Studies on the metabolism of the new antidiabetic agent pioglitazone. Identification of metabolites in rats and dogs

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 1, 1997, Pages 22-28

  Kiyota, Yutaka ^a   Kondo, Takahiro ^a   Maeshiba, Yoshihiro ^a   Hashimoto, Ai ^a   Yamashita, Kenji ^a   Yoshimura, Yoshinobu ^a   Motohashi, Michio ^a   Tanayama, Shigeharu ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

AD 4833, metabolites; antidiabetic agents; CAS 105355 27 9; pioglitazone

Indexed keywords

ANTIDIABETIC AGENT; CARBON 14; DRUG METABOLITE; PIOGLITAZONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ORAL DRUG ADMINISTRATION; RAT;

ADMINISTRATION, ORAL; ANIMALS; BILE; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; DOGS; HYPOGLYCEMIC AGENTS; INTUBATION, GASTROINTESTINAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLES; THIAZOLIDINEDIONES;

EID: 0031052587     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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