Cyclosporine A inhibits IL-15-induced IL-17 production in CD4+ T cells via down-regulation of PI3K/Akt and NF-κB

Immunology Letters

Volumn 108, Issue 1, 2007, Pages 88-96

  Cho, Mi La ^a   Ju, Ji Hyeon ^a   Kim, Kyoung Woon ^a   Moon, Young Mee ^a   Lee, Seon Yeong ^a   Min, So Youn ^a   Cho, Young Gyu ^a   Kim, Hyun Sook ^a   Park, Kyung Su ^a   Yoon, Chong Hyeon ^a   Lee, Sang Heon ^b   Park, Sung Hwan ^a   Kim, Ho Youn ^a  

^a The Catholic University of Korea   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

Author keywords

CD4+ T cells; Cyclosporine A; IL 15; IL 17; NF B; PI3K; Rheumatoid arthritis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLOSPORIN A; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 15; INTERLEUKIN 17; MESSENGER RNA; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT INTERLEUKIN 15; TACROLIMUS;

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOPHARMACOLOGY; MALE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; AGED; ARTHRITIS, RHEUMATOID; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-15; INTERLEUKIN-17; MALE; MIDDLE AGED; MODELS, IMMUNOLOGICAL; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER;

EID: 33845744729     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2006.11.001     Document Type: Article

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