Modulation of endotoxin-induced neutrophil transendothelial migration by alveolar epithelium in a defined bilayer model

Experimental Lung Research

Volumn 32, Issue 10, 2006, Pages 455-482

  Weppler, Amy ^a   Rowter, Derek ^a   Hermanns, Iris ^b   Kirkpatrick, C James ^b   Issekutz, Andrew C ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alveolus; Coculture; Endothelium; Epithelial cell; Leukocyte; Lipopolysaccharide; Lung; Migration

Indexed keywords

ENDOTOXIN; LIPOPOLYSACCHARIDE;

ARTICLE; BILAYER MEMBRANE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL SPECIFICITY; CELL STIMULATION; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC RESISTANCE; FILTER; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LYMPHOCYTE MIGRATION; MEMBRANE FORMATION; MEMBRANE STABILIZATION; MICROSCOPY; MONOLAYER CULTURE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; UMBILICAL VEIN;

CELL LINE; CELL MOVEMENT; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LIPOPOLYSACCHARIDES; MICROPORE FILTERS; NEUTROPHILS; PULMONARY ALVEOLI;

EID: 33845756655     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140601059463     Document Type: Article

References (42)

1. Burns AR, Smith CW, Walker DC: Unique structural features that influence neutrophil emigration into the lung. Physiol Rev. 2003;83:309-336.
2. Crapo JD, Barry BE, Gehr P, Bachofen M, Weibel ER: Cell number and cell characteristics of the normal human lung. Am Rev Respir Dis. 1982;126:332-337.
3. Fehrenbach H: Alveolar epithelial type II cell: defender of the alveolus revisited. Respir Res. 2001;2:33-46.
4. Koyama S, Sato E, Nomura H, Kubo K, Miura M, Yamashita T, Nagai S, Izumi T: Monocyte chemotactic factors released from type II pneumocyte-like cells in response to TNF-alpha and IL-1alpha. Eur Respir J. 1999;13:820-828.
5. Hogg JC, Doerschuk CM: Leukocyte traffic in the lung. Annu Rev Physiol. 1995;57:97-114.
6. Doerschuk CM, Winn RK, Coxson HO, Harlan JM: CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J Immunol. 1990;144:2327-2333.
7. Hellewell PG, Young SK, Henson PM, Worthen GS: Disparate role of the beta 2-integrin CD18 in the local accumulation of neutrophils in pulmonary and cutaneous inflammation in the rabbit. Am J Respir Cell Mol Biol. 1994;10:391-398.
8. Hermanns MI, Unger RE, Kehe K, Peters K, Kirkpatrick CJ: Lung epithelial cell lines in coculture with human pulmonary microvascular endothelial cells: development of an alveolo-capillary barrier in vitro. Lab Invest. 2004;84:736-752.
9. Gueven N, Glatthaar B, Manke HG, Haemmerle H: Co-cultivation of rat pneumocytes and bovine endothelial cells on a liquid-air interface. Eur Respir J. 1996;9:968-975.
10. Casale TB, Carolan EJ: Cytokine-induced sequential migration of neutrophils through endothelium and epithelium. Inflamm Res. 1999;48:22-27.
11. Mul FP, Zuurbier AE, Janssen H, Calafat J, van Wetering S, Hiemstra PS, Roos D, Hordijk PL: Sequential migration of neutrophils across monolayers of endothelial and epithelial cells. J Leukoc Biol. 2000;68:529-537.
12. Casale TB, Mower DA, Carolan EJ: The sequential migration of neutrophils through endothelium and epithelium: a new model system. Exp Lung Res. 1998;24:709-719.
13. Hu M, Lin X, Du Q, Miller EJ, Wang P, Simms HH: Regulation of polymorphonuclear leukocyte apoptosis: role of lung endothelium-epithelium bilayer transmigration. Am J Physiol Lung Cell Mol Physiol. 2005;288:L266-L274.
14. Rannels SR, Yarnell JA, Fisher CS, Fabisiak JP, Rannels DE: Role of laminin in maintenance of type II pneumocyte morphology and function. Am J Physiol Cell Physiol. 1987;253:C835-C845.
15. Rylander R: Endotoxin and occupational airway disease. Curr Opin Allergy Clin Immunol. 2006;6:62-66.
16. Issekutz AC, Lopes N: Endotoxin activation of endothelium for polymorphonuclear leucocyte transendothelial migration and modulation by interferon-gamma. Immunology. 1993;79:600-607.
17. Drake WT, Issekutz AC: A role for alpha-thrombin in polymorphonuclear leukocyte recruitment during inflammation. Semin Thromb Hemost. 1992;18:333-340.
18. Godfrey RW: Human airway epithelial tight junctions. Microsc Res Tech. 1997;38:488-499.
19. Burke-Gaffney A, Keenan AK: Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 alpha/beta, tumor necrosis factor-alpha and interferon-gamma. Immunopharmacology. 1993;25:1-9.
20. Jagielo PJ, Thorne PS, Kern JA, Quinn TJ, Schwartz DA: Role of endotoxin in grain dust-induced lung inflammation in mice. Am J Physiol. 1996;270:L1052-L1059.
21. Jagielo PJ, Thorne PS, Watt JL, Frees KL, Quinn TJ, Schwartz DA: Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects. Chest. 1996;110:263-270.
22. Simons RK, Maier RV, Chi EY: Pulmonary effects of continuous endotoxin infusion in the rat. Circ Shock. 1991;33:233-243.
23. Lopez A, Yong S: Injury versus inflammatory response in the lungs of rats intratracheally inoculated with bacterial lipopolysaccharide. Am J Vet Res. 1986;47:1287-1292.
24. Ulich TR, Watson LR, Yin SM, Guo KZ, Wang P, Thang H, del Castillo J: The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate. Am J Pathol. 1991;138:1485-1496.
25. Ulich TR, Yin SM, Guo KZ, del Castillo J, Eisenberg SP, Thompson RC: The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation. Am J Pathol. 1991;138:521-524.
26. Mackarel AJ, Cottell DC, Fitzgerald MX, O'Connor CM: Human endothelial cells cultured on microporous filters used for leukocyte transmigration studies form monolayers on both sides of the filter. In Vitro Cell Dev Biol Anim. 1999;35:346-351.
27. Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Lehr CM: Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C. Cell Tissue Res. 2003;311:31-45.
28. Elbert KJ, Schafer UF, Schafers HJ, Kim KJ, Lee VH, Lehr CM: Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies. Pharm Res. 1999;16:601-608.
29. Boitano S, Isakson BE, Lubman RL: Culturing alveolar type I, alveolar type II, and mixed cell populations by altering the extracellular matrix promotes changes in intercellular signaling mechanisms. Chest. 2002;121:35S-36S.
30. Isakson BE, Lubman RL, Seedorf GJ, Boitano S: Modulation of pulmonary alveolar type II cell phenotype and communication by extracellular matrix and KGF. Am J Physiol Cell Physiol. 2001;281:C1291-C1299.
31. Lieber M, Smith B, Szakal A, Nelson-Rees W, Todaro G: A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer. 1976;17:62-70.
32. Balis JU, Bumgarner SD, Paciga JE, Paterson JF, Shelley SA: Synthesis of lung surfactant-associated glycoproteins by A549 cells: description of an in vitro model for human type II cell dysfunction. Exp Lung Res. 1984;6:197-213.
33. Nardone LL, Andrews SB: Cell line A549 as a model of the type II pneumocyte. Phospholipid biosynthesis from native and organometallic precursors. Biochim Biophys Acta. 1979;573:276-295.
34. Shapiro DL, Nardone LL, Rooney SA, Motoyama EK, Munoz JL: Phospholipid biosynthesis and secretion by a cell line (A549) which resembles type II aleveolar epithelial cells. Biochim Biophys Acta. 1978;530:197-207.
35. Pechkovsky DV, Zissel G, Ziegenhagen MW, Einhaus M, Taube C, Rabe KF, Magnussen H, Papadopoulos T, Schlaak M, Muller-Quernheim J: Effect of proinflammatory cytokines on interleukin-8 mRNA expression and protein production by isolated human alveolar epithelial cells type II in primary culture. Eur Cytokine Netw. 2000;11:618-625.
36. Pechkovsky DV, Zissel G, Goldmann T, Einhaus M, Taube C, Magnussen H, Schlaak M, Muller-Quernheim J: Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II. Am J Physiol Lung Cell Mol Physiol. 2002;282:L684-692.
37. Pechkovsky DV, Goldmann T, Ludwig C, Prasse A, Vollmer E, Muller-Quernheim J, Zissel G: CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II. Respir Res. 2005;6:75.
38. Carolan EJ, Casale TB: Neutrophil transepithelial migration is dependent upon epithelial characteristics. Am J Respir Cell Mol Biol. 1996;15:224-231.
39. Wan H, Winton H, Soeller C, Stewart G, Thompson P, Gruenert D, Cannell M, Garrod D, Robinson C: Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-. Eur Respir J. 2000;15:1058-1068.
40. Ulich TR, Yin S, Guo K, Yi ES, Remick D, del Castillo J: Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation. Am J Pathol. 1991;138:1097-1101.
41. Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B: Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. Crit Care Med. 2005;33:2317-2322.
42. Deleuze V, Lefort J, Bureau MF, Scherman D, Vargaftig BB: LPS-induced bronchial hyperreactivity: interference by mIL-10 differs according to site of delivery. Am J Physiol Lung Cell Mol Physiol. 2004;286:L98-L105.