ABSENCE OF SIDE EFFECTS;
ADULT;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD SAMPLING;
DRUG ABSORPTION;
DRUG BLOOD LEVEL;
DRUG DISTRIBUTION;
DRUG ELIMINATION;
DRUG HALF LIFE;
DRUG METABOLISM;
ETHNIC DIFFERENCE;
GENETIC POLYMORPHISM;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN EXPERIMENT;
LABORATORY TEST;
LIVER TOXICITY;
MALE;
NORMAL HUMAN;
SINGLE DRUG DOSE;
ULTRAVIOLET RADIATION;
ADMINISTRATION, ORAL;
ADULT;
AREA UNDER CURVE;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
HUMANS;
HYPOGLYCEMIC AGENTS;
MALE;
THAILAND;
THIAZOLIDINEDIONES;
Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: Clinical relevance
Kirchheiner J, Roots I, Goldammer M, Rosenkranz B, Brockmoller J. Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. Clin Pharmacokinet 2005; 44: 1209-25.
U.S. Department of Health and Human Services Center for Drug Evaluation and Research (CDER) Center for Veterinary Medicine (CVM). May Available from: Accessed 26 Oct, 2006
U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Veterinary Medicine (CVM). Guidance for industry: bioanalytical method validation. May 2001. Available from: http://www.fda.gov/CDER/GUIDANCE/4252fnl.htm Accessed 26 Oct, 2006
Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone
Jaakkola T, Backman JT, Neuvonen M, Neuvonen PJ. Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone. Clin Pharmacol Ther 2005; 77: 404-14.
Studies on the metabolism of the new antidiabetic agent pioglitazone. Identification of metabolites in rats and dogs
Kiyota Y, Kondo T, Maeshiba Y, Hashimoto A, Yamashita K, Yoshimura Y, et al. Studies on the metabolism of the new antidiabetic agent pioglitazone. Identification of metabolites in rats and dogs. Arzneimittelforschung 1997; 47: 22-8.