Enhancement of BCG-induced Th1 immune response through Vγ9Vδ2 T cell activation with non-peptidic drugs

Vaccine

Volumn 25, Issue 6, 2007, Pages 1023-1029

  Martino, Angelo ^a   Casetti, Rita ^a   Poccia, Fabrizio ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

; BCG; Dendritic cells

Indexed keywords

B7 ANTIGEN; BACILLUS CALMETTE GUERIN PLUS BROMOHYDRIN PIROPHOSPHATE; BACILLUS CALMETTE GUERIN PLUS ZOLEDRONIC ACID; BACTERIAL VACCINE; CD4 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CHEMOPROPHYLAXIS; COCULTURE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; IMMUNOPOTENTIATION; IMMUNOREGULATION; IMMUNOSTIMULATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; T LYMPHOCYTE ACTIVATION; TH1 CELL; TUBERCULOSIS;

ALCOHOLS; CD4-POSITIVE T-LYMPHOCYTES; COCULTURE TECHNIQUES; DENDRITIC CELLS; DIPHOSPHONATES; HUMANS; IMIDAZOLES; INTERLEUKIN-10; INTERLEUKIN-15; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; TH1 CELLS; TUBERCULOSIS VACCINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33845568804     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.09.070     Document Type: Article

References (35)

1. Rodriguez L.C., Diwan V.K., and Wheeler J.G. Protective effect of BCG against tuberculosis meningitis and miliary tuberculosis: a meta analisys. Int J Epidemiol 22 (1993) 1154-1158
2. Chihota V.N., Nyazema N.Z., Mashingaidze S., and Mutandiro B. TB infection: an exploratory study of BCG protective properties and the possible role of environmental mycobacteria. Cent Afr J Med 44 6 (1998) 145-148
3. Fine P.E. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 346 (1995) 1339-1345
4. Agger E.M., and Andersen P. A novel TB vaccine towards a strategy based on our understanding of BCG failure. Vaccine 21 1-2 (2002) 7-14
5. Kaufmann S.H. Immune response to tuberculosis: experimental animal models. Tuberculosis 83 (2003) 107-111
6. Boom W.H., Canaday D., Fulton S.A., Gehring A.J., Rojas R.E., and Torres M. Human immunity to M. tuberculosis: T cell subsets and antigen processing. Tuberculosis 83 1-3 (2003) 98-106
7. Banchereau J., and Steinman R. Dendritic cells and the control of the immunity. Nature 392 (1998) 245-252
8. Banchereau J., Briere F., and Caux C. Immunobiology of dendritic cells. Annu Rev Immunol 18 (2000) 767-811
9. Banchereau J., Schuler-Thurner B., Palucka A.K., and Schuler G. Dendritic cells as vectors for therapy. Cell 392 (2001) 271-274
10. Kim D.K., Lee H.G., Kim J.K., Park S.N., Choe I.S., Choe I.K., et al. Enhanced antigen-presenting activity and tumor necrosis factor-α-independent activation of dendritic cells following treatment with Mycobacterium bovis bacillus Calmette-Guerin. Immunology 97 (1999) 626-633
11. Liu E., Law H.K., and Lau Y.L. BCG promotes cord blood monocyte-derived dendritic cell maturation with nuclear Rel-B up-regulation and cytosolic I kappa B alpha and beta degradation. Pediatr Res 54 1 (2003) 105-112
12. Sander B., Skannsen-Saphir U., Damm O., Hakansson L., Anderson J., and Andersson U. Sequential production of Th1 and Th2 cytokines in response to live bacillus Calmette-Guerin. Immunology 86 (1995) 512-518
13. Martino A., Sacchi A., Sanarico N., Spadaro F., Ramoni C., Ciaramella A., et al. Dendritic cells derived from BCG-infected precursors induce Th2-like immune response. J Leukoc Biol 76 (2004) 827-834
14. Shankar G., Pestano L.A., and Bosch M.L. Interferon gamma added during Bacillus Calmette-Guerin induced dendritic cell maturation stimulates potent Th1 immune responseas. J Transl Med 1 (2003) 7-19
15. Munz C., Steinman R.M., and Fujii S. Dendritic cell maturation by innate lymphocytes: coordinate stimulation of innate and adaptive immunity. J Exp Med 202 (2005) 203-207
16. Ismaili J., Olislagers V., Poupot R., Fournie J.J., and Goldman M. Human gamma delta T-cells induce dendritic cell maturation. Clin Immunol 103 (2002) 296-302
17. Bonneville M., and Fournie J.J. Sensing cell stress and transformation through Vgamma9Vdelta2 T cell-mediated recognition of the isoprenoid pathway metabolites. Microbes Infect 7 (2005) 503-509
18. Constant P., Davodeau F., Peyrat M.A., Poquet Y., Puzo G., Bonneville M., et al. Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands. Science 264 (1994) 267-270
19. Chen Z.W., and Letvin N.L. Vgamma9 Vdelta2 + T cells and antimicrobial immune responses. Microbes Infect 5 (2003) 491-498
20. Gober H.J., Kistowska M., Angman L., Jeno P., Mori L., and De Libero G. Human T cell receptor gamma delta cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med 197 (2003) 163-168
21. Tanaka Y., Sano S., Nieves E., De Libero G., Rosa D., Modlin R.L., et al. Non-peptide ligands for human gamma delta T-cells. Proc Natl Acad Sci 91 17 (1994) 8175-8179
22. Thompson K., Rojas-Navea J., and Rogers M.J. Alkylamines cause V{gamma}9V{delta}2 T-cell activation and proliferation by inhibiting the mevalonate pathway. Blood 107 2 (2005) 651-654
23. Bennouna J., Medioni J., Rolland F., Misset J., Campone M., Sicard H., et al. Phase I clinical trial of Bromohydrin Pyrophosphate BrHPP (Phosphostim) a Vgamma9Vdelta2 T lymphocytes agonist in combination with low-dose interleukin-2 in patients with solid tumors. J Clin Oncol 23 (2005) 174s
24. Mariani S., Muraro M., Pantaleoni F., Fiore F., Nuschak B., Peola S., et al. Effector gamma delta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma. Leukemia 19 (2005) 664-670
25. Martino A., Casetti R., D'Alessandri A., Sacchi A., and Poccia F. Complementary function of gamma delta T-lymphocytes and dendritic cells in the response to isopentenyl-pyrophosphate and lipopolysaccharide antigens. J Clin Immunol 25 (2005) 230-237
26. Conti L., Casetti R., Cardone M., Varano B., Martino A., Belardelli F., et al. Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gamma delta T cells: role of CD86 and inflammatory cytokines. J Immunol 174 (2005) 252-260
27. Martino A., and Poccia F. Close encounters of different kinds: dendritic cells and gammadelta T cells heighten therapeutic applications. Immunol Lett 101 (2005) 115
28. Devilder M.C., Maillet S., Bouyge-Moreau I., Donnadieu E., Bonneville M., and Scotet E. Potentiation of antigen-stimulated Vgamma9Vdelta2 T cell cytokine production by immature dendritic cells (DC) and reciprocal effect on DC maturation. J Immunol 176 (2006) 1386-1393
29. Stenger S. Immunological control of tuberculosis: role of tumor necrosis factor and more. Annu Rheum Dis 64 (2005) 24-28
30. Tascon R.E., Soares C.S., Ragno E., Stavropoulos E.M., Hirst E.M., and Colston M.J. Mycobacterium tuberculosis-dendritic cells activated cells induce protective immunity in mice. Immunology 99 (2000) 473-480
31. Appelberg R. Protective role of interferon gamma, tumor necrosis factor alpha and interleukin-6 in Mycobacterium tuberculosis and M. avium infections. Immunobiology 191 (1994) 520-525
32. Kanegame H., and Tosato G. Activation of naïve and memory T cells by interleukin-15. Blood 88 (1996) 230-235
33. Forcina G., D'Ettore G., et al. Interleukin-15 modulates interferon-γ and β-chemockine production in patients with HIV infection: implications for immune based therapy. Cytokine 25 (2004) 283-290
34. Saito K., Yagjina T., Doi T., Yamada H., Sad S., Shen H., et al. Impaired protection against Mycoabcterium bovis bacillus Calmette-Guerin infection in IL-15 deficient mice. J Immunol 176 (2006) 1496-1504
35. Rook G.A., Dheda K., and Zumla A. Immune responses to tuberculosis in developing countries: implications for new vaccines. Nat Rev Immunol 5 (2005) 661-667