The heat is on: An expanding role for hypoxia-inducible factors in kidney transplantation

Journal of the American Society of Nephrology

Volumn 18, Issue 1, 2007, Pages 13-15

  Nangaku, Masaomi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA;

ALLOGRAFT; EDITORIAL; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; KIDNEY TRANSPLANTATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; TRANSCRIPTION REGULATION;

EID: 33845974128     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006111211     Document Type: Editorial

References (25)

1. Pouyssegur J, Dayan F, Mazure NM: Hypoxia signaling in cancer and approaches to enforce tumour regression. Nature 441: 437-443, 2006
2. Marx J: How cells endure low oxygen. Science 303: 1454-1456, 2003
3. Nangaku M: Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure. J Am Soc Nephrol 17: 17-25, 2006
4. Eckardt KU, Bernhardt W, Weidemann A, Warnecke C, Rosenberger C, Wiesener MS, Willam C: Role of hypoxia in the pathogenesis of renal disease. Kidney Int Suppl 99: S46-S51, 2005
5. Norman JT, Fine LG: Intrarenal oxygenation in chronic renal failure. Clin Exp Pharmacol Physiol 33: 989-996, 2006
6. Mason RP: Non-invasive assessment of kidney oxygenation: A role for BOLD MRI. Kidney Int 70: 10-11, 2006
7. Prasad PV: Evaluation of intra-renal oxygenation by BOLD MRI. Nephron Clin Pract 103: c58-c65, 2006
8. Baan C, van Gelder T, Peeters A, Mol W, Niesters H, Weimar W, IJzermans J: Living kidney donors and hypoxia-inducible factor-1alpha. Transplantation 75: 570-571, 2003
9. Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ: The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275, 1999
10. Ohh M, Takagi Y, Aso T, Stebbins CE, Pavletich NP, Zbar B, Conaway RC, Conaway JW, Kaelin WG Jr: Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein. J Clin Invest 104: 1583-1591, 1999
11. Safran M, Kim WY, O'Connell F, Flippin L, Gunzler V, Horner JW, Depinho RA, Kaelin WG Jr: Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity. Assessment of an oral agent that stimulates erythropoietin production. Proc Natl Acad Sci U S A 103: 105-110, 2006
12. Tanaka T, Miyata T, Inagi R, Fujita T, Nangaku M: Hypoxia in renal disease with proteinuria and/or glomerular hypertension. Am J Pathol 165: 1979-1992, 2004
13. Rosenberger C, Mandriota S, Jurgensen JS, Wiesener MS, Horstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13: 1721-1732, 2002
14. Rosenberger C, Pratschke J, Rudolph B, Heyman SN, Schindler R, Babel N, Eckardt K-U, Frei U, Rosen S, Reinke P: Immunohistochemical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies. J Am Soc Nephrol 18: 343-351, 2007
15. Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Naenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS: HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 112: 645-657, 2003
16. Makino Y, Nakamura H, Ikeda E, Ohnuma K, Yamauchi K, Yabe Y, Poellinger L, Okada Y, Morimoto C, Tanaka H: Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells. J Immunol 171: 6534-6540, 2003
17. Kong T, Eltzschig HK, Karhausen J, Colgan SP, Shelley CS: Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression. Proc Natl Acad Sci U S A 101: 10440-10445, 2004
18. Katavetin P, Miyata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M: High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 17: 1405-1413, 2006
19. Djamali A, Sadowski E, Samaniego-Picota M, Fain SB, Muehrer RJ, Alford SK, Grist TM, Becker BN: Noninvasive assessment of early kidney allograft dysfunction by blood oxygen level-dependent magnetic resonance imaging. Transplantation 82: 621-628, 2006
20. Herrero-Fresneda I, Franquesa MA, Torras J, Vidal A, Aran J, Pluvinet R, Lloberas N, Rama I, Cruzado JM, Gulias O, Grinyo JM: Role of cold ischemia in acute rejection: Characterization of a humoral-like acute rejection in experimental renal transplantation. Transplant Proc 37: 3712-3715, 2005
21. Kouwenhoven EA, de Bruin RW, Bajema IM, Marquet RL, Ijzermans JN: Cold ischemia augments allogeneic-mediated injury in rat kidney allografts. Kidney Int 59: 1142-1148, 2001
22. Bernhardt WM, Campean V, Kany S, Jurgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Gunzler V, Amann K, Willam C, Wiesener MS, Eckardt KU: Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. J Am Soc Nephrol 17: 1970-1978, 2006
23. Matsumoto M, Makino Y, Tanaka T, Tanaka H, Ishizaka N, Noiri E, Fujita T, Nangaku M: Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. J Am Soc Nephrol 14: 1825-1832, 2003
24. Nangaku M, Kojima I, Tanaka T, Ohse T, Kato H, Fujita T: Novel drugs and the response to hypoxia: HIF stabilizers and prolyl hydroxylase. Recent Patent Rev Cardiovasc Drug Disc 1: 129-139, 2006
25. Wiesener MS, Jurgensen JS, Rosenberger C, Scholze CK, Horstrup JH, Warnecke C, Mandriota S, Bechmann I, Frei UA, Pugh CW, Ratcliffe PJ, Bachmann S, Maxwell PH, Eckardt KU: Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J 17: 271-273, 2003