Adoptive transfer of dying cells causes bystander-induced apoptosis

Biochemical and Biophysical Research Communications

Volumn 353, Issue 3, 2007, Pages 780-785

  Schwulst, Steven J ^a   Davis, Christopher G ^a   Coopersmith, Craig M ^a   Hotchkiss, Richard S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Bcl 2; Lymphocyte; Necrosis; Sepsis; Splenocyte

Indexed keywords

PROTECTIVE AGENT; PROTEIN BCL 2; RAG1 PROTEIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BYSTANDER EFFECT; C57BL MOUSE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; APOPTOSIS; BYSTANDER EFFECT; CELL DEATH; LYMPHOCYTE TRANSFUSION; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-BCL-2; SPLEEN;

MUS;

EID: 33845975952     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.12.098     Document Type: Article

References (22)

1. + T lymphocytes in humans. J. Immunol. 166 (2001) 6952-6963
2. Heidecke C.D., Hensler T., Weighardt H., Zantl N., Wagner H., Siewert J.R., and Holzmann B. Selective defects of T lymphocyte function in patients with lethal intraabdominal infection. Am. J. Surg. 178 (1999) 288-292
3. Wesche D.E., Lomas-Neira J.L., Perl M., Chung C.S., and Ayala A. Leukocyte apoptosis and its significance in sepsis and shock. J. Leukoc. Biol. 78 (2005) 325-337
4. Hotchkiss R.S., Chang K.C., Swanson P.E., Tinsley K.W., Hui J.J., Klender P., Xanthoudakis S., Roy S., Black C., Grimm E., Aspiotis R., Han Y., Nicholson D.W., and Karl I.E. Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat. Immunol. 1 (2000) 496-501
5. Schwulst S.J., Grayson M.H., Dipasco P.J., Davis C.G., Brahmbhatt T.S., Ferguson T.A., and Hotchkiss R.S. Agonistic monoclonal antibody against cd40 receptor decreases lymphocyte apoptosis and improves survival in sepsis. J. Immunol. 177 (2006) 557-565
6. Hotchkiss R.S., Tinsley K.W., Swanson P.E., Chang K.C., Cobb J.P., Buchman T.G., Korsmeyer S.J., and Karl I.E. Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc. Natl. Acad. Sci. USA 96 (1999) 14541-14546
7. Hotchkiss R.S., Swanson P.E., Knudson C.M., Chang K.C., Cobb J.P., Osborne D.F., Zollner K.M., Buchman T.G., Korsmeyer S.J., and Karl I.E. Over expression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J. Immunol. 162 (1999) 4148-4156
8. Iwata A., Stevenson V.M., Minard A., Tasch M., Tupper J., Lagasse E., Weissman I., Harlan J.M., and Winn R.K. Over-expression of Bcl-2 provides protection in septic mice by a trans effect. J. Immunol. 171 (2003) 3136-3141
9. Coopersmith C.M., O'Donnell D., and Gordon J.I. Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice. Am. J. Physiol. 276 (1999) G677-G686
10. Hotchkiss R.S., McConnell K.W., Bullok K., Davis C.G., Chang K.C., Schwulst S.J., Dunne J.C., Dietz G.P., Bahr M., McDunn J.E., Karl I.E., Wagner T.H., Cobb J.P., Coopersmith C.M., and Piwnica-Worms D. TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo. J. Immunol. 176 (2006) 5471-5477
11. Mothersill C., and Seymour C. Radiation-induced bystander effects: past history and future directions. Radiat. Res. 155 (2001) 759-767
12. Mothersill C., Seymour C.B., and Joiner M.C. Relationship between radiation-induced low-dose hypersensitivity and the bystander effect. Radiat. Res. 157 (2002) 526-532
13. Maguire P., Mothersill C., Seymour C., and Lyng F.M. Medium from irradiated cells induces dose-dependent mitochondrial changes and BCL2 responses in unirradiated human keratinocytes. Radiat. Res. 163 (2005) 384-390
14. Hotchkiss R.S., Chang K.C., Grayson M.H., Tinsley T.W., Dunne B.S., Davis C.G., Osborne D.F., and Karl I.E. Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis. Proc. Natl. Acad. Sci. USA 100 (2003) 6724-6729
15. Domen J., Gandy K.L., and Weissman I.L. Systemic over expression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91 (1998) 2272-2282
16. Chaudry I.H., Wichterman K.A., and Baue A.E. Effect of sepsis on tissue adenine nucleotide levels. Surgery 85 (1979) 205-211
17. Hotchkiss R.S., Osmon S.B., Chang K.C., Wagner T.H., Coopersmith C.M., and Karl I.E. Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways. J. Immunol. 174 (2005) 5110-5118
18. Hotchkiss R.S., Tinsley K.W., and Karl I.E. Role of apoptotic cell death in sepsis. Scand. J. Infect. Dis. 35 (2003) 585-592
19. Lyng F.M., Seymour C.B., and Mothersill C. Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis. Br. J. Cancer 83 (2000) 1223-1230
20. Docke W.D., Randow F., Syrbe U., Krausch D., Asadullah K., Reinke P., Volk H.D., and Kox W. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat. Med. 3 (1997) 678-681
21. Meakins J.L., Pietsch J.B., Bubenick O., Kelly R., Rode H., Gordon J., and MacLean L.D. Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma. Ann. Surg. 186 (1977) 241-250
22. Fadok V.A., Bratton D.L., Konowal A., Freed P.W., Westcott J.Y., and Henson P.M. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 101 (1998) 890-898