Effect of drug loading on the transformation of vesicular into cubic nanoparticles during heat treatment of aqueous monoolein/poloxamer dispersions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 63, Issue 2, 2006, Pages 128-133

  Wörle, Gert ^a   Siekmann, Britta ^b   Bunjes, Heike ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Camurus AB   (Sweden)

Author keywords

Autoclaving; Colloidal drug carriers; Dispersions of cubic phase; Drug loading; Monoolein; Ultrastructural transformation

Indexed keywords

ALPHA TOCOPHEROL; BETAMETHASONE VALERATE; CHLORAMPHENICOL; DRUG CARRIER; GLYCEROL OLEATE; MICONAZOLE; NANOPARTICLE; POLOXAMER; UBIDECARENONE;

AQUEOUS SOLUTION; ARTICLE; AUTOCLAVE; DISPERSION; DRUG CONCENTRATION; DRUG DISTRIBUTION; DRUG TRANSFORMATION; HEAT TREATMENT; PARTICLE SIZE;

GLYCERIDES; HEAT; NANOTECHNOLOGY; PARTICLE SIZE; POLOXAMER; X-RAY DIFFRACTION;

EID: 33646845478     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.11.004     Document Type: Article

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