Colocalization between β-catenin and insulin suggests a novel role for the adherens junction in β-cell function [6]

Pancreas

Volumn 34, Issue 1, 2007, Pages 170-171

  Hodgkin, Matthew N ^a   Rogers, Gareth J ^a   Squires, Paul E ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CALCIUM CHANNEL; CELL ADHESION MOLECULE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEPATOCYTE NUCLEAR FACTOR 1; INSULIN; MYOSIN; NERVE CELL ADHESION MOLECULE; PDZ PROTEIN; PROTEIN P120; RHO KINASE; UVOMORULIN;

CELL CONTACT; CELL FUNCTION; CELL JUNCTION; CELL MEMBRANE; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; INSULIN RELEASE; LETTER; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STAINING;

ADHERENS JUNCTIONS; ANIMALS; BETA CATENIN; INSULIN; INSULIN-SECRETING CELLS;

EID: 33845981512     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000240616.28098.55     Document Type: Letter

References (8)

1. D'Souza-Schorey C. Disassembling adherens junctions: breaking up is hard to do. Trends Cell Biol. 2005;15:19-26.
2. Dahl U, Sjodin A, Semb H. Cadherins regulate aggregation of pancreatic beta-cells in vivo. Development. 1996;122:2895-2902.
3. Yamagata K, Nammo T, Moriwaki M, et al. Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes. Diabetes. 2002;51:114-123.
4. Lilla V, Webb G, Rickenbach K, et al. Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinology. 2003;144:1368-1379.
5. Collares-Buzato CB, Carvalho CPF, Furtado AG, et al. Upregulation of the expression of tight and adherens junction-associated proteins during maturation of neonatal pancreatic islets in vitro. J Mol Histol. 2004;35:811-822.
6. Bamji SX, Shimazu K, Kimes N, et al. Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron. 2003;40:719-731.
7. Piccoli G, Rutishauser U, Bruses J. N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase. J Neurosci. 2004;24:10919-10923.
8. Ko KS, Arora PD, McCulloch CAG. Cadherins mediate intercellular mechanical signaling in fibroblasts by activation of stretch-sensitive calcium-permeable channels. J Biol Chem. 2001;276:35967-35977.