The developing cardiac myocyte: Maturation of excitability and excitation-contraction coupling

Annals of the New York Academy of Sciences

Volumn 1080, Issue , 2006, Pages 63-75

  Schroder, Elizabeth A ^a   Wei, Yidong ^a   Satin, Jonathan ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Calcium channel; Cardiac electrophysiology; Heart development; Ion channel; Voltage gated ion channel

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL T TYPE;

ANIMAL CELL; CALCIUM CURRENT; CELL FUNCTION; CELL MATURATION; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EXCITATION CONTRACTION COUPLING; FETUS DEVELOPMENT; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART MUSCLE EXCITABILITY; MOLECULAR MECHANICS; MOUSE; NONHUMAN;

EID: 33845659497     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1380.006     Document Type: Conference Paper

References (28)

1. BERS, D.M. 2001. Excitation-Contraction Coupling and Cardiac Contractile Force, 2nd ed. Kluwer Academic Publishers. Dordrecht.
2. 2+ window current. Circ. Res. 70: 456-464.
3. VORNANEN, M., N. SHEPHERD & G. ISENBERG. 1994. Tension-voltage relations of single myocytes reflect Ca release triggered by Na/Ca exchange at 35 degrees C but not 23 degrees C. Am. J. Physiol. 267: C623-C632.
4. KLITZNER, T.S. & W.F. FRIEDMAN. 1989. A diminished role for the sarcoplasmic reticulum in newborn myocardial contraction: effects of ryanodine. Pediatr. Res. 26: 98-101.
5. TAKESHIMA, H., S. KOMAZAKI, et al. 1998. Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J. 17: 3309-3316.
6. SEISENBERGER, C., V. SPECHT, et al. 2000. Functional embryonic cardiomyocytes after disruption of the L-type α1C (Cav1.2) calcium channel gene in the mouse. J. Biol. Chem. 275: 39193-39199.
7. XU, M., A. WELLING, S. PAPARISTO, et al. 2003. Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice. J. Biol. Chem. 278: 40837-40841.
8. CRIBBS, L.L., B.L. MARTIN, E.A. SCHRODER, et al. 2001. Identification of the T-type calcium channel (CaV3.1d) in developing mouse heart. Circ. Res. 88: 403-407.
9. SATIN, J. & L.L. CRIBBS. 2000. Identification of a T-type calcium channel isoform in murine atrial myocytes (AT-1). Circ. Res. 86: 636-642.
10. SATIN, J. & L.A. BURNS. 2001. Steady-state calcium flux through T-type calcium channels require active Ca-calmodulin kinase. Circulation 104: II-251.
11. 2+ oscillations drive spontaneous contractions in cardiomyocytes during early development. Proc. Natl. Acad. Sci. USA 96: 8259-8264.
12. KOLOSSOV, E., B.K. FLEISCHMANN, Q. LIU, et al. 1998. Functional characteristics of ES cell-derived cardiac precursor cells identified by tissue-specific expression of the green fluorescent protein. J. Cell Biol. 143: 2045-2056.
13. SATIN, J., I. KEHAT, O. CASPI, et al. 2004. Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes. J. Physiol. 559: 479-496.
14. SAUER, H., T. THEBEN, J. HESCHELER, et al. 2001. Characteristics of calcium sparks in cardiomyocytes derived from embryonic stem cells. Am. J. Physiol. Heart Circ. Physiol. 281: H411-H421.
15. 2+ oscillations in cardiac cells. J. Cell Biol. 152: 717-728.
16. LEE, J.-H., J.C. GOMORA, L.L. CRIBBS & E. PEREZ-REYES. 1999. Nickel block of three cloned T-type calcium channels: low concentrations selectively block α1H. Biophys. J. 77: 3034-3042.
17. ZAMPONI, G.W., E. BOURINET & T.P. SNUTCH. 1996. Nickel block of a family of neuronal calcium channels: subtype and subunit-dependent action at multiple sites. J. Membr. Biol. 151: 77-90.
18. GYSEMBERGH, A., S. LEMAIRE, et al. 1999. Pharmacological manipulation of Ins(1,4,5)P3 signaling mimics preconditioning in rabbit heart. Am. J. Physiol. Heart Circ. Physiol. 277: H2458-H2469.
19. 2+ signalling and the generation of arrhythmias in rat atrial myocytes. J. Physiol. (Lond.) 541: 395-409.
20. PEPPIATT, C.M., T.J. COLLINS, et al. 2003. 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels. Cell Calcium 34: 97-108.
21. 2+ stores in permeabilized A7r5 cells. Cell Calcium 29: 111-116.
22. 2+ release. J. Biochem. (Tokyo) 122: 498-505.
23. 2+ release. FASEB J. 16: 1145-1150.
24. 2+ handling in mouse ventricular cells from early embryo to adulthood. Life Sci. 71: 1279-1292.
25. 2+ channels in embryonic mouse heart. Circ. Res. 78: 371-378.
26. DAVIES, M.P., R.H. AN, et al. 1996. Developmental changes in ionic channel activity in the embryonic murine heart. Circ. Res. 78: 15-25.
27. V1.3 L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J. Neurosci. 21: 5944-5951.
28. FIJNVANDRAAT, A.C., A.C. VAN GINNEKEN, et al. 2003. Cardiomyocytes derived from embryonic stem cells resemble cardiomyocytes of the embryonic heart tube. Cardiovasc. Res. 58: 399-409.