A novel dodecapeptide from a combinatorial synthetic library exhibits potent antifungal activity and synergy with standard antimycotic agents

International Journal of Antimicrobial Agents

Volumn 29, Issue 1, 2007, Pages 73-78

  Duggineni, S ^a   Srivastava, G ^a   Kundu, B ^a   Kumar, M ^a   Chaturvedi, A K ^a   Shukla, P K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antifungal; Dodecapeptide; Synergism; Therapeutic index

Indexed keywords

AMPHOTERICIN B; ARGINYLTRYPTOPHANYLTRYPTOPHANYLARGINYL DEXTRO TRYPTOPHANYL DEXTRO PHENYLALANYLISOLEUCYL DEXTRO PHENYLALANYLHISTIDYLTRYPTOPHANYLARGINYLTRYPTOPHANAMINE; FLUCONAZOLE; FLUCYTOSINE; OLIGOPEPTIDE; PEPTIDE LIBRARY;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTICLE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SYNTHESIS; ERYTHROCYTE; HEMOLYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RABBIT;

AMINO ACID SEQUENCE; AMPHOTERICIN B; ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYPTOCOCCUS NEOFORMANS; DRUG SYNERGISM; ERYTHROCYTES; FLUCONAZOLE; FLUCYTOSINE; FUNGI; HEMOLYSIS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; OLIGOPEPTIDES; RABBITS;

EID: 33845647193     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.08.038     Document Type: Article

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