Effects of arsenic trioxide on the cellular proliferation, apoptosis and differentiation of human neuroblastoma cells

Cancer Letters

Volumn 246, Issue 1-2, 2007, Pages 122-128

  Cheung, William M W ^a   Chu, Patrick W K ^a   Kwong, Yok L ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Arsenic trioxide; PKC; Retinoic acid; Trk

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ARSENIC TRIOXIDE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE 3; NEUROFILAMENT PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE A; TYROSINE 3 MONOOXYGENASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; ARSENICALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; GROWTH INHIBITORS; HUMANS; INDOLES; NEUROBLASTOMA; NEUROFILAMENT PROTEINS; NEURONS; OXIDES; PROTEIN KINASE C; RECEPTOR, TRKA; RECEPTOR, TRKB; TYROSINE 3-MONOOXYGENASE; UP-REGULATION;

EID: 33845634372     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2006.02.009     Document Type: Article

References (25)

1. 3 exerts dose-dependent dual effects on APL cells. Blood 89 (1997) 3345-3353
2. Kwong Y.L., and Todd D. Delicious poison: arsenic trioxide for the treatment of leukemia. Blood 89 (1997) 3487-3488
3. Cai X., Shen Y.L., Zhu Q., Jia P.M., Yu Y., Zhou L., et al. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia 14 (2000) 262-270
4. Verma A., Mohindru M., Deb D.K., Sassano A., Kambhampati S., Ravandi F., et al. Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide. J. Biol. Chem. 277 (2002) 44988-44995
5. Murgo A.J. Clinical trials of arsenic trioxide in hematologic and solid tumors: overview of the national cancer institute cooperative research and development studies. Oncologist 6 (2001) 22-28
6. Cheung W.M.W., Chu A.H., Chu P.W.K., and Ip N.Y. Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation. J. Biol. Chem. 276 (2001) 17083-17091
7. Cheung W.M.W., Hui W.S., Chu P.W.K., Chiu S.W., and Ip N.Y. Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat PC12 cells. Fed. Eur. Biochem. Soc. Lett. 486 (2000) 291-296
8. Zhuang S., Ouedraogo G.D., and Kochevar I.E. Downregulation of epidermal growth factor receptor signaling by singlet oxygen through activation of caspase-3 and protein phosphatases. Oncogene 22 (2003) 4413-4424
9. Elder G.A., Friedrich Jr. V.L., Kang C., Bosco P., Gourov A., Tu P.H., et al. Requirement of heavy neurofilament subunit in the development of axons with large calibers. J. Cell Biol. 143 (1998) 195-205
10. Nakagawara A., Arima-Nakagawara M., Scavarda N.J., Azar C.G., Cantor A.B., and Brodeur G.M. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N. Engl. J. Med. 328 (1993) 847-854
11. Kogner P., Barbany G., Dominici C., Castello M.A., Raschella G., and Persson H. Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis. Cancer Res. 53 (1993) 2044-2050
12. Nakagawara A., Azar C.G., Scavarda N.J., and Brodeur G.M. Expression and function of TRK-B and BDNF in human neuroblastomas. Mol. Cell. Biol. 14 (1994) 759-767 14
13. Ghayur T., Hugunin M., Talanian R.V., Ratnofsky S., Quinlan C., Emoto Y., et al. Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis. J. Exp. Med. 184 (1996) 2399-2404
14. Hogarty M.D. The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification. Cancer Lett. 197 (2003) 173-179
15. Wang Z.H., Yu D., Li H.K., Chow V.W., Ng C.C., Chan H.B., et al. Alteration of nuclear matrix protein composition of neuroblastoma cells after arsenic trioxide treatment. Anticancer Res. 21 (2001) 493-498
16. Akao Y., Nakagawa Y., and Akiyama K. Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro. Fed. Eur. Biochem. Soc. Lett. 455 (1999) 59-62
17. Sivak L.E., Pont-Kingdon G., Le K., Mayr G., Tai K.-F., Stevens B.T., and Carroll W.L. A novel intron element operates posttranscriptionally to regulate human N-myc expression. Mol. Cell. Biol. 19 (1999) 155-163
18. Aoyama M., Asai K., Shishikura T., Kawamoto T., Miyachi T., Yokoi T., et al. Human neuroblastomas with unfavorable biologies express high levels of brain-derived neurotrophic factor mRNA and a variety of its variants. Cancer Lett. 164 (2001) 51-60
19. Kothakota S., Azuma T., Reinhard C., Klippel A., Tang J., Chu K., et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278 (1997) 294-298
20. Degterev A., Boyce M., and Yuan J. A decade of caspases. Oncogene 22 (2003) 8543-8567
21. Boix J., Llecha N.Y., Yuste V.J., and Comella J.X. Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines. Neuropharmacology 36 (1997) 811-821
22. Leverrier S., Vallentin A., and Jouber D. Positive feedback of protein kinase C proteolytic activation during apoptosis. Biochem. J. 368 (2002) 905-913
23. Kambhampati S., Li Y., Verma A., Sassano A., Majchrzak B., Deb D.K., et al. Activation of protein kinase C delta by all-trans-retinoic acid. J. Biol. Chem. 278 (2003) 32544-32551
24. Schramm A., Schulte J.H., Astrahantseff K., Apostolov O., Limpt V., Sieverts H., et al. Biological effects of TrkA and TrkB receptor signaling in neuroblastoma. Cancer Lett. 228 (2005) 143-153
25. Hecht M., Schulte J.H., Eggert A., Wilting J., and Schweigerer L. The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. Carcinogenesis (2005) July 28 (Epub ahead of print)