-
1
-
-
33645307384
-
The ABC protein turned chloride channel whose failure causes cystic fibrosis
-
Gadsby D.C., Vergani P., and Csanady L. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 440 (2006) 477-483
-
(2006)
Nature
, vol.440
, pp. 477-483
-
-
Gadsby, D.C.1
Vergani, P.2
Csanady, L.3
-
2
-
-
0024453308
-
Identification of the cystic fibrosis gene: chromosome walking and jumping
-
Rommens J.M., Iannuzzi M.C., Kerem B., Drumm M.L., Melmer G., Dean M., Rozmahel R., Cole J.L., Kennedy D., Hidaka N., et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 245 (1989) 1059-1065
-
(1989)
Science
, vol.245
, pp. 1059-1065
-
-
Rommens, J.M.1
Iannuzzi, M.C.2
Kerem, B.3
Drumm, M.L.4
Melmer, G.5
Dean, M.6
Rozmahel, R.7
Cole, J.L.8
Kennedy, D.9
Hidaka, N.10
-
3
-
-
0024424270
-
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA
-
Riordan J.R., Rommens J.M., Kerem B., Alon N., Rozmahel R., Grzelczak Z., Zielenski J., Lok S., Plavsic N., Chou J.L., et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245 (1989) 1066-1073
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
-
4
-
-
11444266284
-
The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR
-
Du K., Sharma M., and Lukacs G.L. The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR. Nat. Struct. Mol. Biol. 12 (2005) 17-25
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 17-25
-
-
Du, K.1
Sharma, M.2
Lukacs, G.L.3
-
5
-
-
0026781952
-
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
-
Denning G.M., Anderson M.P., Amara J.F., Marshall J., Smith A.E., and Welsh M.J. Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature 358 (1992) 761-764
-
(1992)
Nature
, vol.358
, pp. 761-764
-
-
Denning, G.M.1
Anderson, M.P.2
Amara, J.F.3
Marshall, J.4
Smith, A.E.5
Welsh, M.J.6
-
6
-
-
0027483610
-
The cystic fibrosis mutation (delta F508) does not influence the chloride channel activity of CFTR
-
Li C., Ramjeesingh M., Reyes E., Jensen T., Chang X., Rommens J.M., and Bear C.E. The cystic fibrosis mutation (delta F508) does not influence the chloride channel activity of CFTR. Nat. Genet. 3 (1993) 311-316
-
(1993)
Nat. Genet.
, vol.3
, pp. 311-316
-
-
Li, C.1
Ramjeesingh, M.2
Reyes, E.3
Jensen, T.4
Chang, X.5
Rommens, J.M.6
Bear, C.E.7
-
7
-
-
11144355340
-
Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects
-
Egan M.E., Pearson M., Weiner S.A., Rajendran V., Rubin D., Glockner-Pagel J., Canny S., Du K., Lukacs G.L., and Caplan M.J. Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects. Science 304 (2004) 600-602
-
(2004)
Science
, vol.304
, pp. 600-602
-
-
Egan, M.E.1
Pearson, M.2
Weiner, S.A.3
Rajendran, V.4
Rubin, D.5
Glockner-Pagel, J.6
Canny, S.7
Du, K.8
Lukacs, G.L.9
Caplan, M.J.10
-
9
-
-
21244494942
-
Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs
-
Wang W., Li G., Clancy J.P., and Kirk K.L. Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs. J. Biol. Chem. 280 (2005) 23622-23630
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23622-23630
-
-
Wang, W.1
Li, G.2
Clancy, J.P.3
Kirk, K.L.4
-
10
-
-
33645844261
-
Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network
-
Lipecka J., Norez C., Bensalem N., Baudouin-Legros M., Planelles G., Becq F., Edelman A., and Davezac N. Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network. J. Pharmacol. Exp. Ther. 317 (2006) 500-505
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.317
, pp. 500-505
-
-
Lipecka, J.1
Norez, C.2
Bensalem, N.3
Baudouin-Legros, M.4
Planelles, G.5
Becq, F.6
Edelman, A.7
Davezac, N.8
-
11
-
-
6044268094
-
Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells
-
Dragomir A., Bjorstad J., Hjelte L., and Roomans G.M. Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells. Biochem. Biophys. Res. Commun. 322 (2004) 447-451
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 447-451
-
-
Dragomir, A.1
Bjorstad, J.2
Hjelte, L.3
Roomans, G.M.4
-
12
-
-
7644238103
-
Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein
-
Loo T.W., Bartlett M.C., and Clarke D.M. Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein. Biochem. Biophys. Res. Commun. 325 (2004) 580-585
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.325
, pp. 580-585
-
-
Loo, T.W.1
Bartlett, M.C.2
Clarke, D.M.3
-
13
-
-
4644360693
-
Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models
-
Song Y., Sonawane N.D., Salinas D., Qian L., Pedemonte N., Galietta L.J., and Verkman A.S. Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models. J. Biol. Chem. 279 (2004) 40629-40633
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40629-40633
-
-
Song, Y.1
Sonawane, N.D.2
Salinas, D.3
Qian, L.4
Pedemonte, N.5
Galietta, L.J.6
Verkman, A.S.7
-
14
-
-
33644625310
-
SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis
-
Grubb B.R., Gabriel S.E., Mengos A., Gentzsch M., Randell S.H., Van Heeckeren A.M., Knowles M.R., Drumm M.L., Riordan J.R., and Boucher R.C. SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis. Am. J. Respir. Cell Mol. Biol. 34 (2006) 355-363
-
(2006)
Am. J. Respir. Cell Mol. Biol.
, vol.34
, pp. 355-363
-
-
Grubb, B.R.1
Gabriel, S.E.2
Mengos, A.3
Gentzsch, M.4
Randell, S.H.5
Van Heeckeren, A.M.6
Knowles, M.R.7
Drumm, M.L.8
Riordan, J.R.9
Boucher, R.C.10
-
15
-
-
18844384936
-
Processing of CFTR: traversing the cellular maze-how much CFTR needs to go through to avoid cystic fibrosis?
-
Amaral M.D. Processing of CFTR: traversing the cellular maze-how much CFTR needs to go through to avoid cystic fibrosis?. Pediatr. Pulmonol. 39 (2005) 479-491
-
(2005)
Pediatr. Pulmonol.
, vol.39
, pp. 479-491
-
-
Amaral, M.D.1
-
16
-
-
33744964145
-
Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator
-
Harada K., Okiyoneda T., Hashimoto Y., Ueno K., Nakamura K., Yamahira K., Sugahara T., Shuto T., Wada I., Suico M.A., and Kai H. Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 281 (2006) 12841-12848
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 12841-12848
-
-
Harada, K.1
Okiyoneda, T.2
Hashimoto, Y.3
Ueno, K.4
Nakamura, K.5
Yamahira, K.6
Sugahara, T.7
Shuto, T.8
Wada, I.9
Suico, M.A.10
Kai, H.11
-
17
-
-
0742270642
-
Delta F508 CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression
-
Okiyoneda T., Harada K., Takeya M., Yamahira K., Wada I., Shuto T., Suico M.A., Hashimoto Y., and Kai H. Delta F508 CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression. Mol. Biol. Cell 15 (2004) 563-574
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 563-574
-
-
Okiyoneda, T.1
Harada, K.2
Takeya, M.3
Yamahira, K.4
Wada, I.5
Shuto, T.6
Suico, M.A.7
Hashimoto, Y.8
Kai, H.9
-
18
-
-
2442439998
-
Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein
-
Suico M.A., Yoshida H., Seki Y., Uchikawa T., Lu Z., Shuto T., Matsuzaki K., Nakao M., Li J.D., and Kai H. Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein. J. Biol. Chem. 279 (2004) 19091-19098
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19091-19098
-
-
Suico, M.A.1
Yoshida, H.2
Seki, Y.3
Uchikawa, T.4
Lu, Z.5
Shuto, T.6
Matsuzaki, K.7
Nakao, M.8
Li, J.D.9
Kai, H.10
-
19
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir S.M., Lendeckel W., and Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15 (2001) 188-200
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
20
-
-
18644374442
-
Calnexin Delta 185-520 partially reverses the misprocessing of the Delta F508 cystic fibrosis transmembrane conductance regulator
-
Okiyoneda T., Wada I., Jono H., Shuto T., Yoshitake K., Nakano N., Nagayama S., Harada K., Isohama Y., Miyata T., and Kai H. Calnexin Delta 185-520 partially reverses the misprocessing of the Delta F508 cystic fibrosis transmembrane conductance regulator. FEBS Lett. 526 (2002) 87-92
-
(2002)
FEBS Lett.
, vol.526
, pp. 87-92
-
-
Okiyoneda, T.1
Wada, I.2
Jono, H.3
Shuto, T.4
Yoshitake, K.5
Nakano, N.6
Nagayama, S.7
Harada, K.8
Isohama, Y.9
Miyata, T.10
Kai, H.11
-
21
-
-
0036115199
-
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells
-
Egan M.E., Glockner-Pagel J., Ambrose C., Cahill P.A., Pappoe L., Balamuth N., Cho E., Canny S., Wagner C.A., Geibel J., and Caplan M.J. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat. Med. 8 (2002) 485-492
-
(2002)
Nat. Med.
, vol.8
, pp. 485-492
-
-
Egan, M.E.1
Glockner-Pagel, J.2
Ambrose, C.3
Cahill, P.A.4
Pappoe, L.5
Balamuth, N.6
Cho, E.7
Canny, S.8
Wagner, C.A.9
Geibel, J.10
Caplan, M.J.11
-
23
-
-
0030939425
-
The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B
-
Bierhaus A., Zhang Y., Quehenberger P., Luther T., Haase M., Muller M., Mackman N., Ziegler R., and Nawroth P.P. The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B. Thromb. Haemost. 77 (1997) 772-782
-
(1997)
Thromb. Haemost.
, vol.77
, pp. 772-782
-
-
Bierhaus, A.1
Zhang, Y.2
Quehenberger, P.3
Luther, T.4
Haase, M.5
Muller, M.6
Mackman, N.7
Ziegler, R.8
Nawroth, P.P.9
-
24
-
-
4644242039
-
Some like it hot: curcumin and CFTR
-
Davis P.B., and Drumm M.L. Some like it hot: curcumin and CFTR. Trends Mol. Med. 10 (2004) 473-475
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 473-475
-
-
Davis, P.B.1
Drumm, M.L.2
-
25
-
-
0029124018
-
A labile hyperphosphorylated c-Fos protein is induced in mouse fibroblast cells treated with a combination of phorbol ester and anti-tumor promoter curcumin
-
Huang T.S., Kuo M.L., Lin J.K., and Hsieh J.S. A labile hyperphosphorylated c-Fos protein is induced in mouse fibroblast cells treated with a combination of phorbol ester and anti-tumor promoter curcumin. Cancer Lett. 96 (1995) 1-7
-
(1995)
Cancer Lett.
, vol.96
, pp. 1-7
-
-
Huang, T.S.1
Kuo, M.L.2
Lin, J.K.3
Hsieh, J.S.4
-
28
-
-
2542480784
-
Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator
-
Gentzsch M., Chang X.B., Cui L., Wu Y., Ozols V.V., Choudhury A., Pagano R.E., and Riordan J.R. Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. Mol. Biol. Cell 15 (2004) 2684-2696
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2684-2696
-
-
Gentzsch, M.1
Chang, X.B.2
Cui, L.3
Wu, Y.4
Ozols, V.V.5
Choudhury, A.6
Pagano, R.E.7
Riordan, J.R.8
-
29
-
-
0035013543
-
The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells
-
Heda G.D., Tanwani M., and Marino C.R. The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells. Am. J. Physiol. Cell. Physiol. 280 (2001) C166-C174
-
(2001)
Am. J. Physiol. Cell. Physiol.
, vol.280
-
-
Heda, G.D.1
Tanwani, M.2
Marino, C.R.3
|