메뉴 건너뛰기




Volumn 10, Issue 18 I, 2004, Pages 6006-6012

Effects of Gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEFITINIB;

EID: 4644285519     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0770     Document Type: Article
Times cited : (44)

References (34)
  • 1
    • 0034068319 scopus 로고    scopus 로고
    • Antitumour effect and potentiation of cytotoxic drug activity in human cancer cells by GEFTTINIB (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
    • Ciardiello F, Caputo R, Bianco R, et al. Antitumour effect and potentiation of cytotoxic drug activity in human cancer cells by GEFTTINIB (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res 2000;6:2053-63.
    • (2000) Clin Cancer Res , vol.6 , pp. 2053-2063
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3
  • 2
    • 0037109014 scopus 로고    scopus 로고
    • ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
    • Wakeling AE, Guy SP, Woodburn JR, et al. ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 2002;62:5749-54.
    • (2002) Cancer Res , vol.62 , pp. 5749-5754
    • Wakeling, A.E.1    Guy, S.P.2    Woodburn, J.R.3
  • 3
    • 0036842170 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
    • Baselga J, Rischin D, Ranson M, et al. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J Clin Oncol 2002;20:4292-302.
    • (2002) J Clin Oncol , vol.20 , pp. 4292-4302
    • Baselga, J.1    Rischin, D.2    Ranson, M.3
  • 4
    • 0033063774 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its inhibition in cancer therapy
    • Woodburn JR. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol Ther 1999;82:241-50.
    • (1999) Pharmacol Ther , vol.82 , pp. 241-250
    • Woodburn, J.R.1
  • 5
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. Final results from a phase II trial of ZD 1839 (Iressa) for patients with advanced non-small cell lung cancer (IDEAL 1)
    • Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. Final results from a phase II trial of ZD 1839 (Iressa) for patients with advanced non-small cell lung cancer (IDEAL 1). J Clin Oncol 2003;21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 6
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. J Am Med Assoc 2003;290:2149-58.
    • (2003) J Am Med Assoc , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 7
    • 0037106273 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor for cancer therapy
    • Mendelsohn J. Targeting the epidermal growth factor receptor for cancer therapy. J Clin Oncol 2002;20:1S-13S.
    • (2002) J Clin Oncol , vol.20
    • Mendelsohn, J.1
  • 8
    • 0033605560 scopus 로고    scopus 로고
    • ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
    • Worthylake R, Opresko LK, Wiley HS. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J Biol Chem 1999;274:8865-74.
    • (1999) J Biol Chem , vol.274 , pp. 8865-8874
    • Worthylake, R.1    Opresko, L.K.2    Wiley, H.S.3
  • 9
    • 0035476803 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor Gefitinib ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
    • Moasser MM, Basso A, Averbuch SD, Rosen N. The tyrosine kinase inhibitor Gefitinib ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res 2001;61:7184-88.
    • (2001) Cancer Res , vol.61 , pp. 7184-7188
    • Moasser, M.M.1    Basso, A.2    Averbuch, S.D.3    Rosen, N.4
  • 10
    • 0000329007 scopus 로고    scopus 로고
    • A phase II trial of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor OSI-774, following platinum-based chemotherapy, in patients with advanced EGFR-expressing, non-small cell lung cancer (NSCLC)
    • Perez-Soler R, Chachoua A, Huberman M, et al. A phase II trial of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor OSI-774, following platinum-based chemotherapy, in patients with advanced EGFR-expressing, non-small cell lung cancer (NSCLC). Proc Am Clin Oncol 2001;20:310a.
    • (2001) Proc Am Clin Oncol , vol.20
    • Perez-Soler, R.1    Chachoua, A.2    Huberman, M.3
  • 11
    • 0043132288 scopus 로고    scopus 로고
    • Gefitinib in pretreated non-small cell lung cancer (NSCLC): Analysis of efficacy and correlation with HER2 and epidermal growth factor receptor expression in locally advanced or metastatic NSCLC
    • Cappuzzo F, Gregore V, Rossi E, et al. Gefitinib in pretreated non-small cell lung cancer (NSCLC): analysis of efficacy and correlation with HER2 and epidermal growth factor receptor expression in locally advanced or metastatic NSCLC. J Clin Oncol 2003;21:2658-63.
    • (2003) J Clin Oncol , vol.21 , pp. 2658-2663
    • Cappuzzo, F.1    Gregore, V.2    Rossi, E.3
  • 12
    • 0021399556 scopus 로고
    • Biosynthesis of the epidermal growth factor receptor in A431 cells
    • Mayes EL, Waterfield MD. Biosynthesis of the epidermal growth factor receptor in A431 cells. EMBO J 1984;3:531-7.
    • (1984) EMBO J , vol.3 , pp. 531-537
    • Mayes, E.L.1    Waterfield, M.D.2
  • 13
    • 0026071364 scopus 로고
    • The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3
    • Zabrecky JR, Lam T, McKenzie SJ, Carney W. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J Biol Chem 1991;266:1716-20.
    • (1991) J Biol Chem , vol.266 , pp. 1716-1720
    • Zabrecky, J.R.1    Lam, T.2    McKenzie, S.J.3    Carney, W.4
  • 14
    • 0027390140 scopus 로고
    • Detection of the extracellular domain of c-erbB-2 oncoprotein in sera from patients with various carcinomas: Correlation with tumor markers
    • Wu JT, Astill ME, Zhang P. Detection of the extracellular domain of c-erbB-2 oncoprotein in sera from patients with various carcinomas: correlation with tumor markers. J Clin Lab Anals 1993;7:31-40.
    • (1993) J Clin Lab Anals , vol.7 , pp. 31-40
    • Wu, J.T.1    Astill, M.E.2    Zhang, P.3
  • 15
    • 0029049759 scopus 로고
    • Serum level and tissue expression of c-erbB-2 protein in lung adenocarcinoma
    • Osaki T, Mitsudomi T, Oyama T, Nakanishi R, Yasumoto K. Serum level and tissue expression of c-erbB-2 protein in lung adenocarcinoma. Chest 1995;108:157-62.
    • (1995) Chest , vol.108 , pp. 157-162
    • Osaki, T.1    Mitsudomi, T.2    Oyama, T.3    Nakanishi, R.4    Yasumoto, K.5
  • 16
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. J Nat Cancer Inst 2000;92:205-16.
    • (2000) J Nat Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 17
    • 0003575142 scopus 로고
    • National Institutes of Health, Cancer Therapy Evaluation Program, Division of Cancer Treatment, Bethesda
    • Common toxicity criteria. National Institutes of Health, Cancer Therapy Evaluation Program, Division of Cancer Treatment, Bethesda, 1993.
    • (1993) Common Toxicity Criteria
  • 18
    • 0036139727 scopus 로고    scopus 로고
    • Pharmacodynamic studies of the epidermal growth factor receptor inhibitor Gefitinib in skin from cancer patients: Histopathologic and molecular consequences of receptor inhibition
    • Albanell J, Rojo F, Averbuch S, et al. Pharmacodynamic studies of the epidermal growth factor receptor inhibitor Gefitinib in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition. J Clin Oncol 2002;20:110-24.
    • (2002) J Clin Oncol , vol.20 , pp. 110-124
    • Albanell, J.1    Rojo, F.2    Averbuch, S.3
  • 20
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 21
    • 0033392005 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
    • Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 1999;17:259-69.
    • (1999) Invest New Drugs , vol.17 , pp. 259-269
    • Huang, S.M.1    Harari, P.M.2
  • 22
    • 0038705941 scopus 로고    scopus 로고
    • Real-time fluorescent quantitative PCR reveals increased HER2, HER3, and unchanged HER1 (EGFR) mRNA expression levels in colon carcinomas
    • Calvo B, Caskey L, Earp H. Real-time fluorescent quantitative PCR reveals increased HER2, HER3, and unchanged HER1 (EGFR) mRNA expression levels in colon carcinomas. Proc 2001 Am Assoc Cancer Res Int Conf 2002;7:3761s.
    • (2002) Proc 2001 Am Assoc Cancer Res Int Conf , vol.7
    • Calvo, B.1    Caskey, L.2    Earp, H.3
  • 23
    • 0023240345 scopus 로고
    • Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin
    • Chou CK, Dull TJ, Russell DS, et al. Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J Biol Chem 1987;262:1842-7.
    • (1987) J Biol Chem , vol.262 , pp. 1842-1847
    • Chou, C.K.1    Dull, T.J.2    Russell, D.S.3
  • 24
    • 0023840804 scopus 로고
    • Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies
    • Glenney JR Jr, Chen WS, Lazar CS, et al. Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell 1988;52:675-84.
    • (1988) Cell , vol.52 , pp. 675-684
    • Glenney Jr., J.R.1    Chen, W.S.2    Lazar, C.S.3
  • 25
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: Generation and biological function
    • Rose-John S, Heinrich PC. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 1994;300:281-90.
    • (1994) Biochem J , vol.300 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 26
    • 0027524245 scopus 로고
    • The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolytic cleavage
    • Pupa SM, Menard S, Morelli D, Pozzi B, De Palo G, Colnaghi MI. The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolytic cleavage. Oncogene 1993;8:2917-23.
    • (1993) Oncogene , vol.8 , pp. 2917-2923
    • Pupa, S.M.1    Menard, S.2    Morelli, D.3    Pozzi, B.4    De Palo, G.5    Colnaghi, M.I.6
  • 27
    • 0021257637 scopus 로고
    • Expression cloning of human EGF receptor complementary DNA: Gene amplification and three related messenger RNA products in A431 cells
    • Lin CR, Chen WS, Kruiger W, et al. Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science 1984;224:843-8.
    • (1984) Science , vol.224 , pp. 843-848
    • Lin, C.R.1    Chen, W.S.2    Kruiger, W.3
  • 28
    • 0024457717 scopus 로고
    • Epidermal growth factor-induced truncation of the epidermal growth factor receptor
    • Decker SJ. Epidermal growth factor-induced truncation of the epidermal growth factor receptor. J Biol Chem 1989;264:17641-4.
    • (1989) J Biol Chem , vol.264 , pp. 17641-17644
    • Decker, S.J.1
  • 29
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of Erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • Soulieres D, Senzer NN, Yokes EE, Hidalgo M, Agarwala SS, Siu LL. Multicenter phase II study of Erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 2004;22:77-85.
    • (2004) J Clin Oncol , vol.22 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Yokes, E.E.3    Hidalgo, M.4    Agarwala, S.S.5    Siu, L.L.6
  • 30
    • 0034329630 scopus 로고    scopus 로고
    • Second-line chemotherapy in relapsing or refractory non-small-cell lung cancer: A review
    • Huisman C, Smit EF, Giaccone G, Postmus PE. Second-line chemotherapy in relapsing or refractory non-small-cell lung cancer: a review. J Clin Oncol 2000;18:3722-30.
    • (2000) J Clin Oncol , vol.18 , pp. 3722-3730
    • Huisman, C.1    Smit, E.F.2    Giaccone, G.3    Postmus, P.E.4
  • 31
    • 1842685104 scopus 로고    scopus 로고
    • Phase II study of weekly paclitaxel as second-line therapy in patients with advanced non-small cell lung cancer pretreated with cisplatin-based chemotherapy
    • Ceresoli GL, Gregorc V, Cordio S, et al. Phase II study of weekly paclitaxel as second-line therapy in patients with advanced non-small cell lung cancer pretreated with cisplatin-based chemotherapy. Lung Cancer 2004;44:231-9.
    • (2004) Lung Cancer , vol.44 , pp. 231-239
    • Ceresoli, G.L.1    Gregorc, V.2    Cordio, S.3
  • 32
    • 1542438546 scopus 로고    scopus 로고
    • Can rash associated with HER1/EGFR inhibition be used as a marker of outcome?
    • Perez-Soler R. Can rash associated with HER1/EGFR inhibition be used as a marker of outcome? Oncology 2003;17:23-8.
    • (2003) Oncology , vol.17 , pp. 23-28
    • Perez-Soler, R.1
  • 33
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of Cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ Sr, Needle MN, Kopit J, Mayer RJ. Phase II trial of Cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004;22:1201-8.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 34
    • 0037674062 scopus 로고    scopus 로고
    • Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
    • Cohen EE, Rosen F, Stadler WM, et al. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003;21:1980-7.
    • (2003) J Clin Oncol , vol.21 , pp. 1980-1987
    • Cohen, E.E.1    Rosen, F.2    Stadler, W.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.