메뉴 건너뛰기




Volumn 63, Issue 1, 2007, Pages 27-37

Total and free mycophenolic acid and its 7-O-glucuronide metabolite in Chinese adult renal transplant patients: Pharmacokinetics and application of limited sampling strategies

Author keywords

Limited sampling strategy; Mycophenolic acid; Mycophenolic acid 7 O glucuronide; Pharmacokinetics

Indexed keywords

ACETYLSALICYLIC ACID; ACICLOVIR; ALPRAZOLAM; BENAZEPRIL; CALCINEURIN INHIBITOR; CARBAMAZEPINE; CORTICOSTEROID; CYCLOSPORIN A; DRUG METABOLITE; GANCICLOVIR; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; MYCOPHENOLIC ACID 7 O GLUCURONIDE; PREDNISOLONE; PREDNISONE; RAPAMYCIN; TACROLIMUS; UNCLASSIFIED DRUG; VALACICLOVIR;

EID: 33845875993     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-006-0215-y     Document Type: Article
Times cited : (41)

References (56)
  • 1
    • 0029006409 scopus 로고
    • Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection
    • European Mycophenolate Mofetil Cooperative Study Group
    • European Mycophenolate Mofetil Cooperative Study Group (1995) Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. Lancet 345:1321-1325
    • (1995) Lancet , vol.345 , pp. 1321-1325
  • 2
    • 0006986048 scopus 로고    scopus 로고
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
    • The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group (1996) A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. Transplantation 61:1029-1037
    • (1996) Transplantation , vol.61 , pp. 1029-1037
  • 3
    • 0032573739 scopus 로고    scopus 로고
    • A study comparing mycophenolate mofetil to azathioprine in simultaneous pancreas-kidney transplantation
    • Odorico JS, Pirsch JD, Knechtle SJ, D'Alessandro AM, Sollinger HW (1998) A study comparing mycophenolate mofetil to azathioprine in simultaneous pancreas-kidney transplantation. Transplantation 66:1751-1759
    • (1998) Transplantation , vol.66 , pp. 1751-1759
    • Odorico, J.S.1    Pirsch, J.D.2    Knechtle, S.J.3    D'Alessandro, A.M.4    Sollinger, H.W.5
  • 4
    • 0038246498 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies
    • Shaw LM, Korecka M, Venkataramanan R, Goldberg L, Bloom R, Brayman KL (2003) Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies. Am J Transplant 3:534-542
    • (2003) Am J Transplant , vol.3 , pp. 534-542
    • Shaw, L.M.1    Korecka, M.2    Venkataramanan, R.3    Goldberg, L.4    Bloom, R.5    Brayman, K.L.6
  • 5
    • 0029115531 scopus 로고
    • Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group
    • Sollinger HW (1995) Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation 60:225-232
    • (1995) Transplantation , vol.60 , pp. 225-232
    • Sollinger, H.W.1
  • 7
    • 0027189955 scopus 로고
    • The design and development of an immunosuppressive drug, mycophenolate mofetil
    • Allison A, Eugu E (1993) The design and development of an immunosuppressive drug, mycophenolate mofetil. Springer Semin Immunopathol 14:353-380
    • (1993) Springer Semin Immunopathol , vol.14 , pp. 353-380
    • Allison, A.1    Eugu, E.2
  • 8
    • 0029058395 scopus 로고
    • Mycophenolic acid binding to human serum albumin: Characterization and relation to pharmacodynamics
    • Nowak I, Shaw LM (1995) Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics. Clin Chem 41:1011-1017
    • (1995) Clin Chem , vol.41 , pp. 1011-1017
    • Nowak, I.1    Shaw, L.M.2
  • 13
    • 24044460758 scopus 로고    scopus 로고
    • Characterizing the role of enterohepatic recycling in the interactions between mycophenolate mofetil and calcineurin inhibitors in renal transplant patients by pharmacokinetic modelling
    • Cremers S, Schoemaker R, Scholten E, den Hartigh J, Konig-Quartel J, van Kan E, Paul L, de Fijter J (2005) Characterizing the role of enterohepatic recycling in the interactions between mycophenolate mofetil and calcineurin inhibitors in renal transplant patients by pharmacokinetic modelling. Br J Clin Pharmacol 60:249-256
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 249-256
    • Cremers, S.1    Schoemaker, R.2    Scholten, E.3    den Hartigh, J.4    Konig-Quartel, J.5    van Kan, E.6    Paul, L.7    de Fijter, J.8
  • 14
    • 0033954783 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolate mofetil are influenced by concomitant immunosuppression
    • Filler G, Zimmering M, Mai I (2000) Pharmacokinetics of mycophenolate mofetil are influenced by concomitant immunosuppression. Pediatr Nephrol 14:100-104
    • (2000) Pediatr Nephrol , vol.14 , pp. 100-104
    • Filler, G.1    Zimmering, M.2    Mai, I.3
  • 16
    • 0038298273 scopus 로고    scopus 로고
    • Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: A prospective study in 100 de novo renal allograft recipients
    • Kuypers DR, Claes K, Evenepoel P, Maes B, Coosemans W, Pirenne J, Vanrenterghem Y (2003) Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: a prospective study in 100 de novo renal allograft recipients. J Clin Pharmacol 43:866-880
    • (2003) J Clin Pharmacol , vol.43 , pp. 866-880
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3    Maes, B.4    Coosemans, W.5    Pirenne, J.6    Vanrenterghem, Y.7
  • 21
    • 0035189304 scopus 로고    scopus 로고
    • Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: Preliminary report
    • Shipkova M, Armstrong VW, Kuypers D, Perner F, Fabrizi V, Holzer H, Wieland E, Oellerich M (2001) Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: preliminary report. Ther Drug Monit 23:717-721
    • (2001) Ther Drug Monit , vol.23 , pp. 717-721
    • Shipkova, M.1    Armstrong, V.W.2    Kuypers, D.3    Perner, F.4    Fabrizi, V.5    Holzer, H.6    Wieland, E.7    Oellerich, M.8
  • 22
    • 0035086852 scopus 로고    scopus 로고
    • Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
    • van Gelder T, Klupp J, Barten MJ, Christians U, Morris RE (2001) Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit 23:119-128
    • (2001) Ther Drug Monit , vol.23 , pp. 119-128
    • van Gelder, T.1    Klupp, J.2    Barten, M.J.3    Christians, U.4    Morris, R.E.5
  • 23
    • 0031917826 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function
    • Shaw LM, Mick R, Nowak I, Korecka M, Brayman KL (1998) Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function. J Clin Pharmacol 38:268-275
    • (1998) J Clin Pharmacol , vol.38 , pp. 268-275
    • Shaw, L.M.1    Mick, R.2    Nowak, I.3    Korecka, M.4    Brayman, K.L.5
  • 24
    • 25844525727 scopus 로고    scopus 로고
    • The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid doseinterval exposure in de novo renal allograft recipients
    • Kuypers DR, Naesens M, Vermeire S, Vanrenterghem Y (2005) The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid doseinterval exposure in de novo renal allograft recipients. Clin Pharmacol Ther 78:351-361
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 351-361
    • Kuypers, D.R.1    Naesens, M.2    Vermeire, S.3    Vanrenterghem, Y.4
  • 25
    • 2042515610 scopus 로고    scopus 로고
    • Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients
    • Kuypers DR, Claes K, Evenepoel P, Maes B, Vanrenterghem Y (2004) Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients. Clin Pharmacol Ther 75:434-447
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 434-447
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3    Maes, B.4    Vanrenterghem, Y.5
  • 26
    • 7044226007 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid after a single and multiple oral doses of mycophenolate mofetil in Chinese renal transplant recipients
    • Liang MZ, Lu YP, Nan F, Yu Q, Qin YP, Zou YG (2004) Pharmacokinetics of mycophenolic acid after a single and multiple oral doses of mycophenolate mofetil in Chinese renal transplant recipients. Transplant Proc 36:2065-2067
    • (2004) Transplant Proc , vol.36 , pp. 2065-2067
    • Liang, M.Z.1    Lu, Y.P.2    Nan, F.3    Yu, Q.4    Qin, Y.P.5    Zou, Y.G.6
  • 27
    • 26844463990 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid in Chinese kidney transplant patients
    • Lu XY, Huang HF, Sheng-Tu JZ, Liu J (2005) Pharmacokinetics of mycophenolic acid in Chinese kidney transplant patients. J Zhejiang Univ Sci B 6:885-891
    • (2005) J Zhejiang Univ Sci B , vol.6 , pp. 885-891
    • Lu, X.Y.1    Huang, H.F.2    Sheng-Tu, J.Z.3    Liu, J.4
  • 28
    • 0035148545 scopus 로고    scopus 로고
    • Correlation of mycophenolic acid pharmacokinetic parameters with side effects in kidney transplant patients treated with mycophenolate mofetil
    • Mourad M, Malaise J, Chaib Eddour D, De Meyer M, Konig J, Schepers R, Squifflet JP, Wallemacq P (2001) Correlation of mycophenolic acid pharmacokinetic parameters with side effects in kidney transplant patients treated with mycophenolate mofetil. Clin Chem 47:88-94
    • (2001) Clin Chem , vol.47 , pp. 88-94
    • Mourad, M.1    Malaise, J.2    Chaib Eddour, D.3    De Meyer, M.4    Konig, J.5    Schepers, R.6    Squifflet, J.P.7    Wallemacq, P.8
  • 29
    • 12944260647 scopus 로고    scopus 로고
    • Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients
    • Oellerich M, Shipkova M, Schutz E, Wieland E, Weber L, Tonshoff B, Armstrong VW (2000) Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: implications for therapeutic drug monitoring. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. Ther Drug Monit 22:20-26
    • (2000) Ther Drug Monit , vol.22 , pp. 20-26
    • Oellerich, M.1    Shipkova, M.2    Schutz, E.3    Wieland, E.4    Weber, L.5    Tonshoff, B.6    Armstrong, V.W.7
  • 31
    • 9644281481 scopus 로고    scopus 로고
    • Mycophenolic acid in diabetic renal transplant recipients: Pharmacokinetics and application of a limited sampling strategy
    • van Hest RM, Mathot RA, Vulto AG, Le Meur Y, van Gelder T (2004) Mycophenolic acid in diabetic renal transplant recipients: pharmacokinetics and application of a limited sampling strategy. Ther Drug Monit 26:620-625
    • (2004) Ther Drug Monit , vol.26 , pp. 620-625
    • van Hest, R.M.1    Mathot, R.A.2    Vulto, A.G.3    Le Meur, Y.4    van Gelder, T.5
  • 32
    • 0032858574 scopus 로고    scopus 로고
    • Area under the plasma concentration-time curve for total, but not for free, mycophenolic acid increases in the stable phase after renal transplantation: A longitudinal study in pediatric patients. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients
    • Weber LT, Lamersdorf T, Shipkova M, Niedmann PD, Wiesel M, Zimmerhackl LB, Staskewitz A, Schutz E, Mehls O, Oellerich M, Armstrong VW, Tonshoff B (1999) Area under the plasma concentration-time curve for total, but not for free, mycophenolic acid increases in the stable phase after renal transplantation: a longitudinal study in pediatric patients. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. Ther Drug Monit 21:498-506
    • (1999) Ther Drug Monit , vol.21 , pp. 498-506
    • Weber, L.T.1    Lamersdorf, T.2    Shipkova, M.3    Niedmann, P.D.4    Wiesel, M.5    Zimmerhackl, L.B.6    Staskewitz, A.7    Schutz, E.8    Mehls, O.9    Oellerich, M.10    Armstrong, V.W.11    Tonshoff, B.12
  • 33
    • 0036191888 scopus 로고    scopus 로고
    • The pharmacokinetic- pharmacodynamic relationship for total and free mycophenolic acid in pediatric renal transplant recipients: A report of the German Study Group on Mycophenolate Mofetil Therapy
    • Weber LT, Shipkova M, Armstrong VW, Wagner N, Schutz E, Mehls O, Zimmerhackl LB, Oellerich M, Tonshoff B (2002) The pharmacokinetic- pharmacodynamic relationship for total and free mycophenolic acid in pediatric renal transplant recipients: a report of the German Study Group on Mycophenolate Mofetil Therapy. J Am Soc Nephrol 13:759-768
    • (2002) J Am Soc Nephrol , vol.13 , pp. 759-768
    • Weber, L.T.1    Shipkova, M.2    Armstrong, V.W.3    Wagner, N.4    Schutz, E.5    Mehls, O.6    Zimmerhackl, L.B.7    Oellerich, M.8    Tonshoff, B.9
  • 36
    • 7044222701 scopus 로고    scopus 로고
    • The pharmacokinetics of mycophenolate mofetil in Thai kidney transplant recipients
    • Jirasiritham S, Sumethkul V, Mavichak V, Na-Bangchang K (2004) The pharmacokinetics of mycophenolate mofetil in Thai kidney transplant recipients. Transplant Proc 36:2076-2078
    • (2004) Transplant Proc , vol.36 , pp. 2076-2078
    • Jirasiritham, S.1    Sumethkul, V.2    Mavichak, V.3    Na-Bangchang, K.4
  • 37
    • 0033665086 scopus 로고    scopus 로고
    • Efficacy and safety of mycophenolate mofetil in different dosages in Asian renal allograft recipients
    • Tsang WK, Tong KL, Yeung S, Lee W, Chan HW (2000) Efficacy and safety of mycophenolate mofetil in different dosages in Asian renal allograft recipients. Transplant Proc 32:1755-1756
    • (2000) Transplant Proc , vol.32 , pp. 1755-1756
    • Tsang, W.K.1    Tong, K.L.2    Yeung, S.3    Lee, W.4    Chan, H.W.5
  • 38
    • 0032210180 scopus 로고    scopus 로고
    • Immunosuppressive effect of mycophenolate mofetil with two different dosages in cadaveric renal transplantation: A short study
    • Wang X, Tang X, Xu D (1998) Immunosuppressive effect of mycophenolate mofetil with two different dosages in cadaveric renal transplantation: a short study. Transplant Proc 30:3573-3574
    • (1998) Transplant Proc , vol.30 , pp. 3573-3574
    • Wang, X.1    Tang, X.2    Xu, D.3
  • 39
    • 0033673964 scopus 로고    scopus 로고
    • Safety and efficacy of mycophenolate mofetil for prophylaxis in Asian renal transplant recipients
    • Suhail SM, Vathsala A, Lou HX, Woo KT (2000) Safety and efficacy of mycophenolate mofetil for prophylaxis in Asian renal transplant recipients. Transplant Proc 32:1757-1758
    • (2000) Transplant Proc , vol.32 , pp. 1757-1758
    • Suhail, S.M.1    Vathsala, A.2    Lou, H.X.3    Woo, K.T.4
  • 41
    • 0034897144 scopus 로고    scopus 로고
    • Current issues in therapeutic drug monitoring of mycophenolic acid: Report of a roundtable discussion
    • Shaw LM, Holt DW, Oellerich M, Meiser B, van Gelder T (2001) Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussion. Ther Drug Monit 23:305-315
    • (2001) Ther Drug Monit , vol.23 , pp. 305-315
    • Shaw, L.M.1    Holt, D.W.2    Oellerich, M.3    Meiser, B.4    van Gelder, T.5
  • 43
    • 26844456521 scopus 로고    scopus 로고
    • Simple high-performance liquid chromatographic assay, with post-column derivatization, for simultaneous determination of mycophenolic acid and its glucuronide metabolite in human plasma and urine
    • Jiao Z, Zhong Y, Shen J, Yu YQ (2005) Simple high-performance liquid chromatographic assay, with post-column derivatization, for simultaneous determination of mycophenolic acid and its glucuronide metabolite in human plasma and urine. Chromatographia 62:363-371
    • (2005) Chromatographia , vol.62 , pp. 363-371
    • Jiao, Z.1    Zhong, Y.2    Shen, J.3    Yu, Y.Q.4
  • 44
    • 84945737762 scopus 로고
    • A leisurely look at the bootstrap, the jackknife, and cross-validation
    • Efron B, Gong G (1983) A leisurely look at the bootstrap, the jackknife, and cross-validation. Amer Stat 37:36-48
    • (1983) Amer Stat , vol.37 , pp. 36-48
    • Efron, B.1    Gong, G.2
  • 45
    • 0015971972 scopus 로고
    • The jackknife - a review
    • Miller R (1974) The jackknife - a review. Biometrika 61:1-15
    • (1974) Biometrika , vol.61 , pp. 1-15
    • Miller, R.1
  • 46
    • 0019604592 scopus 로고
    • Some suggestions for measuring predictive performance
    • Sheiner LB, Beal SL (1981) Some suggestions for measuring predictive performance. J Pharmacokinet Biopharm 9:503-512
    • (1981) J Pharmacokinet Biopharm , vol.9 , pp. 503-512
    • Sheiner, L.B.1    Beal, S.L.2
  • 47
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307-310
    • (1986) Lancet , vol.1 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 48
    • 0038442626 scopus 로고    scopus 로고
    • Automated determination of free mycophenolic acid and its glucuronide in plasma from renal allograft recipients
    • Mandla R, Line PD, Midtvedt K, Bergan S (2003) Automated determination of free mycophenolic acid and its glucuronide in plasma from renal allograft recipients. Ther Drug Monit 25:407-414
    • (2003) Ther Drug Monit , vol.25 , pp. 407-414
    • Mandla, R.1    Line, P.D.2    Midtvedt, K.3    Bergan, S.4
  • 49
    • 0031460242 scopus 로고    scopus 로고
    • Influence of race or ethnicity on pharmacokinetics of drugs
    • Johnson JA (1997) Influence of race or ethnicity on pharmacokinetics of drugs. J Pharm Sci 86:1328-1333
    • (1997) J Pharm Sci , vol.86 , pp. 1328-1333
    • Johnson, J.A.1
  • 52
    • 0034042130 scopus 로고    scopus 로고
    • Limited sampling strategy for mycophenolic acid area under the curve
    • Filler G, Mai I (2000) Limited sampling strategy for mycophenolic acid area under the curve. Ther Drug Monit 22:169-173
    • (2000) Ther Drug Monit , vol.22 , pp. 169-173
    • Filler, G.1    Mai, I.2
  • 53
    • 0035712708 scopus 로고    scopus 로고
    • Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy
    • Le Guellec C, Buchler M, Giraudeau B, Le Meur Y, Gakoue JE, Lebranchu Y, Marquet P, Paintaud G (2002) Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy. Eur J Clin Pharmacol 57:805-811
    • (2002) Eur J Clin Pharmacol , vol.57 , pp. 805-811
    • Le Guellec, C.1    Buchler, M.2    Giraudeau, B.3    Le Meur, Y.4    Gakoue, J.E.5    Lebranchu, Y.6    Marquet, P.7    Paintaud, G.8
  • 54
    • 0036721306 scopus 로고    scopus 로고
    • Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus
    • Pawinski T, Hale M, Korecka M, Fitzsimmons WE, Shaw LM (2002) Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus. Clin Chem 48:1497-1504
    • (2002) Clin Chem , vol.48 , pp. 1497-1504
    • Pawinski, T.1    Hale, M.2    Korecka, M.3    Fitzsimmons, W.E.4    Shaw, L.M.5
  • 55
    • 0032812557 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of total and free mycophenolic acid (MPA) and limited sampling strategy for determination of MPA-AUC in paediatric renal transplant recipients. The German Study Group on Mycophenolate Mofetil (MMF) Therapy
    • Weber LT, Schutz E, Lamersdorf T, Shipkova M, Niedmann PD, Oellerich M, Zimmerhackl LB, Staskewitz A, Mehls O, Armstrong VW, Tonshoff B (1999) Therapeutic drug monitoring of total and free mycophenolic acid (MPA) and limited sampling strategy for determination of MPA-AUC in paediatric renal transplant recipients. The German Study Group on Mycophenolate Mofetil (MMF) Therapy. Nephrol Dial Transplant 14 Suppl 4:34-35
    • (1999) Nephrol Dial Transplant , vol.14 , Issue.SUPPL. 4 , pp. 34-35
    • Weber, L.T.1    Schutz, E.2    Lamersdorf, T.3    Shipkova, M.4    Niedmann, P.D.5    Oellerich, M.6    Zimmerhackl, L.B.7    Staskewitz, A.8    Mehls, O.9    Armstrong, V.W.10    Tonshoff, B.11
  • 56
    • 0033797428 scopus 로고    scopus 로고
    • Evaluation of limited sampling strategies for estimation of 12-hour mycophenolic acid area under the plasma concentration-time curve in adult renal transplant patients
    • Willis C, Taylor PJ, Salm P, Tett SE, Pillans PI (2000) Evaluation of limited sampling strategies for estimation of 12-hour mycophenolic acid area under the plasma concentration-time curve in adult renal transplant patients. Ther Drug Monit 22:549-554
    • (2000) Ther Drug Monit , vol.22 , pp. 549-554
    • Willis, C.1    Taylor, P.J.2    Salm, P.3    Tett, S.E.4    Pillans, P.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.