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Volumn 124, Issue 9, 2002, Pages 1844-1845
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Microsomal P450-catalyzed N-dealkylation of N,N-dialkylanilines: Evidence for a Cα-H abstraction mechanism
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Author keywords
[No Author keywords available]
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Indexed keywords
AMINE;
ANILINE DERIVATIVE;
CYCLOPROPANE DERIVATIVE;
CYTOCHROME P450;
DEUTERIUM;
ETHER DERIVATIVE;
HEME OXYGENASE;
NITROGEN;
OXIDIZING AGENT;
PHENOBARBITAL;
PROPYLAMINE;
PYRIDINE DERIVATIVE;
TRIETHYLAMINE;
FERRIC ION;
PYRIDINE;
ARTICLE;
DEALKYLATION;
DEMETHYLATION;
ELECTRON TRANSPORT;
ENZYME SUBSTRATE;
EPOXIDATION;
GAS CHROMATOGRAPHY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYDROXYLATION;
LIVER MICROSOME;
MASS SPECTROMETRY;
MICROSOME;
NONHUMAN;
OXIDATION REDUCTION POTENTIAL;
OXYGENATION;
PROTON TRANSPORT;
SYNTHESIS;
XENOBIOTIC METABOLISM;
ALKYLATION;
ANIMAL;
BINDING SITE;
CATALYSIS;
CHEMISTRY;
ENZYMOLOGY;
KINETICS;
METABOLISM;
RAT;
ALKYLATION;
ANILINE COMPOUNDS;
ANIMALS;
BINDING SITES;
CATALYSIS;
CYTOCHROME P-450 ENZYME SYSTEM;
FERRIC COMPOUNDS;
KINETICS;
MICROSOMES, LIVER;
PYRIDINES;
RATS;
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EID: 0037028810
PISSN: 00027863
EISSN: None
Source Type: Journal
DOI: 10.1021/ja011041d Document Type: Article |
Times cited : (44)
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References (51)
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