Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)-expressing colon cancer using genetically modified dendritic cells that express CEA and T helper-type 1 cytokines in CEA transgenic mice

International Journal of Cancer

Volumn 120, Issue 3, 2007, Pages 585-593

  Ojima, Toshiyasu ^a   Iwahashi, Makoto ^a   Nakamura, Masaki ^a   Matsuda, Kenji ^a   Nakamori, Mikihito ^a   Ueda, Kentaro ^a   Naka, Teiji ^a   Ishida, Koichiro ^a   James Primus, F ^b   Yamaue, Hiroki ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adenoviral vector; CEA transgenic mice; Dendritic cells; GM CSF; IL 12

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOIMMUNITY; CANCER IMMUNIZATION; CD8+ T LYMPHOCYTE; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; DNA MODIFICATION; FEMALE; GENETIC TRANSDUCTION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD86; CANCER VACCINES; CARCINOEMBRYONIC ANTIGEN; CELL LINE; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNOTHERAPY, ADOPTIVE; INTERLEUKIN-12; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; RECEPTORS, CHEMOKINE; SPLEEN; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TIME FACTORS; TRANSFECTION;

EID: 33845711011     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22298     Document Type: Article

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