Neprilysin-2

Handbook of Proteolytic Enzymes, Second Edition: Volume 1: Aspartic and Metallo Peptidases

Volumn 1, Issue , 2004, Pages 426-429

  Carpentier, Mélanie ^a   DesGroseillers, Luc ^a   Boileau, Guy ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33845611820     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-079611-3.50117-8     Document Type: Chapter

References (14)

1. N. Bonvouloir, N. Lemieux, P. Crine, G. Boileau and L. DesGroseillers (2001) Molecular cloning, tissue distribution, and chromosomal localization of MMEL2, a gene coding for a novel human member of the neutral endopeptidase-24.11 family. DNA Cell. Biol. 20 493-498.
2. M. Carpentier, M. Marcinkiewicz, G. Boileau and L. DesGroseillers (2003) The neuropeptide-degrading enzyme NL1 is expressed in specific neurons of mouse brain. Peptides 24 1083-1091.
3. N. Emoto and M. Yanagisawa (1995) Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. J. Biol. Chem. 270 15262-15268.
4. P. Fachinetti, C. Rose, J.C. Schwartz and T. Ouimet (2003) Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: a comparison with neprilysin and endothelin-converting enzyme. Neuroscience 118 627-639.
5. G. Ghaddar, A. Frota-Rochon, M. Carpentier, M. Marcinkiewicz, N. Seidah, P. Crine, L. DesGroseillers and G. Boileau (2000) Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family. Biochem. J. 347 419-429.
6. K. Ikeda, N. Emoto, S.B. Raharjo, Y. Nurhantari, K. Saiki, M. Yokoyama and M. Matsuo (1999) Molecular identification and characterization of a novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides. J. Biol. Chem. 274 32469-32477.
7. M.H. Lafrance, C. Vézina, Q. Wang, G. Boileau, P. Crine and G. Lemay (1994) Role of glycosylation in transport and enzymatic activity of neutral endopeptidase-24.11. Biochem. J. 302 683-688.
8. C. Oefner, A. D'Arcy, M. Hennig, F.K. Winkler and G.E. Dale (2000) Structure of human neutral endopeptidase (neprilysin) complexed with phosphoramidon. J. Mol. Biol. 296 341-349.
9. T. Ouimet, P. Facchinetti, C. Rose, M.-C. Bonhomme, C. Gros and J.-C. Schwartz (2000) Neprilysin II: a putative novel metalloprotease and its isoforms in CNS and testis. Biochem. Biophys. Res. Commun. 271 565-570.
10. S.B. Raharjo, N. Emoto, K. Ikeda, R. Sato, M. Yokoyama and M. Matsuo (2001) Alternative splicing regulates the endoplasmic reticulum localization or secretion of soluble secreted endopeptidase. J. Biol. Chem. 276 25612-25620.
11. C. Rose, S. Voisin, C. Gros, J.C. Shwartz and T. Ouimet (2002) Cell-specific activity of neprilysin 2 isoforms and enzymatic specificity compared with neprilysin. Biochem. J. 363 697-705.
12. K. Shirotani, S. Tsubuki, N. Iwata, Y. Takaki, W. Harigaya, K. Maruyama, S. Kiryu-Seo, H. Kiyama, H. Iwata, T. Tomita, T. Iwatsubo and T.C. Saido (2001) Neprilysin degrades both amyloid β peptide 1–40 and 1–42 most rapidly and efficiently among thiorphan and phosphoramidon-sensitive endopeptidases. J. Biol. Chem. 276 21895-21901.
13. A. Schweizer, O. Valdenaire, P. Nelböck, U. Deuschle, M.E. Dumas, J.G. Stumpf and B.M. Löffler (1997) Human endothelin converting enzyme (ECE-1): Three isoforms with distinct subcellular localization. Biochem. J. 328 871-877.
14. O. Valdenaire and A. Schweizer (2000) Endothelin-converting enzyme-like 1 (ECEL1; XCE): a putative metallopeptidase crucially involved in the nervous control of respiration. Biochem. Soc. Trans. 28 426-430.