메뉴 건너뛰기




Volumn 25, Issue 6, 2007, Pages 1104-1113

Mycobacterium bovis BCG as a delivery system for the RAP-1 antigen from Babesia bovis

Author keywords

Babesia bovis; BCG; Heterologous

Indexed keywords

RECOMBINANT ANTIGEN; RHOPTRY ASSOCIATED PROTEIN 1;

EID: 33845639682     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.09.069     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0028941202 scopus 로고
    • International collaborative research: significance of tick-borne hemoparasitic diseases to world animal health
    • Uilenberg G. International collaborative research: significance of tick-borne hemoparasitic diseases to world animal health. Vet Parasitol 57 (1995) 19-41
    • (1995) Vet Parasitol , vol.57 , pp. 19-41
    • Uilenberg, G.1
  • 3
    • 0033168163 scopus 로고    scopus 로고
    • Designing blood stage vaccines against Babesia bovis and B. bigemina
    • Brown W.C., and Palmer G.H. Designing blood stage vaccines against Babesia bovis and B. bigemina. Parasitol Today 15 (1999) 275-281
    • (1999) Parasitol Today , vol.15 , pp. 275-281
    • Brown, W.C.1    Palmer, G.H.2
  • 4
    • 0035935659 scopus 로고    scopus 로고
    • Advances and prospects for subunit vaccines against protozoa of veterinary importance
    • Jenkins M.C. Advances and prospects for subunit vaccines against protozoa of veterinary importance. Vet Parasitol 101 (2001) 291-310
    • (2001) Vet Parasitol , vol.101 , pp. 291-310
    • Jenkins, M.C.1
  • 5
    • 0041823439 scopus 로고    scopus 로고
    • Stimulation of T-helper cell gamma interferon and immunoglobulin G responses specific for Babesia bovis rhoptry-associated protein 1 (RAP-1) or a RAP-1 protein lacking the carboxy-terminal repeat region is insufficient to provide protective immunity against virulent B. bovis challenge
    • Norimine J., Mosqueda J., Suarez C., Palmer G.H., McElwain T.F., Mbassa G., et al. Stimulation of T-helper cell gamma interferon and immunoglobulin G responses specific for Babesia bovis rhoptry-associated protein 1 (RAP-1) or a RAP-1 protein lacking the carboxy-terminal repeat region is insufficient to provide protective immunity against virulent B. bovis challenge. Infect Immun 71 (2003) 5021-5032
    • (2003) Infect Immun , vol.71 , pp. 5021-5032
    • Norimine, J.1    Mosqueda, J.2    Suarez, C.3    Palmer, G.H.4    McElwain, T.F.5    Mbassa, G.6
  • 6
    • 0023740058 scopus 로고
    • Identification of Babesia bovis merozoite surface antigens by using immune bovine sera and monoclonal antibodies
    • Goff W.L., Davis W.C., Palmer G.H., McElwain T.F., Johnson W.C., Bailey J.F., et al. Identification of Babesia bovis merozoite surface antigens by using immune bovine sera and monoclonal antibodies. Infect Immun 56 (1988) 2363-2368
    • (1988) Infect Immun , vol.56 , pp. 2363-2368
    • Goff, W.L.1    Davis, W.C.2    Palmer, G.H.3    McElwain, T.F.4    Johnson, W.C.5    Bailey, J.F.6
  • 7
    • 0026073311 scopus 로고
    • Characterization of the gene encoding a 60-kDa Babesia bovis merozoite protein with conserved and surface exposed epitopes
    • Suarez C.E., Palmer G.H., Jasmer D.P., Hines S.A., Perryman L.E., and McElwain T.F. Characterization of the gene encoding a 60-kDa Babesia bovis merozoite protein with conserved and surface exposed epitopes. Mol Biochem Parasitol 46 (1991) 45-52
    • (1991) Mol Biochem Parasitol , vol.46 , pp. 45-52
    • Suarez, C.E.1    Palmer, G.H.2    Jasmer, D.P.3    Hines, S.A.4    Perryman, L.E.5    McElwain, T.F.6
  • 8
    • 0032104019 scopus 로고    scopus 로고
    • Structure, sequence, and transcriptional analysis of the Babesia bovis rap-1 multigene locus
    • Suarez C.E., Palmer G.H., Hötzel I., and McElwain T.F. Structure, sequence, and transcriptional analysis of the Babesia bovis rap-1 multigene locus. Mol Biochem Parasitol 93 (1998) 215-224
    • (1998) Mol Biochem Parasitol , vol.93 , pp. 215-224
    • Suarez, C.E.1    Palmer, G.H.2    Hötzel, I.3    McElwain, T.F.4
  • 10
    • 0030016904 scopus 로고    scopus 로고
    • Babesia bovis rhoptry-associated protein 1 is immunodominant for T helper cells of immune cattle and contains T-cell epitopes conserved among geographically distant B. bovis strains
    • Brown W.C., McElwain T.F., Ruef B.J., Suarez C.E., Shkap V., Chitko-McKown C.G., et al. Babesia bovis rhoptry-associated protein 1 is immunodominant for T helper cells of immune cattle and contains T-cell epitopes conserved among geographically distant B. bovis strains. Infect Immun 64 (1996) 3341-3350
    • (1996) Infect Immun , vol.64 , pp. 3341-3350
    • Brown, W.C.1    McElwain, T.F.2    Ruef, B.J.3    Suarez, C.E.4    Shkap, V.5    Chitko-McKown, C.G.6
  • 11
    • 0024707546 scopus 로고
    • A recombinant surface protein of Babesia bovis elicits bovine antibodies that react with live merozoites
    • Reduker D.W., Jasmer D.P., Goff W.L., Perryman L.E., Davis W.C., and McGuire T.C. A recombinant surface protein of Babesia bovis elicits bovine antibodies that react with live merozoites. Mol Biochem Parasitol 35 (1989) 239-247
    • (1989) Mol Biochem Parasitol , vol.35 , pp. 239-247
    • Reduker, D.W.1    Jasmer, D.P.2    Goff, W.L.3    Perryman, L.E.4    Davis, W.C.5    McGuire, T.C.6
  • 13
    • 0035919578 scopus 로고    scopus 로고
    • Recombinant BCG vaccines
    • Ohara N., and Yamada T. Recombinant BCG vaccines. Vaccine 19 (2001) 4089-4098
    • (2001) Vaccine , vol.19 , pp. 4089-4098
    • Ohara, N.1    Yamada, T.2
  • 14
    • 0028920662 scopus 로고
    • Recombinant BCG strains expressing the SIVmac251 nef gene induce proliferative and CTL responses against nef synthetic peptides in mice
    • Winter N., Lagranderie M., Gangloff S., Leclerc C., Gheorghiu M., and Gicquel B. Recombinant BCG strains expressing the SIVmac251 nef gene induce proliferative and CTL responses against nef synthetic peptides in mice. Vaccine 13 (1995) 471-478
    • (1995) Vaccine , vol.13 , pp. 471-478
    • Winter, N.1    Lagranderie, M.2    Gangloff, S.3    Leclerc, C.4    Gheorghiu, M.5    Gicquel, B.6
  • 15
    • 0029098551 scopus 로고
    • Recombinant BCG expressing the Leishmania surface antigen Gp63 induces protective immunity against Leishmania major infection in BALB/c mice
    • Abdelhak S., Louzir H., Timm J., Blel L., Benlasfar Z., Lagranderie M., et al. Recombinant BCG expressing the Leishmania surface antigen Gp63 induces protective immunity against Leishmania major infection in BALB/c mice. Microbiology 141 (1995) 1585-1592
    • (1995) Microbiology , vol.141 , pp. 1585-1592
    • Abdelhak, S.1    Louzir, H.2    Timm, J.3    Blel, L.4    Benlasfar, Z.5    Lagranderie, M.6
  • 16
    • 0027141144 scopus 로고
    • Effective immunization against cutaneous leishmaniasis with recombinant Bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63
    • Connell N.D., Medina-Acosta E., McMaster W.R., Bloom B.R., and Russell D.G. Effective immunization against cutaneous leishmaniasis with recombinant Bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63. Proc Natl Acad Sci USA 90 (1993) 11473-11477
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11473-11477
    • Connell, N.D.1    Medina-Acosta, E.2    McMaster, W.R.3    Bloom, B.R.4    Russell, D.G.5
  • 17
    • 0032494134 scopus 로고    scopus 로고
    • Recombinant Mycobacterium bovis Bacillus Calmette-Guérin secreting merozoite surface protein 1 (MSP1) induces protection against rodent malaria parasite infection depending on MSP1-stimulated interferon gamma and parasite-specific antibodies
    • Matsumoto S., Yukitake H., Kanbara H., and Yamada T. Recombinant Mycobacterium bovis Bacillus Calmette-Guérin secreting merozoite surface protein 1 (MSP1) induces protection against rodent malaria parasite infection depending on MSP1-stimulated interferon gamma and parasite-specific antibodies. J Exp Med 188 (1998) 845-854
    • (1998) J Exp Med , vol.188 , pp. 845-854
    • Matsumoto, S.1    Yukitake, H.2    Kanbara, H.3    Yamada, T.4
  • 18
    • 0033855833 scopus 로고    scopus 로고
    • Recombinant Mycobacterium bovis BCG expressing pertussis toxin subunit S1 induces protection against an intracerebral challenge with live Bordetella pertussis in mice
    • Nascimento I.P., Dias W.O., Mazzantini R.P., Miyaji E.N., Gamberini M., Quintilio W., et al. Recombinant Mycobacterium bovis BCG expressing pertussis toxin subunit S1 induces protection against an intracerebral challenge with live Bordetella pertussis in mice. Infect Immun 68 (2000) 4877-4883
    • (2000) Infect Immun , vol.68 , pp. 4877-4883
    • Nascimento, I.P.1    Dias, W.O.2    Mazzantini, R.P.3    Miyaji, E.N.4    Gamberini, M.5    Quintilio, W.6
  • 20
    • 2542550555 scopus 로고    scopus 로고
    • Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni protects mice from cercarial challenge
    • Varaldo P.B., Leite L.C., Dias W.O., Miyaji E.N., Torres F.I., Gebara V.C., et al. Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni protects mice from cercarial challenge. Infect Immun 72 (2004) 3336-3343
    • (2004) Infect Immun , vol.72 , pp. 3336-3343
    • Varaldo, P.B.1    Leite, L.C.2    Dias, W.O.3    Miyaji, E.N.4    Torres, F.I.5    Gebara, V.C.6
  • 21
    • 18244423060 scopus 로고    scopus 로고
    • The kinetics of specific immune responses in rhesus monkeys inoculated with live recombinant BCG expressing SIV Gag, Pol, Env and Nef proteins
    • Leung N.J., Aldovini A., Young R., Jarvis M.A., Smith J.M., Meyer D., et al. The kinetics of specific immune responses in rhesus monkeys inoculated with live recombinant BCG expressing SIV Gag, Pol, Env and Nef proteins. Virology 268 (2000) 94-103
    • (2000) Virology , vol.268 , pp. 94-103
    • Leung, N.J.1    Aldovini, A.2    Young, R.3    Jarvis, M.A.4    Smith, J.M.5    Meyer, D.6
  • 22
    • 0027207231 scopus 로고
    • Immunization with recombinant BCG-SIV elicits SIV-specific cytotoxic T lymphocytes in rhesus monkeys
    • Yasutomi Y., Koenig S., Haun S.S., Stover C.K., Jackson R.K., Conard P., et al. Immunization with recombinant BCG-SIV elicits SIV-specific cytotoxic T lymphocytes in rhesus monkeys. J Immunol 150 (1993) 3101-3107
    • (1993) J Immunol , vol.150 , pp. 3101-3107
    • Yasutomi, Y.1    Koenig, S.2    Haun, S.S.3    Stover, C.K.4    Jackson, R.K.5    Conard, P.6
  • 25
    • 0018831575 scopus 로고
    • Babesia bovis: continuous cultivation in a microaerophilous stationary phase culture
    • Levi M.G., and Ristic M. Babesia bovis: continuous cultivation in a microaerophilous stationary phase culture. Science 207 (1980) 1218-1220
    • (1980) Science , vol.207 , pp. 1218-1220
    • Levi, M.G.1    Ristic, M.2
  • 26
    • 0035079440 scopus 로고    scopus 로고
    • Genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: evidence for horizontal transfer and identification of plasmid maintenance systems
    • Le Dantec C., Winter N., Gicquel B., Vincent V., and Picardeau M. Genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: evidence for horizontal transfer and identification of plasmid maintenance systems. J Bacteriol 183 (2001) 2157-2164
    • (2001) J Bacteriol , vol.183 , pp. 2157-2164
    • Le Dantec, C.1    Winter, N.2    Gicquel, B.3    Vincent, V.4    Picardeau, M.5
  • 27
    • 0034214309 scopus 로고    scopus 로고
    • Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: MalE
    • Himmelrich H., Lo-Man R., Winter N., Guermonprez P., Sedlik C., Rojas M., et al. Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: MalE. Vaccine 18 (2000) 2636-2647
    • (2000) Vaccine , vol.18 , pp. 2636-2647
    • Himmelrich, H.1    Lo-Man, R.2    Winter, N.3    Guermonprez, P.4    Sedlik, C.5    Rojas, M.6
  • 29
    • 0025781256 scopus 로고
    • Cell-mediated immune responses to Babesia bovis merozoite antigens in cattle following infection with tick-derived or cultured parasites
    • Brown W.C., Logan K.S., Wagner G.G., and Tetzlaff C.L. Cell-mediated immune responses to Babesia bovis merozoite antigens in cattle following infection with tick-derived or cultured parasites. Infect Immun 59 (1991) 2418-2426
    • (1991) Infect Immun , vol.59 , pp. 2418-2426
    • Brown, W.C.1    Logan, K.S.2    Wagner, G.G.3    Tetzlaff, C.L.4
  • 30
    • 0026642657 scopus 로고
    • Characterization of the major membrane protein of virulent Mycobacterium tuberculosis
    • Lee B.Y., Hefta S.A., and Brennan P.J. Characterization of the major membrane protein of virulent Mycobacterium tuberculosis. Infect Immun 60 (1992) 2066-2074
    • (1992) Infect Immun , vol.60 , pp. 2066-2074
    • Lee, B.Y.1    Hefta, S.A.2    Brennan, P.J.3
  • 31
    • 0027254484 scopus 로고
    • Protective immunity elicited by recombinant Bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine
    • Stover C.K., Bansal G.P., Hanson M.S., Burlein J.E., Palaszynski S.R., Young J.F., et al. Protective immunity elicited by recombinant Bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine. J Exp Med 178 (1993) 197-209
    • (1993) J Exp Med , vol.178 , pp. 197-209
    • Stover, C.K.1    Bansal, G.P.2    Hanson, M.S.3    Burlein, J.E.4    Palaszynski, S.R.5    Young, J.F.6
  • 32
    • 0037083489 scopus 로고    scopus 로고
    • Cell-mediated immunity induced by recombinant Mycobacterium bovis Bacille Calmette-Guérin strains against an intracellular bacterial pathogen: importance of antigen secretion or membrane-targeted antigen display as lipoprotein for vaccine efficacy
    • Grode L., Kursar M., Fensterle J., Kaufmann S.H., and Hess J. Cell-mediated immunity induced by recombinant Mycobacterium bovis Bacille Calmette-Guérin strains against an intracellular bacterial pathogen: importance of antigen secretion or membrane-targeted antigen display as lipoprotein for vaccine efficacy. J Immunol 168 (2002) 1869-1876
    • (2002) J Immunol , vol.168 , pp. 1869-1876
    • Grode, L.1    Kursar, M.2    Fensterle, J.3    Kaufmann, S.H.4    Hess, J.5
  • 33
    • 33644848136 scopus 로고    scopus 로고
    • Induction of humoral immunity in response to immunization with recombinant Mycobacterium bovis BCG expressing the S1 subunit of Bordetella pertussis toxin
    • Medeiros M., Armôa G.R., Dellagostin O.A., and McIntosh D. Induction of humoral immunity in response to immunization with recombinant Mycobacterium bovis BCG expressing the S1 subunit of Bordetella pertussis toxin. Can J Microbiol 51 (2005) 1015-1020
    • (2005) Can J Microbiol , vol.51 , pp. 1015-1020
    • Medeiros, M.1    Armôa, G.R.2    Dellagostin, O.A.3    McIntosh, D.4
  • 34
    • 0027987466 scopus 로고
    • Structural instability of recombinant plasmids in mycobacteria
    • Haeseleer F. Structural instability of recombinant plasmids in mycobacteria. Res Microbiol 145 (1994) 683-687
    • (1994) Res Microbiol , vol.145 , pp. 683-687
    • Haeseleer, F.1
  • 35
    • 0036958443 scopus 로고    scopus 로고
    • Expression of foreign genes in Mycobacterium bovis BCG strains using different promoters reveals instability of the hsp60 promoter for expression of foreign genes in Mycobacterium bovis BCG strains
    • Al-Zarouni M., and Dale J.W. Expression of foreign genes in Mycobacterium bovis BCG strains using different promoters reveals instability of the hsp60 promoter for expression of foreign genes in Mycobacterium bovis BCG strains. Tuberculosis 82 (2002) 283-291
    • (2002) Tuberculosis , vol.82 , pp. 283-291
    • Al-Zarouni, M.1    Dale, J.W.2
  • 36
    • 0036139428 scopus 로고    scopus 로고
    • Plasmidic versus insertional cloning of heterologous genes in Mycobacterium bovis BCG: impact on in vivo antigen persistence and immune responses
    • Méderlé I., Bourguin I., Ensergueix D., Badell E., Moniz-Peireira J., Gicquel B., et al. Plasmidic versus insertional cloning of heterologous genes in Mycobacterium bovis BCG: impact on in vivo antigen persistence and immune responses. Infect Immun 70 (2002) 303-314
    • (2002) Infect Immun , vol.70 , pp. 303-314
    • Méderlé, I.1    Bourguin, I.2    Ensergueix, D.3    Badell, E.4    Moniz-Peireira, J.5    Gicquel, B.6
  • 37
    • 0037686337 scopus 로고    scopus 로고
    • Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens
    • Buddle B.M., Pollock J.M., Skinner M.A., and Wedlock D.N. Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens. Int J Parasitol 33 (2003) 555-566
    • (2003) Int J Parasitol , vol.33 , pp. 555-566
    • Buddle, B.M.1    Pollock, J.M.2    Skinner, M.A.3    Wedlock, D.N.4
  • 38
    • 0036266656 scopus 로고    scopus 로고
    • Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis
    • Vordermeier H.M., Chambers M.A., Cockle P.J., Whelan A.O., Simmons J., and Hewinson R.G. Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis. Infect Immun 70 (2002) 3026-3032
    • (2002) Infect Immun , vol.70 , pp. 3026-3032
    • Vordermeier, H.M.1    Chambers, M.A.2    Cockle, P.J.3    Whelan, A.O.4    Simmons, J.5    Hewinson, R.G.6
  • 39
    • 0035008142 scopus 로고    scopus 로고
    • Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle
    • Vordermeier H.M., Whelan A., Cockle P.J., Farrant L., Palmer N., and Hewinson R.G. Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle. Clin Diagn Lab Immunol 8 (2001) 571-578
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 571-578
    • Vordermeier, H.M.1    Whelan, A.2    Cockle, P.J.3    Farrant, L.4    Palmer, N.5    Hewinson, R.G.6
  • 40
    • 0008774173 scopus 로고    scopus 로고
    • An ESAT-6 knockout mutant of Mycobacterium bovis produced by homologous recombination will be useful for development of a live tuberculosis vaccine
    • Wards B.J., de Lisle G.W., and Collins D.M. An ESAT-6 knockout mutant of Mycobacterium bovis produced by homologous recombination will be useful for development of a live tuberculosis vaccine. Tubercle Lung Dis 80 (2000) 1985-1989
    • (2000) Tubercle Lung Dis , vol.80 , pp. 1985-1989
    • Wards, B.J.1    de Lisle, G.W.2    Collins, D.M.3
  • 42
    • 0344631617 scopus 로고    scopus 로고
    • Humoral and cellular immune responses in mice immunized with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein
    • Abomoelak B., Huygen K., Kremer L., Turnee M., and Locht C. Humoral and cellular immune responses in mice immunized with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein. Infect Immun 67 (1999) 5100-5105
    • (1999) Infect Immun , vol.67 , pp. 5100-5105
    • Abomoelak, B.1    Huygen, K.2    Kremer, L.3    Turnee, M.4    Locht, C.5
  • 43
    • 0029159816 scopus 로고
    • Activity of mycobacterial promoters during intracellular and extracellular growth
    • Dellagostin O.A., Esposito G., Earles L.J., Dale J.W., and McFadden J.J. Activity of mycobacterial promoters during intracellular and extracellular growth. Microbiology 141 (1995) 1785-1792
    • (1995) Microbiology , vol.141 , pp. 1785-1792
    • Dellagostin, O.A.1    Esposito, G.2    Earles, L.J.3    Dale, J.W.4    McFadden, J.J.5
  • 44
    • 0028079877 scopus 로고
    • Escherichia coli-mycobacteria shuttle vectors for operon and gene fusions to lacZ: the pJEM
    • Timm J., Lim E.M., and Gicquel B. Escherichia coli-mycobacteria shuttle vectors for operon and gene fusions to lacZ: the pJEM. J Bacteriol 176 (1994) 6749-6753
    • (1994) J Bacteriol , vol.176 , pp. 6749-6753
    • Timm, J.1    Lim, E.M.2    Gicquel, B.3
  • 45
    • 0024988991 scopus 로고
    • Translation initiation in Escherichia coli: old and new questions
    • Jacques N., and Dreyfus M. Translation initiation in Escherichia coli: old and new questions. Mol Microbiol 4 7 (1990) 1063-1067
    • (1990) Mol Microbiol , vol.4 , Issue.7 , pp. 1063-1067
    • Jacques, N.1    Dreyfus, M.2
  • 46
    • 0036784666 scopus 로고    scopus 로고
    • Cellular localization of Babesia bovis merozoite rhoptry-associated protein 1 and its erythrocyte-binding activity
    • Yokoyama N., Suthisak B., Hirata H., Matsuo T., Inoue N., Sugimoto C., et al. Cellular localization of Babesia bovis merozoite rhoptry-associated protein 1 and its erythrocyte-binding activity. Infect Immun 70 (2002) 5822-5826
    • (2002) Infect Immun , vol.70 , pp. 5822-5826
    • Yokoyama, N.1    Suthisak, B.2    Hirata, H.3    Matsuo, T.4    Inoue, N.5    Sugimoto, C.6
  • 47
    • 0036130659 scopus 로고    scopus 로고
    • Immunodominant epitopes in Babesia bovis rhoptry-associated protein 1 that elicit memory CD4(+)-T-lymphocyte responses in B. bovis-immune individuals are located in the amino-terminal domain
    • Norimine J., Suarez C.E., McElwain T.F., Florin-Christensen M., and Brown W.C. Immunodominant epitopes in Babesia bovis rhoptry-associated protein 1 that elicit memory CD4(+)-T-lymphocyte responses in B. bovis-immune individuals are located in the amino-terminal domain. Infect Immun 70 (2002) 2039-2048
    • (2002) Infect Immun , vol.70 , pp. 2039-2048
    • Norimine, J.1    Suarez, C.E.2    McElwain, T.F.3    Florin-Christensen, M.4    Brown, W.C.5
  • 49
    • 0031733781 scopus 로고    scopus 로고
    • Analysis of the Mycobacterium bovis hsp60 promoter activity in recombinant Mycobacterium avium
    • Batoni G., Maisetta G., et al. Analysis of the Mycobacterium bovis hsp60 promoter activity in recombinant Mycobacterium avium. FEMS Microb Lett 169 (1998) 117-124
    • (1998) FEMS Microb Lett , vol.169 , pp. 117-124
    • Batoni, G.1    Maisetta, G.2
  • 50
    • 29244457803 scopus 로고    scopus 로고
    • Extraordinarily few organisms of a live recombinant BCG vaccine against tuberculosis induce maximal cell-mediated and protective immunity
    • Horwitz M.A., Harth G., Dillon B.J., and Maslesa-Galic S. Extraordinarily few organisms of a live recombinant BCG vaccine against tuberculosis induce maximal cell-mediated and protective immunity. Vaccine 24 (2006) 443-451
    • (2006) Vaccine , vol.24 , pp. 443-451
    • Horwitz, M.A.1    Harth, G.2    Dillon, B.J.3    Maslesa-Galic, S.4
  • 51
    • 12344281084 scopus 로고    scopus 로고
    • Factors influencing the immune response to foreign antigen expressed in recombinant BCG vaccines
    • Dennehy M., and Williamson A.L. Factors influencing the immune response to foreign antigen expressed in recombinant BCG vaccines. Vaccine 23 (2005) 1209-1224
    • (2005) Vaccine , vol.23 , pp. 1209-1224
    • Dennehy, M.1    Williamson, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.