, Djerassi C. Mass spectrometry in structural and stereochemical problems. LXIII. Hydrogen rearrangements induced by electron impact on N-n-butyl- and N-n-pentylpyrroles. J. Am. Chem. Soc. 1965; 87: 805.
-
(1965)
J. Am. Chem. Soc
, vol.87
, pp. 805
-
-
Duffield, A.M.1
Beugelmans, R.2
Budzikiewicz, H.3
Lightner, D.A.4
Williams, D.H.5
Djerassi, C.6
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