The effect of donor factors on human islet yield and their in vivo function

Progress in Transplantation

Volumn 16, Issue 4, 2006, Pages 350-354

  Sabek, Omaima M ^a   Cowan, Patricia ^a   Fraga, Daniel W ^b   Gaber, A Osama ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; COLLAGENASE 3; GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ARTICLE; CORRELATION ANALYSIS; DONOR; ENDOCRINE FUNCTION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PANCREAS FUNCTION; PANCREAS ISLET TRANSPLANTATION; SCID MOUSE; SURGICAL TECHNIQUE; TREATMENT OUTCOME;

EID: 33845427549     PISSN: 15269248     EISSN: None     Source Type: Journal    
DOI: 10.7182/prtr.16.4.26t7t536772343n2     Document Type: Article

References (28)

1. Federlin K, Pozza G. Indications for clinical islet transplantation today and in the forseeable future - the diabetologist's point of view. J Mol Med. January 1999:77:148-152.
2. Nanji SA, Shapiro AM. Advances in pancreatic islet transplantation in humans. Diabetes Obes Metab. January 2006; 8:15-25.
3. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230-238.
4. Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes. 2001;50:710-719.
5. Guignard AP, Oberholzer J, Benhamou PY, et al. Cost analysis of human islet transplantation for the treatment of type 1 diabetes in the Swiss-French Consortium GRAGIL. Diabetes Care. 2004;27:895-900.
6. Korsgren O, Nilsson B, Berne C, et al. Current status of clinical islet transplantation. Transplantation. 2005;79:1289-1293.
7. Matsumoto S, Zhang G, Qualley S, et al. Analysis of donor factors affecting human islet isolation with current isolation protocol. Transplant Proc. 2004;36:1034-1036.
8. Kim SC, Han DJ, Kang CH, et al. Analysis on donor and isolation-related factors of successful isolation of human islet of Langerhans from human cadaveric donors. Transplant Proc. 2005;37:3402-3403.
9. Brandhorst H, Brandhorst D, Hering BJ, et al. Body mass index of pancreatic donors: a decisive factor for human islet isolation. Exp Clin Endocrinol Diabetes. 1995;103(suppl 2):23-26.
10. Zeng Y, Torre MA, Karrison T, et al. The correlation between donor characteristics and the success of human islet isolation. Transplantation. 1994;57:954-958.
11. Sabek O, Hathaway D, Fraga D, et al. Influence of human donor factors on pancreatic collagenase digestion. Transplant Proc. 1998;30:353.
12. O'Gorman D, Kin T, Murdoch T, et al. The standardization of pancreatic donors for islet isolations. Transplantation. 2005;80:801-806.
13. Lakey JR, Warnock GL, Rajotte RV, et al. Variables in organ donors that affect the recovery of human islets of Langerhans. Transplantation. 1996;61:1047-1053.
14. Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes. 1988;37:413-420.
15. London NJM, James RFL, Bell PRF. Pancreatic Islet Transplantation, Islet Purification. Chapter 11. Austin, Tex: Landes; 1992.
16. Fraga DW, Sabek O, Hathaway DK, et al. A comparison of media supplement methods for the extended culture of human islet tissue. Transplantation. 1998;65:1060-1066.
17. Jansson L. The regulation of pancreatic islet blood flow. Diabetes Metab Rev. 1994;10:407-416.
18. Parr EL, Bowen KM, Lafferty KJ. Cellular changes in cultured mouse thyroid glands and islets of Langerhans. Transplantation. 1980;30:135-141.
19. Cattan P, Berney T, Schena S, et al. Early assessment of apoptosis in isolated islets of Langerhans. Transplantation. 2001;71:857-862.
20. Thomas FT, Contreras JL, Bilbao G, et al. Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation. Surgery. 1999;126:299-304.
21. Delaney CA, Pavlovic D, Hoorens A, et al. Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology. 1997;138:2610-2614.
22. Eckhoff DE, Smyth CA, Eckstein C, et al. Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction. Surgery. 2003;134:169-179.
23. Eizirik DL, Mandrup-Poulsen T. A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia. 2001;44:2115-2133.
24. Marshall D, Sabek O, Fraga D, et al. Examination of the molecular signature associated with islet dysfunction. Transplant Proc. 2005;37:1311-1312.
25. Sabek OM, Marshall DR, Minoru O, et al. OP-142 gene expression profile of nonfunctional human pancreatic islets: predictors of transplant failure? Transplant Proc. 2005;37:3441-3443.
26. Dionne KE, Colton CK, Yarmush ML. Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes. January 1993;42:12-21.
27. Rosenberg L, Wang R, Paraskevas S, et al. Structural and functional changes resulting from islet isolation lead to islet cell death. Surgery. 1999;126:393-398.
28. Lakey JR, Tsujimura T, Shapiro AM, et al. Preservation of the human pancreas before islet isolation using a two-layer (UW solution- perfluorochemical) cold storage method. Transplantation. 2002;74:1809-1811.