Influence of race or ethnicity on pharmacokinetics of drugs

Journal of Pharmaceutical Sciences

Volumn 86, Issue 12, 1997, Pages 1328-1333

  Johnson, Julie A ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPRAZOLAM; BENZOIC ACID; CAFFEINE; DESIPRAMINE; DIAZEPAM; DIPHENHYDRAMINE; DISOPYRAMIDE; METHYLPREDNISOLONE; METOPROLOL; MORPHINE; NIFEDIPINE; OMEPRAZOLE; PHENYTOIN; PROPRANOLOL; QUINIDINE; SALICYLIC ACID; TRIAZOLAM; TRIMAZOSIN; WARFARIN;

CHINESE; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ETHNIC GROUP; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LIVER METABOLISM; MALE; NEGRO; ORAL DRUG ADMINISTRATION; RACE DIFFERENCE; REVIEW;

EID: 0031460242     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9702168     Document Type: Article

References (36)

1. Wood, A. J. J.; Zhou, H. H. Ethnic differences in drug disposition and responsiveness. Clin. Pharmacokinet 1991, 20, 350-73.
2. Svensson, C. K. Representation of American blacks in clinical trials of new drugs. J. Am. Med. Assoc. 1989, 261, 263-65.
3. Inclusion of minorities in study population. NIH Guide 1988, 17, 2-3.
4. Sowinski, K. M.; Lima, J. J.; Burlew, B. S.; Massie, J. D.; Johnson, J. A. Racial differences in propranolol enantiomer kinetics following simultaneous i.v. and oral administration. Br. J. Clin. Pharmacol. 1996, 42, 339-46.
5. Lin, K. M.; Lau, J. K.; Smith, R.; Phillips, P.; Antal, W.; Poland, R. E. Comparison of alprazolam plasma levels in normal Asian and Caucasian male volunteers. Psychopharmacology 1988, 96, 365-369.
6. 1-adrenoceptor responses in normotensive Caucasians and West Africans. Br. J. Clin. Pharmacol. 1986, 21, 401-408.
7. Lotte, C.; Wester, R. C.; Rougier, A.; Maibach, H. I. Racial differences in the in vivo percutaneous absorption of some organic compounds: A comparison between black, Caucasian and Asian subjects. Arch. Dermatol. Res. 1993, 284, 456.
8. Abrams, S. A.; O'Brien, K. O.; Liang, L. K.; Stuff, J. E. Differences in calcium absorption and kinetics between black and white girls aged 5-16 years. J. Bone Miner. Res. 1995, 10, 829-33.
9. Lindholm, A.; Welsh, M.; Alton, C.; Kahan, B. D. Demographic factors influencing cyclosporine pharmacokinetic parameters in patients with uremia: Racial differences in bioavailability. Clin. Pharmacol. Ther. 1992, 52, 359-71.
10. Lown, K. S.; Mayo, R. R.; Leichtman, A.B.; Hsiao, H. L.; Turgeon, D. K.; Schmiedlin-Ren, P.; Brown, M. B.; Guo, W.; Rossi, S. J.; Benet, L. Z.; Watkins, P, B. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine Clin. Pharmacol. Ther. 1997, 62, 248-260.
11. Johnson, J. A.; Burlew, B. S. Racial differences in propranolol pharmacokinetics. Clin. Pharmacol. Ther. 1992, 51, 495-500.
12. Herve, F.; Urien, S.; Albengres, E.; Duche, J. C.; Tillement, J. P. Drug binding in plasma. A summary of recent trends in the study of drug and hormone binding. Clin. Pharmacokinet. 1994, 26, 44-58.
13. Zhou, H. H.; Adedoyin A.; Wilkinson, G. R. Differences in plasma binding of drugs between Caucasians and Chinese subjects. Clin. Pharmacol. Ther. 1990, 48, 10-17.
14. Johnson, J. A.; Livingston, T. N. Differences between blacks and whites in plasma protein binding of drugs. Eur. J. Clin. Pharmacol. 1997, 51, 485-488.
15. 1-acid glycoprotein concentration. Ir. J. Med. Sci. 1995, 164, 26-7.
16. Tornatore, K. M.; Biocevich, D. M.; Reed, K.; Tousley, K.; Singh, J. P.; Venuto, R. C. Methylprednisolone pharmacokinetics, cortisol response, and adverse effects in black and white renal transplant recipients. Transplantation 1995, 59, 729-736.
17. Zhou, H. H.; Koshakji, R. P.; Silberstein, D. J.; Wilkinson, G. R.; Wood, A. J. J. Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American Whites. N. Engl. J. Med. 1989, 320, 565-70.
18. Zhou, H. H.; Sheller, J. R.; Nu, H.; Wood, M.; Wood, A. J. J. Ethnic differences in response to morphine. Clin. Pharmacol. Ther. 1993, 54, 507-13.
19. Rudorfer, M. V.; Lane, E. A.; Chang, W. H.; Zhang, M.; Potter, W. Z. Desipramine pharmacokinetics in Chinese and Caucasian volunteers. Br. J. Clin. Pharmacol. 1984, 17, 433-440.
20. Ahsan, C. H.; Renwick, A. G.; Waller, D. G.; Challenor, V. F.; George, C. F.; Amanullah, M. The influences of dose and ethnic origins on the pharmacokinetics of nifedipine. Clin. Pharmacol. Ther. 1993, 54, 329-38.
21. Shimade, T.; Yamazaki, H.; Mimura, M.; Inui, Y.; Guengerich, F. P. Interindividual variations in human liver cytochrome p-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies of liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 1994, 270, 414-423.
22. Kinirons, M. T.; Lang, C. C.; He, H. B.; Chebreselasie, K.; shay, S.; Robin, D. W.; Wood, A. J. J. Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: Ethnicity and CYP3A activity. Br. J. Clin. Pharmacol. 1996, 41, 69-72.
23. Ghoneim, M. M.; Korttila, K.; Chiang, C. K.; Jacobs, L.; Shoenwald, R. D.; Mewaldt, S. P.; Kayaba, K. O. Diazepam effects and kinetics in Caucasians and Orientals. Clin. Pharmacol. Ther. 1981, 29, 749-756.
24. Caraco, Y.; Lagerstrom, P. O.; Wood, A. J. J. Ethnic and genetic determinants of omeprazole disposition and effect. Clin. Pharmacol. Ther. 1996, 60, 157-67.
25. Sowunmi, A.; Rashid, T. J.; Akinyinka, O. O.; Renwick, A. G. Ethnic differences in nifedipine kinetics: comparisons between Nigerians, Caucasians and South Asians. Br. J. Clin. Pharmacol. 1995, 40, 489-493.
26. Edeki, T. I.; Brase, D. A. Phenytoin disposition and toxicity: Role of pharmacogenetic and interethnic factors. Drug Metab. Rev. 1995, 27, 449-469.
27. Johnson, J. A.; Burlew, B. S. Metoprolol metabolism via CYP2D6 in ethnic populations. Drug Metab. Dispos. 1996, 24, 350-355.
28. Kaul, S.; Srinivas, N. R.; Igwemezie, L. N.; Barbhaiya, R. H. Effects of gender, age, and race on the pharmacokinetics of etoposide after intravenous administration of etoposide phosphate in cancer patients. Semin. Oncol. 1996, 23 (Suppl 13), 23-29.
29. McLeod, H. L.; Fang, L.; Luo, X.; Scott, E. P.; Evans, W. E. Ethnic differences in erythrocyte catechol-O-methyltransferase activity in black and white Americans. J. Pharmacol. Exp. Ther. 1994, 270, 26-29.
30. McLeod, H. L.; Lin, J. S.; Scott, E. P.; Pui, C. H.; Evans, W. E. Thiopurine methyltransferase activity in American white subject and black subjects. Clin. Pharmacol. Ther. 1994, 55, 15-20.
31. Relling, M. V.; Lin, J. S.; Ayers, G. D.; Evans, W. E. Racial and gender differences in N-acetyltransferase, xanthine oxidase and CYP1A2 activities. Clin. Pharmacol. Ther. 1992, 52, 643-58.
32. Relling, M. V.; Evans, W. E. Genetic polymorphisms of drug metabolism. In Applied Pharmacokinetics, 3rd ed.; Evans, W. E.; Schentag, J. J.; Jusko, W. J.; Eds.; Applied Therapeutics, Inc.: Vancouver, WA, 1992; pp 7-1 to 7-32.
33. Setiabudy, R.; Kusaka, M.; Chiba, K.; Darmansjah, I.; Ishizaki, T. Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydrpxylation polymorphisms in an Indonesian population: A cocktail and extended phenotyping assessment trial. Clin. Pharmacol. Ther. 1994, 56, 142-53.
34. Jhee, S. S.; Burm, J. P.; Gill, M. A. Comparison of aminoglycoside pharmacokinetics in Asian, Hispanic and Caucasian patients by using population pharmacokinetic methods. Antimicrob. Agents Chemother. 1994, 38, 2073-2077.
35. Sowinski, K. M.; Burlew, B. S.; Johnson, J. A. Racial differences in sensitivity to the negative chronotropic effects of propranolol in healthy males. Clin. Pharmacol. Ther. 1995, 57, 678-83.
36. Kitler, M. E. Clinical trials and transethnic pharmacology. Drug Safety 1994, 11, 378-391.