Investigation of the catalytic and structural roles of conserved histidines of human coproporphyrinogen oxidase using site-directed mutagenesis

Medical Science Monitor

Volumn 13, Issue 1, 2007, Pages

  Gitter, Shani J ^a   Cooper, Christopher L ^a   Friesen, Jon A ^a   Lash, Timothy D ^a   Jones, Marjorie A ^a  

^a ILLINOIS STATE UNIVERSITY   (United States)

Author keywords

Catalysis; Heme; Histidine; Mutagenesis; Porphyrin

Indexed keywords

ALANINE; COPROPORPHYRINOGEN; COPROPORPHYRINOGEN III; COPROPORPHYRINOGEN OXIDASE; HISTIDINE; MESOPORPHYRINOGEN VI; PORPHYRINOGEN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; CATALYSIS; CONSERVED SEQUENCE; COPROPORPHYRINOGEN OXIDASE; COPROPORPHYRINOGENS; ESCHERICHIA COLI; GENE EXPRESSION; HISTIDINE; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; OLIGOPEPTIDES; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33845978082     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

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