The enigma of coproporphyrinogen oxidase: How does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups?

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4506-4509

  Lash, Timothy D ^a  

^a ILLINOIS STATE UNIVERSITY   (United States)

Author keywords

Coproporphyrinogen oxidase; Heme biosynthesis; Oxidative enzymes; Porphyria; Porphyrinogens

Indexed keywords

COPROPORPHYRINOGEN OXIDASE; METAL ION; OXYGEN; PORPHYRINOGEN; VINYL DERIVATIVE;

ARTICLE; DECARBOXYLATION; DRUG MECHANISM; ENZYME MECHANISM; MOLECULE; OXIDATION;

CARBOXYLIC ACIDS; COPROPORPHYRINOGEN OXIDASE; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXYGEN; SUBSTRATE SPECIFICITY;

EID: 24344444114     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.010     Document Type: Article

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