Cyclooxygenase-2 and inducible nitric oxide synthase expression in thyroid neoplasms and their clinicopathological correlation

Journal of Korean Medical Science

Volumn 21, Issue 6, 2006, Pages 1064-1069

  Kim, Kyung Hee ^a   Kim, Seong Ho ^a   Seok, Hyung Kim ^b   Back, Jong Ho ^a   Park, Mee Ja ^a   Kim, Jin Man ^c  

^a Eulji University School of Medicine   (South Korea)

^b Chungbuk National University College of Medicine   (South Korea)

^c Chungnam National University College of Medicine   (South Korea)

Author keywords

Cyclooxygenase 2; Nitric Oxide Synthase Type II; Thyroid Neoplasms

Indexed keywords

EID: 33845881749     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2006.21.6.1064     Document Type: Article

References (36)

1. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, van de Putte LB, Lipsky PE. Cyclooxygenase in biology and disease. FASEB J 1998; 12: 1063-73.
2. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 1998; 38: 97-120.
3. Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, DuBois RN. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994; 107: 1183-8.
4. van Rees BP, Saukkonen K, Ristimaki A, Polkowski W, Tytgat GN, Drillenburg P, Offerhaus GJ. Cyclooxygenase-2 expression during carcinogenesis in the human stomach. J Pathol 2002; 196: 171-9.
5. Madaan S, Abel PD, Chaudhary KS, Hewitt R, Stott MA, Stamp GW, Lalani EN. Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: implications for prevention and treatment. BJU Int 2000; 86: 736-41.
6. Denkert C, Kobel M, Berger S, Siegert A, Leclere A, Trefzer U, Hauptmann S. Expression of cyclooxygenase 2 in human malignant melanoma. Cancer Res 2001; 61: 303-8.
7. Joki T, Heese O, Nikas DC, Bello L, Zhang J, Kraeft SK, Seyfried NT, Abe T, Chen LB, Carroll RS, Black PM. Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer Res 2000; 60: 4926-31.
8. Fujita H, Koshida K, Keller ET, Takahashi Y, Yoshimito T, Namiki M, Mizokami A. Cyclooxygenase-2 promotes prostate cancer progression. Prostate 2002; 53: 232-40.
9. Kamijo T, Sato T, Nagatomi Y, Kitamura T. Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines. Int J Urol 2001; 8: S35-9.
10. Fosslien E. Review: molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis. Ann Clin Lab Sci 2001; 31: 325-48.
11. Siironen P, Ristimaki A, Nordling S, Louhimo J, Haapiainen R, Haglund C. Expression of COX-2 is increased with age in papillary thyroid cancer. Histopathology 2004; 44: 490-7.
12. Cornetta AJ, Russell JP, Cunnane M, Keane WM, Rothstein JL. Cyclooxygenase-2 expression in human thyroid carcinoma and Hashimoto's thyroiditis. Laryngoscope 2002; 112: 238-42.
13. Nose F, Ichikawa T, Fujiwara M, Okayasu I. Up-regulation of cyclooxygenase-2 expression in lymphocytic thyroiditis and thyroid tumors: significant correlation with inducible nitric oxide synthase. Am J Clin Pathol 2002; 117: 546-51.
14. Specht MC, Tucker ON, Hocever M, Gonzalez D, Teng L, Fahey TJ 3rd. Cyclooxygenase-2 expression in thyroid nodules. J Clin Endocrinol Metab 2002; 87: 358-63.
15. Nathan C, Xie QW. Nitric oxide synthases: roles, tolls, and controls. Cell 1994; 78: 915-8.
16. Assurey J, Canha FQ, Lew FY, Moncada S. Feedback inhibition of nitric oxide synthase activity by nitric oxide. Br J Pharmacol 1993; 108: 833-7.
17. Duenas-Gonzalez A, Isales CM, del Mar Abad-Hernandez M, Gonzalez-Sarmiento R, Sangueza O, Rodriguez-Commes J. Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease. Mod Pathol 1997; 10: 645-9.
18. Thomsen LL, Lawton FG, Knowles RG, Beesley JE, Riveros-Moreno V, Moncada S. Nitric oxide synthase activity in human gynecological cancer. Cancer Res 1994; 54: 1352-4.
19. Son HJ, Kim YH, Park DI, Kim JJ, Rhee PL, Paik SW, Choi KW, Song SY, Rhee JC. Interaction between cyclooxygenase-2 and inducible nitric oxide synthase in gastric cancer. J Clin Gastroenterol 2001; 33: 383-8.
20. Gavilanes J, Moro MA, Lizasoain I, Lorenzo P, Perez A, Leza JC, Alvarez-Vicent JJ. Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck. Laryngoscope 1999; 109: 148-52.
21. Cobbs CS, Brenman JE, Aldape KD, Bredt DS, Israel MA. Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res 1995; 55: 727-30.
22. Thomsen LL, Miles DW. Role of nitric oxide in tumor progression: lessons from human tumors. Cancer Metastasis Rev 1998; 17: 107-18.
23. Kim YM, Talanian RV, Billiar TR. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechenisms. J Biol Chem 1997; 272: 31138-48.
24. Choe W, Kim S, Hwang TS, Lee SS. Expression of inducible nitric oxide synthase in thyroid neoplasms: immunohistochemical and molecular analysis. Pathol Int 2003; 53: 434-9.
25. Kitano H, Kitanishi T, Nakanishi Y, Suzuki M, Takeuchi E, Yazawa Y, Kitajima K, Kimura H, Tooyama I. Expression of inducible nitric oxide synthase in human thyroid papillary carcinomas. Thyroid 1999; 9: 113-7.
26. Perez-Sala D, Lamas S. Regulation of cyclooxygenase-2 expression by nitric oxide in cells. Antioxid Redox Signal 2001; 3: 231-48.
27. Kobayashi O, Miwa H, Watanabe S, Tsujii M, Dubois RN, Sato N. Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2001; 281: 688-96.
28. Ermert L, Dierkes C, Ermert M. Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors. Clin Cancer Res 2003; 9: 1604-10.
29. Sharma S, Stolina M, Yang SC, Baratelli F, Lin JF, Atianzar K, Luo J, Zhu L, Lin Y, Huang M, Dohadwala M, Batra RK, Dubinett SM. Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res 2003; 9: 961-8.
30. Oshima M, Dinchuk JE, Kargman SL, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JF, Taketo MM. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996; 87: 803-9.
31. Hayek MG, Mura C, Wu D, Beharka AA, Han SN, Paulson KE, Hwang D, Meydani SN. Enhanced expression of inducible cyclooxygenase with age in murine macrophages. J Immunol 1997; 159: 2445-51.
32. Ito Y, Yoshida H, Nakano K, Takamura Y, Miya A, Kobayashi K, Yokozawa T, Matsuzuka F, Matsuura N, Kuma K, Miyauchi A. Cyclooxygenase-2 expression in thyroid neoplasms. Histopathology 2003; 42: 492-7.
33. Sobin L, Wittekind C, eds. TNM classification of malignant tumors, 5th edn. New York: Wiley-Liss, Inc. 1997.
34. Ziche M, Morbidelli L, Choudhuri R, Zhang HT, Donnini S, Granger HJ, Bicknell R. Nitric oxide synthase lies downstream from vascular endothelial growth factor induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest 1997; 99: 2625-34.
35. Kim SJ, Lee JH, Yoon JS, Mok JO, Kim YJ, Park HK, Kim CH, Byun DW, Suh KI, Yoo MH. Immunohistochemical expression of COX-2 in thyroid nodules. Korean J Intern Med 2003; 18: 225-9.
36. Bell CD, Vidal S, Kovacs K, Horvath E, Rotondo F. An immunohistochemical survey of nine cases of medullary carcinoma of thyroid including reactivity for Cox-1 and Cox-2 enzymes. Endocr Pathol 2002; 13: 331-40.