-
1
-
-
33845874994
-
-
Moore MJ, Goldstein D, Hamm J et al (2005) Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trial Group (NCIC-CTG). In: Proceedings of the 2005 Gastrointestinal Cancers Symposium, Hollywood, FL, USA, 3: abstr 77, 27-29 Jan 2005
-
Moore MJ, Goldstein D, Hamm J et al (2005) Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trial Group (NCIC-CTG). In: Proceedings of the 2005 Gastrointestinal Cancers Symposium, Hollywood, FL, USA, 3: abstr 77, 27-29 Jan 2005
-
-
-
-
2
-
-
29344476191
-
Phase III randomised comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer
-
abstr PS 11
-
Cunningham D, Chau I, Stocken D et al (2005) Phase III randomised comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer. Eur J Cancer 3:12 (abstr PS 11)
-
(2005)
Eur J Cancer
, vol.3
, pp. 12
-
-
Cunningham, D.1
Chau, I.2
Stocken, D.3
-
3
-
-
19944409357
-
Gemcitabine versus cisplatin, epirubicin, 5-fluorouracil, gemcitabine in advanced pancreatic cancer: A phase III trial
-
Reni M, Cordio S, Milandri C et al (2005) Gemcitabine versus cisplatin, epirubicin, 5-fluorouracil, gemcitabine in advanced pancreatic cancer: a phase III trial. Lancet Oncol 6:369-376
-
(2005)
Lancet Oncol
, vol.6
, pp. 369-376
-
-
Reni, M.1
Cordio, S.2
Milandri, C.3
-
4
-
-
0035873947
-
Definitive results of a phase II trial of PEF-G (cisplatin, epirubicin, 5-fluorouracil continuous infusion, gemcitabine) in stage IV pancreatic adenocarcinoma
-
Reni M, Passoni P, Panucci MG et al (2001) Definitive results of a phase II trial of PEF-G (cisplatin, epirubicin, 5-fluorouracil continuous infusion, gemcitabine) in stage IV pancreatic adenocarcinoma. J Clin Oncol 19:2679-2686
-
(2001)
J Clin Oncol
, vol.19
, pp. 2679-2686
-
-
Reni, M.1
Passoni, P.2
Panucci, M.G.3
-
5
-
-
8244254377
-
Improvement in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA III, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR et al (1997) Improvement in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15:2403-2413
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
-
6
-
-
0036682041
-
Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
-
Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DG, Benson AB (2002) Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 20:3270-3275
-
(2002)
J Clin Oncol
, vol.20
, pp. 3270-3275
-
-
Berlin, J.D.1
Catalano, P.2
Thomas, J.P.3
Kugler, J.W.4
Haller, D.G.5
Benson, A.B.6
-
7
-
-
0141688333
-
Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore MJ, Hamm J, Dancey J, Eisenberg PD, Dagenais M, Fields A et al (2003) Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 21:3296-3302
-
(2003)
J Clin Oncol
, vol.21
, pp. 3296-3302
-
-
Moore, M.J.1
Hamm, J.2
Dancey, J.3
Eisenberg, P.D.4
Dagenais, M.5
Fields, A.6
-
8
-
-
4644327989
-
Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
-
Rocha Lima CMS, Green MR, Rotche R, Miller WH Jr, Jeffrey GM, Cisar LA et al (2004) Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 22:3776-3783
-
(2004)
J Clin Oncol
, vol.22
, pp. 3776-3783
-
-
Rocha Lima, C.M.S.1
Green, M.R.2
Rotche, R.3
Miller Jr, W.H.4
Jeffrey, G.M.5
Cisar, L.A.6
-
9
-
-
0037100983
-
A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
-
Bramhall SR, Schultz J, Nemunaitis J, Brown PD, Baillet M, Buckels JAC (2002) A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer. Br J Cancer 87:161-167
-
(2002)
Br J Cancer
, vol.87
, pp. 161-167
-
-
Bramhall, S.R.1
Schultz, J.2
Nemunaitis, J.3
Brown, P.D.4
Baillet, M.5
Buckels, J.A.C.6
-
10
-
-
0035424135
-
Marimastat as first-line therapy for patients with unresectable pancreatic cancer: A randomized trial
-
for the Marimastat Pancreatic Cancer Study Group
-
Bramhall SR, Rosemurgy A, Brown PD, Bowry C, Buckels JA, for the Marimastat Pancreatic Cancer Study Group (2001) Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial. J Clin Oncol 19:3477-3455
-
(2001)
J Clin Oncol
, vol.19
, pp. 3477-3455
-
-
Bramhall, S.R.1
Rosemurgy, A.2
Brown, P.D.3
Bowry, C.4
Buckels, J.A.5
-
11
-
-
1542358227
-
A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic adenocarcinoma
-
abstr 1003
-
Heinemann V, Quietzsch D, Gieseler F, Gonnermann N, Schonekas H, Rost A, et al. (2003) A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic adenocarcinoma. Proc Am Soc Clin Oncol 22 (abstr 1003)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Heinemann, V.1
Quietzsch, D.2
Gieseler, F.3
Gonnermann, N.4
Schonekas, H.5
Rost, A.6
-
12
-
-
2342645506
-
Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
-
Van Cutsem E, van de Velde H, Karasek P, Oettle H, Vervenne WL, Szawlowski A et al (2004) Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer. J Clin Oncol 22:1430-1438
-
(2004)
J Clin Oncol
, vol.22
, pp. 1430-1438
-
-
Van Cutsem, E.1
van de Velde, H.2
Karasek, P.3
Oettle, H.4
Vervenne, W.L.5
Szawlowski, A.6
-
13
-
-
20644464360
-
Gemcitabine in combination with Oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: Results of a GERCOR and GISCAD phase III trial
-
Louvet C, Labianca R, Hammel P, Lledo G, Zampino MG, André T, Zaniboni A, Ducreux M, Aitini E, Taïeb J, Faroux R, Lepere C, de Gramont A (2005) Gemcitabine in combination with Oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial. J Clin Oncol 23:3509-3516
-
(2005)
J Clin Oncol
, vol.23
, pp. 3509-3516
-
-
Louvet, C.1
Labianca, R.2
Hammel, P.3
Lledo, G.4
Zampino, M.G.5
André, T.6
Zaniboni, A.7
Ducreux, M.8
Aitini, E.9
Taïeb, J.10
Faroux, R.11
Lepere, C.12
de Gramont, A.13
-
14
-
-
16444384413
-
A randomized phase III trial of DX-8951f (exatecan mesylate) and gemcitabine vs. gemcitabine alone in advanced pancreatic cancer
-
abstr 4006
-
O'Reilly EM, Abou-Alfa GK, Letorneau R, Harker WG, Modiano M, Hurwitz H et al (2004) A randomized phase III trial of DX-8951f (exatecan mesylate) and gemcitabine vs. gemcitabine alone in advanced pancreatic cancer. Proc Am Soc Clin Oncol 23 (abstr 4006)
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
O'Reilly, E.M.1
Abou-Alfa, G.K.2
Letorneau, R.3
Harker, W.G.4
Modiano, M.5
Hurwitz, H.6
-
15
-
-
27144530079
-
A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer
-
Oettle H, Richards DA, Ramanathan R, Van Laethem JL, Peeters M, Fuchs M et al (2005) A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer. Ann Oncol 16:1639-1645
-
(2005)
Ann Oncol
, vol.16
, pp. 1639-1645
-
-
Oettle, H.1
Richards, D.A.2
Ramanathan, R.3
Van Laethem, J.L.4
Peeters, M.5
Fuchs, M.6
-
16
-
-
18744367197
-
Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naive patients with advanced pancreatic cancer (APC)
-
abstr 4005, 314s
-
Cheverton P, Friess H, Andras C et al (2004) Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naive patients with advanced pancreatic cancer (APC). Proc Am Soc Clin Oncol 23:314s (abstr 4005)
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
Cheverton, P.1
Friess, H.2
Andras, C.3
-
17
-
-
33845914400
-
Intensified PEFG regimen in stage III-IV pancreatic adenocarcinoma
-
abstr 919
-
Dell'Oro S, Reni M, Bonetto E et al (2004) Intensified PEFG regimen in stage III-IV pancreatic adenocarcinoma. Ann Oncol 15:242 (abstr 919)
-
(2004)
Ann Oncol
, vol.15
, pp. 242
-
-
Dell'Oro, S.1
Reni, M.2
Bonetto, E.3
-
18
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhaur EA, Wanders J, Kaplan RS, Rubinstein L et al (2004) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92(3):205-216
-
(2004)
J Natl Cancer Inst
, vol.92
, Issue.3
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhaur, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
-
19
-
-
0025195396
-
Comprehensive criteria for assessing therapy-induced toxicity
-
Ajani JA, Welch SR, Raber MN, Fields WS, Krakoff IH (1990) Comprehensive criteria for assessing therapy-induced toxicity. Cancer Invest 8:147-159
-
(1990)
Cancer Invest
, vol.8
, pp. 147-159
-
-
Ajani, J.A.1
Welch, S.R.2
Raber, M.N.3
Fields, W.S.4
Krakoff, I.H.5
-
20
-
-
23844495516
-
Final results of a prospective trial of a PEFG (cisplatin, epirubicin, 5-fluorouracil, gemcitabine) regimen followed by radiotherapy after curative surgery for pancreatic adenocarcinoma
-
Reni M, Passoni P, Bonetto E et al (2005) Final results of a prospective trial of a PEFG (cisplatin, epirubicin, 5-fluorouracil, gemcitabine) regimen followed by radiotherapy after curative surgery for pancreatic adenocarcinoma. Oncology 68:239-245
-
(2005)
Oncology
, vol.68
, pp. 239-245
-
-
Reni, M.1
Passoni, P.2
Bonetto, E.3
-
21
-
-
0027172798
-
Comparison of single agent epirubicin and 5-FU/epirubicin/mitomycin in patients with advanced adenocarcinoma of the pancreas
-
Topham C, Glees J, Coombs R et al (1993) Comparison of single agent epirubicin and 5-FU/epirubicin/mitomycin in patients with advanced adenocarcinoma of the pancreas. Oncology 50:78-83
-
(1993)
Oncology
, vol.50
, pp. 78-83
-
-
Topham, C.1
Glees, J.2
Coombs, R.3
-
22
-
-
0021927526
-
Phase II study of epirubicin in advanced adenocarcinoma of the pancreas
-
Wils JA, Bleiberg H, Blijham G et al (1985) Phase II study of epirubicin in advanced adenocarcinoma of the pancreas. Eur J Cancer 21:191-194
-
(1985)
Eur J Cancer
, vol.21
, pp. 191-194
-
-
Wils, J.A.1
Bleiberg, H.2
Blijham, G.3
-
23
-
-
0027234993
-
Activity of cisplatin in adenocarcinoma of the pancreas
-
Wils JA, Kok T, Wagener DJ et al (1993) Activity of cisplatin in adenocarcinoma of the pancreas. Eur J Cancer 29A:203-204
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 203-204
-
-
Wils, J.A.1
Kok, T.2
Wagener, D.J.3
-
24
-
-
0037099604
-
Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer
-
Maisey N, Chau I, Cunningham D, Norman A, Seymour M, Hickish T et al (2002) Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer. J Clin Oncol 20:3130-3136
-
(2002)
J Clin Oncol
, vol.20
, pp. 3130-3136
-
-
Maisey, N.1
Chau, I.2
Cunningham, D.3
Norman, A.4
Seymour, M.5
Hickish, T.6
-
25
-
-
0033012340
-
Phase II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer
-
Hidalgo M, Castellano D, Paz-Ares L et al (1999) Phase II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer. J Clin Oncol 17:585-592
-
(1999)
J Clin Oncol
, vol.17
, pp. 585-592
-
-
Hidalgo, M.1
Castellano, D.2
Paz-Ares, L.3
-
26
-
-
0026066795
-
Continuous infusion 5-fluorouracil plus weekly cisplatin for pancreatic adenocarcinoma: A Mid-Atlantic Oncology Program study
-
Rothman H, Cantrell JE, Lokich J et al (1991) Continuous infusion 5-fluorouracil plus weekly cisplatin for pancreatic adenocarcinoma: a Mid-Atlantic Oncology Program study. Cancer 68:264-268
-
(1991)
Cancer
, vol.68
, pp. 264-268
-
-
Rothman, H.1
Cantrell, J.E.2
Lokich, J.3
-
27
-
-
0028791757
-
Cisplatin and protracted venous infusion 5-fluorouracil (CF) - good symptom relief with low toxicity in advanced pancreatic carcinoma
-
Nicolson M, Webb A, Cunningham D et al (1995) Cisplatin and protracted venous infusion 5-fluorouracil (CF) - good symptom relief with low toxicity in advanced pancreatic carcinoma. Ann Oncol 6:801-804
-
(1995)
Ann Oncol
, vol.6
, pp. 801-804
-
-
Nicolson, M.1
Webb, A.2
Cunningham, D.3
-
28
-
-
0027158414
-
Phase II study of cisplatin and 120-hour continuous infusion of 5-fluorouracil in patients with advanced pancreatic adenocarcinoma
-
Rougier P, Zarba JJ, Ducreux M et al (1993) Phase II study of cisplatin and 120-hour continuous infusion of 5-fluorouracil in patients with advanced pancreatic adenocarcinoma. Ann Oncol 4:333-336
-
(1993)
Ann Oncol
, vol.4
, pp. 333-336
-
-
Rougier, P.1
Zarba, J.J.2
Ducreux, M.3
-
29
-
-
0032804326
-
Phase II trial of gemcitabine, epirubicin and granulocyte colony-stimulating factor in patients with advanced pancreatic adenocarcinoma
-
Scheitauer W, Kornek GV, Raderer M et al (1999) Phase II trial of gemcitabine, epirubicin and granulocyte colony-stimulating factor in patients with advanced pancreatic adenocarcinoma. Br J Cancer 80:1797-1802
-
(1999)
Br J Cancer
, vol.80
, pp. 1797-1802
-
-
Scheitauer, W.1
Kornek, G.V.2
Raderer, M.3
-
30
-
-
0033635935
-
Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer
-
Heinemann V, Wilke H, Mergenthaler H-G et al (2000) Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer. Ann Oncol 11:1399-1403
-
(2000)
Ann Oncol
, vol.11
, pp. 1399-1403
-
-
Heinemann, V.1
Wilke, H.2
Mergenthaler, H.-G.3
-
31
-
-
0036668658
-
A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma
-
Ducreux M, Rougier P, Pignon JP, Douillard JY, Seitz JF, Bugat R et al (2002) A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma. Ann Oncol 13:1185-1191
-
(2002)
Ann Oncol
, vol.13
, pp. 1185-1191
-
-
Ducreux, M.1
Rougier, P.2
Pignon, J.P.3
Douillard, J.Y.4
Seitz, J.F.5
Bugat, R.6
-
32
-
-
0029900438
-
A phase II study of continuous infusion 5-fluorouracil with cisplatin and epirubicin in inoperable pancreatic cancer
-
Evans TRJ, Lofts FJ, Mensi JL et al (1996) A phase II study of continuous infusion 5-fluorouracil with cisplatin and epirubicin in inoperable pancreatic cancer. Br J Cancer 73:1260-1264
-
(1996)
Br J Cancer
, vol.73
, pp. 1260-1264
-
-
Evans, T.R.J.1
Lofts, F.J.2
Mensi, J.L.3
-
33
-
-
0042386682
-
Phase II study of gemcitabine, cisplatin, and infusional fluorouracil in advanced pancreatic cancer
-
El-Rayes BF, Zalupski MM, Shields AF et al (2003) Phase II study of gemcitabine, cisplatin, and infusional fluorouracil in advanced pancreatic cancer. J Clin Oncol 21:2920-2925
-
(2003)
J Clin Oncol
, vol.21
, pp. 2920-2925
-
-
El-Rayes, B.F.1
Zalupski, M.M.2
Shields, A.F.3
-
34
-
-
33750293070
-
Quality of life assessment in advanced pancreatic adenocarcinoma: Results from a phase III randomized trial
-
in press
-
Reni M, Bonetto E, Cordio S, Passoni P, Milandri C, Cereda S, et al. (2006) Quality of life assessment in advanced pancreatic adenocarcinoma: results from a phase III randomized trial. Pancreatology (in press)
-
(2006)
Pancreatology
-
-
Reni, M.1
Bonetto, E.2
Cordio, S.3
Passoni, P.4
Milandri, C.5
Cereda, S.6
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