메뉴 건너뛰기




Volumn 35, Issue 1, 2007, Pages 51-61

The disposition and metabolism of naveglitazar, a peroxisome proliferator-activated receptor α-γ dual, γ-dominant agonist in mice, rats, and monkeys

Author keywords

[No Author keywords available]

Indexed keywords

LY 2291229; LY 2419535; LY 591026; LY 621631; NAVEGLITAZAR; UNCLASSIFIED DRUG;

EID: 33845930050     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.012328     Document Type: Article
Times cited : (9)

References (19)
  • 1
    • 0032588487 scopus 로고    scopus 로고
    • PPARγ, the ultimate thrifty gene
    • Auwerx J (1999) PPARγ, the ultimate thrifty gene. Diabetologia 42:1033-1049.
    • (1999) Diabetologia , vol.42 , pp. 1033-1049
    • Auwerx, J.1
  • 2
    • 8744299422 scopus 로고    scopus 로고
    • Is the future bright for diabetes?
    • Bond M and Yates S (2004) Is the future bright for diabetes? South Med J 97:1027-1028.
    • (2004) South Med J , vol.97 , pp. 1027-1028
    • Bond, M.1    Yates, S.2
  • 4
    • 0033549616 scopus 로고    scopus 로고
    • Rapid rise in the incidence of type 2 diabetes from 1987 to 1996
    • Burke J, Williams K, and Gaskill S (1999) Rapid rise in the incidence of type 2 diabetes from 1987 to 1996. Arch Intern Med 159:1450-1460.
    • (1999) Arch Intern Med , vol.159 , pp. 1450-1460
    • Burke, J.1    Williams, K.2    Gaskill, S.3
  • 5
    • 0026572747 scopus 로고
    • Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: A balanced overview
    • DeFronzo R (1992) Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: a balanced overview. Diabetologia 35:389-397.
    • (1992) Diabetologia , vol.35 , pp. 389-397
    • DeFronzo, R.1
  • 6
    • 2542454565 scopus 로고    scopus 로고
    • Be fit or be sick: Peroxisome proliferator-activated receptors are down the road
    • Desvergne B, Michalik L, and Wahli W (2004) Be fit or be sick: peroxisome proliferator-activated receptors are down the road. Mol Endocrinol 18:1321-1332.
    • (2004) Mol Endocrinol , vol.18 , pp. 1321-1332
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 7
    • 0038460622 scopus 로고    scopus 로고
    • Thiazolidinediones in type 2 diabetes mellitus: Current clinical evidence
    • Diamant M and Heine R (2003) Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence. Drugs 63:1373-1405.
    • (2003) Drugs , vol.63 , pp. 1373-1405
    • Diamant, M.1    Heine, R.2
  • 9
    • 0032456709 scopus 로고    scopus 로고
    • Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: Problems and prospects
    • Ferrannini E (1998) Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: problems and prospects. Endocr Res 19:477-490.
    • (1998) Endocr Res , vol.19 , pp. 477-490
    • Ferrannini, E.1
  • 10
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller H, Dreyer C, Medin J, Mahfoudi A, Ozato K, and Wahli W (1993) Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci USA 90:2160-2164.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 11
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, and Wahli W (2000) Roles of PPARs in health and disease. Nature (Lond) 405:421-424.
    • (2000) Nature (Lond) , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 12
    • 0023431327 scopus 로고
    • Comparative metabolism and excretion of resorcinol in male and female rats
    • Kim Y and Matthews H (1987) Comparative metabolism and excretion of resorcinol in male and female rats. Fundam Appl Toxicol 9:409-414.
    • (1987) Fundam Appl Toxicol , vol.9 , pp. 409-414
    • Kim, Y.1    Matthews, H.2
  • 13
    • 0024787109 scopus 로고
    • Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs-1
    • Knihinicki R, Williams K, and Day R (1989) Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs-1. Biochem Pharmacol 38:4389-4395.
    • (1989) Biochem Pharmacol , vol.38 , pp. 4389-4395
    • Knihinicki, R.1    Williams, K.2    Day, R.3
  • 14
    • 22144477183 scopus 로고    scopus 로고
    • Ligands to peroxisome proliferator activated receptors as therapeutic options for metabolic syndrome
    • Liu Y and Reifel-Miller A (2005) Ligands to peroxisome proliferator activated receptors as therapeutic options for metabolic syndrome. Drug Discov Today Ther Strategies 2:165-169.
    • (2005) Drug Discov Today Ther Strategies , vol.2 , pp. 165-169
    • Liu, Y.1    Reifel-Miller, A.2
  • 15
    • 0033857387 scopus 로고    scopus 로고
    • Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists
    • Olefsky J (2000) Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists. J Clin Investig 106:467-472.
    • (2000) J Clin Investig , vol.106 , pp. 467-472
    • Olefsky, J.1
  • 17
    • 8744290951 scopus 로고    scopus 로고
    • Type 2 diabetes: Epidemiologic trends, evolving pathogenic concepts, and recent changes in therapeutic approach
    • Rizvi A (2004) Type 2 diabetes: epidemiologic trends, evolving pathogenic concepts, and recent changes in therapeutic approach. South Med J 97:1079-1087.
    • (2004) South Med J , vol.97 , pp. 1079-1087
    • Rizvi, A.1
  • 18
    • 0034681773 scopus 로고    scopus 로고
    • Thiazolidinediones: An update
    • Schoonjans K and Auwerx J (2000) Thiazolidinediones: an update. Lancet 355:1008-1010.
    • (2000) Lancet , vol.355 , pp. 1008-1010
    • Schoonjans, K.1    Auwerx, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.