Brazilian green propolis protects against retinal damage in vitro and in vivo

Evidence-based Complementary and Alternative Medicine

Volumn 3, Issue 1, 2006, Pages 71-77

  Inokuchi, Yuta ^a   Shimazawa, Masamitsu ^a   Nakajima, Yoshimi ^a,c   Suemori, Shinsuke ^a,b   Mishima, Satoshi ^c   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c Api Company Ltd   (Japan)

Author keywords

Apoptosis; Lipid peroxidation; NMDA; Retinal damage; Retinal ganglion cell

Indexed keywords

3,4 DI O CAFFEOYLQUINIC ACID; 3,5 DI O CAFFEOYLQUINIC ACID; 4,5 DI O CAFFEOYLQUINIC ACID; ALPHA TOCOPHEROL; ARTEPILLIN C; BACCHARIN; CHLOROGENIC ACID; DRUPANIN; DYE; HOE 33342; HYDROGEN PEROXIDE; ISOSAKURANETIN; N METHYL DEXTRO ASPARTIC ACID; PARA COUMARIC ACID; PROPOLIS; RESAZURIN; STAUROSPORINE; TROLOX C; UNCLASSIFIED DRUG; YO PRO 1;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACCHARIS DRACUNCULIFOLIA; CELL VIABILITY; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REDUCTION; RETINA; RETINA INJURY; RETINA INNER PLEXIFORM LAYER;

EID: 33745712833     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nek005     Document Type: Article

References (38)

1. Bonne C, Muller A, Villain M. Free radicals in retinal ischemia. Gen Pharmacol 1998;30:275-80.
2. Dreyer EB. A proposed role for excitotoxicity in glaucoma. J Glaucoma 1998;7:62-7.
3. Neufeld AH. Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol 1999;43:S129-35.
4. McKinnon SJ. Glaucoma, apoptosis, and neuroprotection. Curr Opin Ophthalmol 1997;8:28-37.
5. Clark AF, Yorio T. Ophthalmic drug discovery. Nat Rev Drug Discov 2003;2:448-59.
6. Aga H, Shibuya T, Sugimoto T, Kurimoto M, Nakajima SH. Isolation and identification of antimicrobial compounds in Brazilian propolis. Biosci Biotechnol Biochem 1994;58:945-6.
7. Marcucci MC, De Camargo FA, Lopes CMA. Identification of amino acids in Brazilian propolis. Z Naturforsch [C] 1996;51:11-4.
8. Bankova V, Marcucci MC, Simova S, Nikolova N, Kujumgiev A. Anti-bacterial diterpenic acids from Brazilian propolis. Z Naturforsch [C] 1996;51:277-80.
9. Drago B, Mombelli B, Vecchi EDE, Fassina MC, Tocalli L, Gismondo MR. In vitro antimicrobial activity of propolis dry extract. J Chemother 2000;12:390-5.
10. Mizoeva OK, Calder PC. The effect of propolis and its components on eicosanoid production during the inflammatory response. Prostaglandins Leukot Essent Fatty Acids 1996;55:441-9.
11. Krol W, Czuba Z, Scheller S, Gabrys J, Grabiec S, Shani J. Anti-oxidant property of ethanolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminol. Biochem Int 1990;21:593-7.
12. Scheller S, Wilczok T, Imielski S, Krol W, Gabrys J, Shani J. Free radical scavenging by ethanol extract of propolis. Int J Radiat Biol 1990;57:461-5.
13. Chen CN, Weng MS, Wu CL, Lin JK. Comparison of radical scavenging activity, cytotoxic effects and apoptosis induction in human melanoma cells by Taiwanese propolis from different sources. Evid Based Complement Alternat Med 2004;1:175-85.
14. Matsuno T. Isolation and characterization of the tumoricidal substance from Brazilian propolis. Honeybee Sci 1992;13:49-54.
15. Kumazawa S, Yoneda M, Shibata I, Kanaeda J, Hamasaka T, Nakayama T. Direct evidence for the plant origin of Brazilian propolis by the observation of honeybee behavior and phytochemical analysis. Chem Pharm Bull 2003;51:740-2.
16. Kumazawa S, Yoneda M, Nakayama T. Constituents in Brazilian propolis and its plant of origin. FFI J 2004;209:132-9.
17. Midorikawa K, Banskota AH, Tezuka Y, Nagaoka T, Matsushige K, Message D, et al. Liquid chromatography-mass spectrometry analysis of propolis. Phytochem Anal 2001;12:366-73.
18. Park YK, Alencar SM, Aguiar CL. Botanical origin and chemical composition of Brazilian propolis. J Agric Food Chem 2002;50:2502-6.
19. Teixeira EW, Negri G, Meira RM, Message D, Slatino A. Plant origin of green propolis: bee behavior, plant anatomy and chemistry. Evid Based Complement Alternat Med 2005;2:85-92.
20. Simoes LM, Gregorio LE, Da Silva Filho AA, de Souza ML, Azzolini AE, Bastos JK, et al. Effect of Brazilian green propolis on the production of reactive oxygen species by stimulated neutrophils. J Ethnopharmacol 2004;94:59-65.
21. Marcucci MC, Ferreres F, Garcia-Viguera C, Bankova VS, De Castro SL, Dantas AP, et al. Phenolic compounds from Brazilian propolis with pharmacological activities. J Ethnopharmacol 2001;74:105-12.
22. Shimazawa M, Chikamatsu S, Morimoto N, Mishima S, Nagai H, Hara H. Neuroprotection by Brazilian green propolis against in vitro and in vivo ischemic neuronal damage. Evid Based Complement Alternat Med 2005;2:201-7.
23. Shimazawa M, Yamashima T, Agarwal N, Hara H. Neuroprotective effects of minocycline against in vitro and in vivo retinal cell damage. Brain Res 2005;1053:185-94.
24. Tam BB, Siu AW, Lam AF, Lee EY. Effects of vitamin E and pinoline on retinal lipid peroxidation. Clin Exp Optom 2004;87:171-4.
25. Yoneda S, Tanihara H, Kido N, Honda Y, Goto W, Hara H, et al. Interleukin-1β mediates ischemic injury in the rat retina. Exp Eye Res 2001;73:661-7.
26. Chan PH, Schmidley JM, Fishman RA, Longar SM. Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals. Neurology 1984;34:315-20.
27. Hara H, Sukamoto T, Kogure K. Mechanism and pathogenesis of ischemia-induced neuronal damage. Prog Neurobiol 1993;40:645-70.
28. Siesjo BK. Cell damage in the brain: a speculative synthesis. J Cereb Blood Flow Metabol 1981;1:155-84.
29. Ferreira SM, Lerner SF, Brunzini R, Evelson PA, Llesuy SF. Oxidative stress markers in aqueous humor of glaucoma. Am J Ophthalmol 2004;137:62-9.
30. Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J 1991;10:2247-58.
31. Lo YY, Cruz TF. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J Biol Chem 1995;270:11727-30.
32. Murrell GA, Francis MJ, Bromley L. Modulation of fibroblast proliferation by oxygen free radicals. Biochem J 1990;265:659-65.
33. Wolfe JT, Ross D, Cohen GM. A role for metals and free radicals in the induction of apoptosis in thymocytes. FEBS Lett 1994;352:58-62.
34. 2. Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase. J Biol Chem 2001;276:46379-85.
35. Kitamura Y, Ota T, Matsuoka Y, Tooyama I, Kimura H, Shimohama S, et al. Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells. Glia 1999;25:154-64.
36. - channel. Proc Natl Acad Sci USA 2004;101:6770-3.
37. Ichikawa H, Satoh K, Tobe T, Yasuda I, Ushio F, Matsumoto K, et al. Free radical scavenging activity of propolis. Redox Rep 2002;7:347-50.
38. Mishima S, Narita Y, Chikamatsu S, Inoh Y, Ohta S, Yoshida C, et al. Effects of propolis on cell growth and gene expression in HL-60 cells. J Ethnopharmacol 2005;99:5-11.