Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations

Xenobiotica

Volumn 37, Issue 1, 2007, Pages 103-112

  Chen, Y ^a   Li, G ^b   Yin, S ^b   Xu, J ^b   Ji, Z ^b   Xiu, X ^c   Liu, L ^d   Ma, D ^e  

^a XINJIANG MEDICAL UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c Hospitals of Prevention and Treatment for Occupational Diseases in Zhengzhou   (China)

^d Hospitals of Prevention and Treatment for Occupational Diseases in Kaifeng   (China)

^e Hospitals of Prevention and Treatment for Occupational Diseases in Tianjin   (China)

Author keywords

Benzene occupational exposure; Benzene risk assessment; Benzene toxicity; Biomarkers of benzene exposure; Genetic polymorphisms

Indexed keywords

BENZENE; CYTOCHROME P450 2E1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; MYELOPEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ADULT; AGED; ARTICLE; BENZENE INTOXICATION; CHINESE; CONTROLLED STUDY; DRUG DETOXIFICATION; ENZYME METABOLISM; FEMALE; GENE ACTIVITY; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTOXICATION; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE; WORK ENVIRONMENT;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BENZENE; CASE-CONTROL STUDIES; CHINA; CYTOCHROME P-450 CYP2E1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); OCCUPATIONAL EXPOSURE; OXIDOREDUCTASES; PEROXIDASE; PHARMACOGENETICS; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 33845742435     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250601001662     Document Type: Article

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